Basic Information

Terpenoid ID TKC026245
Cell line 0
Protein target 7
DiseaseNCIT 0
ORDO 0
ICD 41

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC026245 P388 P-388 2800.0 nM IC50 C21602
TKC026245 A549 5600.0 nM IC50 C3512
TKC026245 HT-29 HT 29; HT29 5600.0 nM IC50 C4349
TKC026245 SK-MEL-28 SK-Mel-28; SK.MEL.28; SK-MEL 28; SK MEL-28; SK MEL 28; SK Mel 28; SKMel-28; SKMEL-28; SK-MEL28; SK-Mel28; SK Mel28; SKMEL28; SKMel28; SKmel28; SKML-28; SK28; AU-Mel; P-36; P36 5600.0 nM IC50 C3510
TKC026245 P388 P-388 2800.0 nM IC50 C21602
TKC026245 A549 5600.0 nM IC50 C3512
TKC026245 HT-29 HT 29; HT29 5600.0 nM IC50 C4349
TKC026245 SK-MEL-28 SK-Mel-28; SK.MEL.28; SK-MEL 28; SK MEL-28; SK MEL 28; SK Mel 28; SKMel-28; SKMEL-28; SK-MEL28; SK-Mel28; SK Mel28; SKMEL28; SKMel28; SKmel28; SKML-28; SK28; AU-Mel; P-36; P36 5600.0 nM IC50 C3510
TKC026245 P388 P-388 3100.0 nM IC50 C21602
TKC026245 A549 6000.0 nM IC50 C3512
TKC026245 HT-29 HT 29; HT29 6000.0 nM IC50 C4349
TKC026245 SK-MEL-28 SK-Mel-28; SK.MEL.28; SK-MEL 28; SK MEL-28; SK MEL 28; SK Mel 28; SKMel-28; SKMEL-28; SK-MEL28; SK-Mel28; SK Mel28; SKMEL28; SKMel28; SKmel28; SKML-28; SK28; AU-Mel; P-36; P36 6000.0 nM IC50 C3510
TKC026245 HaCaT HaCAT; HACAT; Hacat 5.0 % Inhibition
TKC026245 K562 K562; K.562; K 562; KO; GM05372; GM05372E 7300.0 nM IC50 C9110 Orphanet_521
TKC026245 HeLa HELA; Hela; He La; He-La; HeLa-CCL2; Henrietta Lacks cells; Helacyton gartleri 19700.0 nM IC50 C27677
TKC026245 PBMC 3000.0 nM IC50

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC026245 P18031 Tyrosine-protein phosphatase non-receptor type 1 PTPN1 12000 nM IC50
TKC026245 P22303 Acetylcholinesterase ACHE 10 ug MIC
TKC026245 P11597 Cholesteryl ester transfer protein CETP 25000 nM IC50
TKC026245 O42275 Acetylcholinesterase ache 285630 nM IC50
TKC026245 P35354 Prostaglandin G/H synthase 2 PTGS2 2300 nM IC50
TKC026245 P81908 Cholinesterase BCHE 3 % Imax
TKC026245 O77759 Sterol O-acyltransferase 2 SOAT2 14800 nM IC50
TKC026245 O77760 Sterol O-acyltransferase 1 SOAT1 14200 nM IC50
TKC026245 Q60457 Sterol O-acyltransferase 1 SOAT1 12000 nM IC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P18031 PTN1_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
P18031 PTN1_HUMAN Acute diabete complication [ICD-11: 5A2Y]
P18031 PTN1_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
P18031 PTN1_HUMAN Obesity [ICD-11: 5B80-5B81]
P18031 PTN1_HUMAN Ophthalmic devices/implants/grafts injury [ICD-11: PK97]
P18031 PTN1_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
P18031 PTN1_HUMAN Metabolic disorder [ICD-11: 5C50-5D2Z]
P18031 PTN1_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
P22303 ACES_HUMAN Alzheimer disease [ICD-11: 8A20]
P22303 ACES_HUMAN Glaucoma [ICD-11: 9C61]
P22303 ACES_HUMAN Myasthenia gravis [ICD-11: 8C6Y]
P22303 ACES_HUMAN Oesophageal/gastroduodenal disorder [ICD-11: DD90]
P22303 ACES_HUMAN Pediculosis [ICD-11: 1G00]
P22303 ACES_HUMAN Unspecific substance harmful effect [ICD-11: NE6Z]
P22303 ACES_HUMAN Mild neurocognitive disorder [ICD-11: 6D71]
P22303 ACES_HUMAN Parasitic worm infestation [ICD-11: 1F90]
P22303 ACES_HUMAN Dementia [ICD-11: 6D80-6D8Z]
P22303 ACES_HUMAN Pain [ICD-11: MG30-MG3Z]
P22303 ACES_HUMAN Parkinsonism [ICD-11: 8A00]
P22303 ACES_HUMAN Substance abuse [ICD-11: 6C40]
P22303 ACES_HUMAN Lips/oral mucosa miscellaneous disorder [ICD-11: DA02]
P22303 ACES_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P22303 ACES_HUMAN Urinary system disease [ICD-11: GC2Z]
P22303 ACES_HUMAN Neurodegenerative disorder [ICD-11: 8A20-8A23]
P11597 CETP_HUMAN Arterial occlusive disease [ICD-11: BD40]
P11597 CETP_HUMAN Cardiovascular disease [ICD-11: BA00-BE2Z]
P11597 CETP_HUMAN Hyper-lipoproteinaemia [ICD-11: 5C80]
P11597 CETP_HUMAN Myocardial infarction [ICD-11: BA41-BA43]
P11597 CETP_HUMAN Inborn lipid metabolism error [ICD-11: 5C52]
P11597 CETP_HUMAN Chronic arterial occlusive disease [ICD-11: BD4Z]
P11597 CETP_HUMAN Dyslipidemia [ICD-11: 5C80-5C81]
P35354 PGH2_HUMAN Alzheimer disease [ICD-11: 8A20]
P35354 PGH2_HUMAN Chronic pain [ICD-11: MG30]
P35354 PGH2_HUMAN Endometriosis [ICD-11: GA10]
P35354 PGH2_HUMAN Female pelvic pain [ICD-11: GA34]
P35354 PGH2_HUMAN Hyper-lipoproteinaemia [ICD-11: 5C80]
P35354 PGH2_HUMAN Indeterminate colitis [ICD-11: DD72]
P35354 PGH2_HUMAN Knee osteoarthritis [ICD-11: FA01]
P35354 PGH2_HUMAN Migraine [ICD-11: 8A80]
P35354 PGH2_HUMAN Osteoarthritis [ICD-11: FA00-FA05]
P35354 PGH2_HUMAN Pain [ICD-11: MG30-MG3Z]
P35354 PGH2_HUMAN Rheumatoid arthritis [ICD-11: FA20]
P35354 PGH2_HUMAN Tuberculosis [ICD-11: 1B10-1B12]
P35354 PGH2_HUMAN Shoulder lesion [ICD-11: FB53]
P35354 PGH2_HUMAN Soft tissue disorder [ICD-11: FB56]
P35354 PGH2_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P35354 PGH2_HUMAN Asthma [ICD-11: CA23]
P35354 PGH2_HUMAN Gout [ICD-11: FA25]
P35354 PGH2_HUMAN General pain disorder [ICD-11: 8E43]
P35354 PGH2_HUMAN Lupus erythematosus [ICD-11: 4A40]
P35354 PGH2_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
P35354 PGH2_HUMAN Large intestine polyp [ICD-11: DB35]
P35354 PGH2_HUMAN Lung cancer [ICD-11: 2C25]
P35354 PGH2_HUMAN Pancreatic cancer [ICD-11: 2C10]
P35354 PGH2_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
P35354 PGH2_HUMAN Colorectal cancer [ICD-11: 2B91]
P35354 PGH2_HUMAN Fever [ICD-11: MG26]
P35354 PGH2_HUMAN Malignant haematopoietic neoplasm [ICD-11: 2B33]