Basic Information
| Terpenoid ID | TKC079733 |
|
| Chirality | TKC010849 | |
| Cell line | 0 | |
| Protein target | 4 | |
| DiseaseNCIT | 0 | |
| ORDO | 0 | |
| ICD | 7 |
| Terpenoid ID | TKC079733 |
|
| Chirality | TKC010849 | |
| Cell line | 0 | |
| Protein target | 4 | |
| DiseaseNCIT | 0 | |
| ORDO | 0 | |
| ICD | 7 |
| ID | Cell Line | Synonyms | Value | Unit | Type | NCIt | ORDO |
|---|---|---|---|---|---|---|---|
| TKC079733 | MCF7 | 1.0 | ug ml-1 | ED50 | C4194 | ||
| TKC079733 | A498 | A498 | 48.0 | ug ml-1 | ED50 | C9385 | Orphanet_217071 |
| TKC079733 | A549 | 14.0 | ug ml-1 | ED50 | C3512 | ||
| TKC079733 | HT-29 | HT 29; HT29 | 31.0 | ug ml-1 | ED50 | C4349 | |
| TKC079733 | MIA PaCa-2 | MIA-PaCa-2; MIA-PACA-2; MIA-Pa-Ca-2; MIA Paca2; MIA PaCa2; MiaPaCa-2; MIAPACA-2; MiaPaca.2; MiaPaCa2; Miapaca2; MIAPaCa2; MIAPACA2; Mia PACA 2; MIAPaCa-2; PaCa2; MiaPaCa | 22.0 | ug ml-1 | ED50 | C9120 | |
| TKC079733 | PC-3 | PC3; PC.3 | 15.0 | ug ml-1 | ED50 | C4863 | |
| TKC079733 | LLC-MK2 | Llc-Mk2; LLC-MK-2; LLC-MK2 Original; LLCMK2; LLcMK2; Lilly Laboratories Culture-Monkey Kidney 2; MK2 | 76100.0 | nM | CC50 | ||
| TKC079733 | HepG2 | 50720.0 | nM | IC50 | C3728 | Orphanet_449 | |
| TKC079733 | PBMC | 2.0 | nM | IC50 |
| ID | Uniport | Pref_name | Gene name | value | unit | type |
|---|---|---|---|---|---|---|
| TKC079733 | P18031 | Tyrosine-protein phosphatase non-receptor type 1 | PTPN1 | 20200 | nM | IC50 |
| TKC079733 | Q4QEW7 | Dihydroorotate dehydrogenase | DHODH | 31500 | nM | IC50 |
| TKC079733 | P28845 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | HSD11B1 | 82 | % | Inhibition |
| TKC079733 | P50172 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | Hsd11b1 | 357 | nM | IC50 |
| TKC079733 | Q02127 | Dihydroorotate dehydrogenase | DHODH | 28 | % | Inhibition |
| TKC079733 | P51661 | Corticosteroid 11-beta-dehydrogenase isozyme 2 | Hsd11b2 | 500000 | nM | IC50 |
| Uniport ID | Uniport Name | ICD-11 |
|---|---|---|
| P18031 | PTN1_HUMAN | Type 2 diabetes mellitus [ICD-11: 5A11] |
| P18031 | PTN1_HUMAN | Acute diabete complication [ICD-11: 5A2Y] |
| P18031 | PTN1_HUMAN | Breast cancer [ICD-11: 2C60-2C6Y] |
| P18031 | PTN1_HUMAN | Obesity [ICD-11: 5B80-5B81] |
| P18031 | PTN1_HUMAN | Ophthalmic devices/implants/grafts injury [ICD-11: PK97] |
| P18031 | PTN1_HUMAN | Postoperative inflammation [ICD-11: 1A00-CA43] |
| P18031 | PTN1_HUMAN | Metabolic disorder [ICD-11: 5C50-5D2Z] |
| P18031 | PTN1_HUMAN | Type 2 diabetes mellitus [ICD-11: 5A11] |
| P28845 | DHI1_HUMAN | Influenza [ICD-11: 1E30-1E32] |
| P28845 | DHI1_HUMAN | Lupus erythematosus [ICD-11: 4A40] |
| P28845 | DHI1_HUMAN | Myasthenia gravis [ICD-11: 8C6Y] |
| P28845 | DHI1_HUMAN | Type 2 diabetes mellitus [ICD-11: 5A11] |
| P28845 | DHI1_HUMAN | Acute diabete complication [ICD-11: 5A2Y] |
| P28845 | DHI1_HUMAN | Alzheimer disease [ICD-11: 8A20] |
| P28845 | DHI1_HUMAN | Glaucoma [ICD-11: 9C61] |
| P28845 | DHI1_HUMAN | Hyper-lipoproteinaemia [ICD-11: 5C80] |
| P28845 | DHI1_HUMAN | Metabolic disorder [ICD-11: 5C50-5D2Z] |
| P28845 | DHI1_HUMAN | Inborn lipid metabolism error [ICD-11: 5C52] |
| P28845 | DHI1_HUMAN | Obesity [ICD-11: 5B80-5B81] |
| Q02127 | PYRD_HUMAN | Hepatitis virus infection [ICD-11: 1E50-1E51] |
| Q02127 | PYRD_HUMAN | Hyper-lipoproteinaemia [ICD-11: 5C80] |
| Q02127 | PYRD_HUMAN | Multiple sclerosis [ICD-11: 8A40] |
| Q02127 | PYRD_HUMAN | Rheumatoid arthritis [ICD-11: FA20] |
| Q02127 | PYRD_HUMAN | Acute myeloid leukaemia [ICD-11: 2A60] |
| Q02127 | PYRD_HUMAN | COVID-19 [ICD-11: 1D6Y] |
| Q02127 | PYRD_HUMAN | Indeterminate colitis [ICD-11: DD72] |
| Q02127 | PYRD_HUMAN | Malignant haematopoietic neoplasm [ICD-11: 2B33] |
| Q02127 | PYRD_HUMAN | Transplant rejection [ICD-11: NE84] |