TKC104905
|
O76083 |
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A |
None |
4830 |
nM |
IC50 |
TKC151523
|
P08908 |
5-hydroxytryptamine receptor 1A |
None |
>100000 |
nM |
Ki |
TKC205544
|
P08908 |
5-hydroxytryptamine receptor 1A |
None |
4500 |
nM |
Ki |
TKC205544
|
P08908 |
5-hydroxytryptamine receptor 1A |
None |
1500 |
nM |
Ki |
TKC205544
|
P08908 |
5-hydroxytryptamine receptor 1A |
None |
642 |
nM |
Ki |
TKC205544
|
P08908 |
5-hydroxytryptamine receptor 1A |
None |
1258.92 |
nM |
Ki |
TKC206544
|
P08908 |
5-hydroxytryptamine receptor 1A |
None |
>10000 |
nM |
Ki |
TKC206549
|
P08908 |
5-hydroxytryptamine receptor 1A |
None |
30 |
pM well-1 |
cAMP |
TKC100416
|
P08913 |
Alpha-2A adrenergic receptor |
None |
31623 |
nM |
Kd |
TKC205544
|
P08913 |
Alpha-2A adrenergic receptor |
None |
0 |
nM |
Ki |
TKC205544
|
P08913 |
Alpha-2A adrenergic receptor |
None |
0 |
nM |
Ki |
TKC205544
|
P08913 |
Alpha-2A adrenergic receptor |
None |
0.32 |
nM |
Ki |
TKC205544
|
P08913 |
Alpha-2A adrenergic receptor |
None |
132 |
nM |
Ki |
TKC205544
|
P08913 |
Alpha-2A adrenergic receptor |
None |
2.7 |
nM |
Ki |
TKC205544
|
P08913 |
Alpha-2A adrenergic receptor |
None |
3.6 |
nM |
Ki |
TKC205544
|
P08913 |
Alpha-2A adrenergic receptor |
None |
0.43 |
nM |
Ki |
TKC205544
|
P08913 |
Alpha-2A adrenergic receptor |
None |
3.76 |
nM |
Ki |
TKC205544
|
P08913 |
Alpha-2A adrenergic receptor |
None |
0.71 |
nM |
Ki |
TKC205544
|
P08913 |
Alpha-2A adrenergic receptor |
None |
1.2 |
nM |
Ki |
TKC205544
|
P08913 |
Alpha-2A adrenergic receptor |
None |
7.94 |
nM |
Ki |
TKC205544
|
P08913 |
Alpha-2A adrenergic receptor |
None |
2.5 |
nM |
Ki |
TKC205544
|
P08913 |
Alpha-2A adrenergic receptor |
None |
3.5 |
nM |
Ki |
TKC205544
|
P08913 |
Alpha-2A adrenergic receptor |
None |
170 |
nM |
IC50 |
TKC205544
|
P08913 |
Alpha-2A adrenergic receptor |
None |
8 |
nM |
IC50 |
TKC205544
|
P08913 |
Alpha-2A adrenergic receptor |
None |
7.5 |
nM |
Ki |
TKC205544
|
P08913 |
Alpha-2A adrenergic receptor |
None |
1.8 |
nM |
Ki |
TKC205544
|
P08913 |
Alpha-2A adrenergic receptor |
None |
8.5 |
nM |
EC50 |
TKC205544
|
P08913 |
Alpha-2A adrenergic receptor |
None |
3.67 |
nM |
IC50 |
TKC205806
|
P08913 |
Alpha-2A adrenergic receptor |
None |
8 |
nM |
Ki |
TKC206544
|
P11229 |
Muscarinic acetylcholine receptor M1 |
None |
>10000 |
nM |
Ki |
TKC205544
|
P18825 |
Alpha-2C adrenergic receptor |
None |
1 |
nM |
Ki |
TKC205544
|
P18825 |
Alpha-2C adrenergic receptor |
None |
0.13 |
nM |
Ki |
TKC205544
|
P18825 |
Alpha-2C adrenergic receptor |
None |
0.78 |
nM |
Ki |
TKC205544
|
P18825 |
Alpha-2C adrenergic receptor |
None |
0.55 |
nM |
Ki |
TKC205544
|
P18825 |
Alpha-2C adrenergic receptor |
None |
0.25 |
nM |
Ki |
TKC205544
|
P18825 |
Alpha-2C adrenergic receptor |
None |
0.5 |
nM |
Ki |
TKC205544
|
P18825 |
Alpha-2C adrenergic receptor |
None |
2.3 |
nM |
Ki |
TKC205544
|
P18825 |
Alpha-2C adrenergic receptor |
None |
1.9 |
nM |
Ki |
TKC205544
|
P18825 |
Alpha-2C adrenergic receptor |
None |
0.8 |
nM |
Ki |
TKC205544
|
P18825 |
Alpha-2C adrenergic receptor |
None |
27.1 |
nM |
IC50 |
TKC205806
|
P18825 |
Alpha-2C adrenergic receptor |
None |
5 |
nM |
Ki |
TKC005313
|
P21728 |
D(1A) dopamine receptor |
None |
517 |
nM |
Potency |
TKC035272
|
P21728 |
D(1A) dopamine receptor |
None |
12589 |
nM |
Potency |
TKC035984
|
P21728 |
D(1A) dopamine receptor |
None |
20 |
nM |
Potency |
TKC084630
|
P21728 |
D(1A) dopamine receptor |
None |
14125 |
nM |
Potency |
TKC092297
|
P21728 |
D(1A) dopamine receptor |
None |
2909 |
nM |
Potency |
TKC205544
|
P21728 |
D(1A) dopamine receptor |
None |
2909 |
nM |
Potency |
TKC205544
|
P21728 |
D(1A) dopamine receptor |
None |
>10000 |
nM |
Ki |
TKC206544
|
P21728 |
D(1A) dopamine receptor |
None |
>10000 |
nM |
Ki |
TKC206622
|
P21728 |
D(1A) dopamine receptor |
None |
231 |
nM |
Potency |
TKC206690
|
P21728 |
D(1A) dopamine receptor |
None |
26 |
nM |
Potency |
TKC206777
|
P21728 |
D(1A) dopamine receptor |
None |
23109 |
nM |
Potency |
TKC206816
|
P21728 |
D(1A) dopamine receptor |
None |
14125 |
nM |
Potency |
TKC005454
|
P22303 |
Acetylcholinesterase |
None |
>6410 |
nM |
Ki |
TKC008149
|
P22303 |
Acetylcholinesterase |
None |
0 |
ug |
Activity |
TKC010478
|
P22303 |
Acetylcholinesterase |
None |
14500 |
nM |
IC50 |
TKC010538
|
P22303 |
Acetylcholinesterase |
None |
22800 |
nM |
IC50 |
TKC011270
|
P22303 |
Acetylcholinesterase |
None |
>10 |
ug |
Activity |
TKC012269
|
P22303 |
Acetylcholinesterase |
None |
>22 |
% |
Inhibition |
TKC014568
|
P22303 |
Acetylcholinesterase |
None |
>50000 |
nM |
IC50 |
TKC014568
|
P22303 |
Acetylcholinesterase |
None |
>100000 |
nM |
Ki |
TKC025887
|
P22303 |
Acetylcholinesterase |
None |
2500 |
nM |
IC50 |
TKC026245
|
P22303 |
Acetylcholinesterase |
None |
10 |
ug |
MIC |
TKC026257
|
P22303 |
Acetylcholinesterase |
None |
1 |
ug |
MIC |
TKC039110
|
P22303 |
Acetylcholinesterase |
None |
4 |
ug |
MIC |
TKC039119
|
P22303 |
Acetylcholinesterase |
None |
4 |
ug |
MIC |
TKC039122
|
P22303 |
Acetylcholinesterase |
None |
4 |
ug |
MIC |
TKC048637
|
P22303 |
Acetylcholinesterase |
None |
29 |
% |
Inhibition |
TKC050924
|
P22303 |
Acetylcholinesterase |
None |
10670 |
nM |
IC50 |
TKC051021
|
P22303 |
Acetylcholinesterase |
None |
22630 |
nM |
IC50 |
TKC051031
|
P22303 |
Acetylcholinesterase |
None |
18350 |
nM |
IC50 |
TKC051032
|
P22303 |
Acetylcholinesterase |
None |
30260 |
nM |
IC50 |
TKC051042
|
P22303 |
Acetylcholinesterase |
None |
17140 |
nM |
IC50 |
TKC056997
|
P22303 |
Acetylcholinesterase |
None |
16270 |
nM |
IC50 |
TKC056998
|
P22303 |
Acetylcholinesterase |
None |
25080 |
nM |
IC50 |
TKC057020
|
P22303 |
Acetylcholinesterase |
None |
31030 |
nM |
IC50 |
TKC061148
|
P22303 |
Acetylcholinesterase |
None |
>30000 |
nM |
IC50 |
TKC062012
|
P22303 |
Acetylcholinesterase |
None |
>30000 |
nM |
IC50 |
TKC062026
|
P22303 |
Acetylcholinesterase |
None |
>30000 |
nM |
IC50 |
TKC062075
|
P22303 |
Acetylcholinesterase |
None |
>30000 |
nM |
IC50 |
TKC063185
|
P22303 |
Acetylcholinesterase |
None |
9980 |
nM |
IC50 |
TKC064964
|
P22303 |
Acetylcholinesterase |
None |
25910 |
nM |
IC50 |
TKC064991
|
P22303 |
Acetylcholinesterase |
None |
9400 |
nM |
IC50 |
TKC068847
|
P22303 |
Acetylcholinesterase |
None |
34 |
% |
Inhibition |
TKC083115
|
P22303 |
Acetylcholinesterase |
None |
26 |
% |
Inhibition |
TKC092147
|
P22303 |
Acetylcholinesterase |
None |
>10 |
ug |
MIC |
TKC092148
|
P22303 |
Acetylcholinesterase |
None |
1 |
ug |
MIC |
TKC092149
|
P22303 |
Acetylcholinesterase |
None |
1 |
ug |
MIC |
TKC092150
|
P22303 |
Acetylcholinesterase |
None |
10 |
ug |
MIC |
TKC092151
|
P22303 |
Acetylcholinesterase |
None |
1 |
ug |
MIC |
TKC092152
|
P22303 |
Acetylcholinesterase |
None |
>10 |
ug |
MIC |
TKC092153
|
P22303 |
Acetylcholinesterase |
None |
>10 |
ug |
MIC |
TKC092154
|
P22303 |
Acetylcholinesterase |
None |
>10 |
ug |
MIC |
TKC092155
|
P22303 |
Acetylcholinesterase |
None |
10 |
ug |
MIC |
TKC092156
|
P22303 |
Acetylcholinesterase |
None |
>10 |
ug |
MIC |
TKC092182
|
P22303 |
Acetylcholinesterase |
None |
>10 |
ug |
MIC |
TKC095827
|
P22303 |
Acetylcholinesterase |
None |
910 |
nM |
IC50 |
TKC101947
|
P22303 |
Acetylcholinesterase |
None |
4 |
ug |
MIC |
TKC103473
|
P22303 |
Acetylcholinesterase |
None |
10 |
ug |
Activity |
TKC107319
|
P22303 |
Acetylcholinesterase |
None |
>100000 |
nM |
Ki |
TKC108605
|
P22303 |
Acetylcholinesterase |
None |
10 |
ug |
Activity |
TKC109315
|
P22303 |
Acetylcholinesterase |
None |
5754 |
nM |
IC50 |
TKC109320
|
P22303 |
Acetylcholinesterase |
None |
181970 |
nM |
IC50 |
TKC109322
|
P22303 |
Acetylcholinesterase |
None |
229087 |
nM |
IC50 |
TKC109330
|
P22303 |
Acetylcholinesterase |
None |
77625 |
nM |
IC50 |
TKC109347
|
P22303 |
Acetylcholinesterase |
None |
33113 |
nM |
IC50 |
TKC109348
|
P22303 |
Acetylcholinesterase |
None |
61660 |
nM |
IC50 |
TKC109364
|
P22303 |
Acetylcholinesterase |
None |
15849 |
nM |
IC50 |
TKC109367
|
P22303 |
Acetylcholinesterase |
None |
30200 |
nM |
IC50 |
TKC109381
|
P22303 |
Acetylcholinesterase |
None |
7079 |
nM |
IC50 |
TKC109383
|
P22303 |
Acetylcholinesterase |
None |
9900 |
nM |
IC50 |
TKC110247
|
P22303 |
Acetylcholinesterase |
None |
>10 |
ug.mL-1 |
IC50 |
TKC112463
|
P22303 |
Acetylcholinesterase |
None |
251189 |
nM |
IC50 |
TKC112467
|
P22303 |
Acetylcholinesterase |
None |
83176 |
nM |
IC50 |
TKC112468
|
P22303 |
Acetylcholinesterase |
None |
48978 |
nM |
IC50 |
TKC112505
|
P22303 |
Acetylcholinesterase |
None |
42658 |
nM |
IC50 |
TKC114542
|
P22303 |
Acetylcholinesterase |
None |
50119 |
nM |
IC50 |
TKC114543
|
P22303 |
Acetylcholinesterase |
None |
70795 |
nM |
IC50 |
TKC114548
|
P22303 |
Acetylcholinesterase |
None |
28000 |
nM |
IC50 |
TKC114549
|
P22303 |
Acetylcholinesterase |
None |
69183 |
nM |
IC50 |
TKC114551
|
P22303 |
Acetylcholinesterase |
None |
28840 |
nM |
IC50 |
TKC114558
|
P22303 |
Acetylcholinesterase |
None |
6457 |
nM |
IC50 |
TKC114561
|
P22303 |
Acetylcholinesterase |
None |
19498 |
nM |
IC50 |
TKC114562
|
P22303 |
Acetylcholinesterase |
None |
6457 |
nM |
IC50 |
TKC114777
|
P22303 |
Acetylcholinesterase |
None |
6166 |
nM |
IC50 |
TKC119401
|
P22303 |
Acetylcholinesterase |
None |
26000 |
nM |
IC50 |
TKC129743
|
P22303 |
Acetylcholinesterase |
None |
>10 |
ug |
Activity |
TKC135978
|
P22303 |
Acetylcholinesterase |
None |
191100 |
nM |
IC50 |
TKC139191
|
P22303 |
Acetylcholinesterase |
None |
>30000 |
nM |
IC50 |
TKC141633
|
P22303 |
Acetylcholinesterase |
None |
24040 |
nM |
IC50 |
TKC142015
|
P22303 |
Acetylcholinesterase |
None |
21100 |
nM |
IC50 |
TKC144380
|
P22303 |
Acetylcholinesterase |
None |
>30000 |
nM |
IC50 |
TKC144901
|
P22303 |
Acetylcholinesterase |
None |
>30000 |
nM |
IC50 |
TKC144904
|
P22303 |
Acetylcholinesterase |
None |
>30000 |
nM |
IC50 |
TKC145173
|
P22303 |
Acetylcholinesterase |
None |
22970 |
nM |
IC50 |
TKC145183
|
P22303 |
Acetylcholinesterase |
None |
18350 |
nM |
IC50 |
TKC147230
|
P22303 |
Acetylcholinesterase |
None |
22310 |
nM |
IC50 |
TKC147240
|
P22303 |
Acetylcholinesterase |
None |
26780 |
nM |
IC50 |
TKC148618
|
P22303 |
Acetylcholinesterase |
None |
21840 |
nM |
IC50 |
TKC150909
|
P22303 |
Acetylcholinesterase |
None |
<10 |
ug.mL-1 |
IC50 |
TKC161356
|
P22303 |
Acetylcholinesterase |
None |
81500 |
nM |
IC50 |
TKC168054
|
P22303 |
Acetylcholinesterase |
None |
1690 |
nM |
IC50 |
TKC174459
|
P22303 |
Acetylcholinesterase |
None |
12260 |
nM |
IC50 |
TKC205554
|
P22303 |
Acetylcholinesterase |
None |
1 |
ug |
MIC |
TKC205771
|
P22303 |
Acetylcholinesterase |
None |
4 |
ug |
MIC |
TKC205772
|
P22303 |
Acetylcholinesterase |
None |
4 |
ug |
MIC |
TKC206567
|
P22303 |
Acetylcholinesterase |
None |
1 |
ug |
Activity |
TKC207001
|
P22303 |
Acetylcholinesterase |
None |
4 |
ug |
MIC |
TKC207197
|
P22303 |
Acetylcholinesterase |
None |
1 |
ug |
MIC |
TKC034640
|
P27338 |
Amine oxidase [flavin-containing] B |
None |
800 |
nM |
Ki |
TKC146423
|
P27338 |
Amine oxidase [flavin-containing] B |
None |
128000 |
nM |
IC50 |
TKC205544
|
P28221 |
5-hydroxytryptamine receptor 1D |
None |
40 |
nM |
Ki |
TKC205544
|
P28221 |
5-hydroxytryptamine receptor 1D |
None |
59 |
nM |
Ki |
TKC205544
|
P28221 |
5-hydroxytryptamine receptor 1D |
None |
15.84 |
nM |
Ki |
TKC205544
|
P28221 |
5-hydroxytryptamine receptor 1D |
None |
19.95 |
nM |
Ki |
TKC206544
|
P28221 |
5-hydroxytryptamine receptor 1D |
None |
>10000 |
nM |
Ki |
TKC205544
|
P28223 |
5-hydroxytryptamine receptor 2A |
None |
>10000 |
nM |
Ki |
TKC205544
|
P28223 |
5-hydroxytryptamine receptor 2A |
None |
252 |
nM |
Ki |
TKC205544
|
P28223 |
5-hydroxytryptamine receptor 2A |
None |
288.4 |
nM |
Ki |
TKC205544
|
P28223 |
5-hydroxytryptamine receptor 2A |
None |
1000 |
nM |
Ki |
TKC206781
|
P28223 |
5-hydroxytryptamine receptor 2A |
None |
1.4 |
nM |
Ki |
TKC206779
|
Q01959 |
Sodium-dependent dopamine transporter |
None |
5486 |
nM |
Ki |