Basic Information

Terpenoid ID TKC147230
Chirality TKC056990
Cell line 0
Protein target 3
DiseaseNCIT 0
ORDO 0
ICD 16

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC147230 MCF7 5800.0 nM IC50 C4194
TKC147230 MDA-MB-231 MDA_MB_231; MDA-MB 231; MDA.MB.231; MDA MB 231; MDA MB231; MDA Mb231; MDA-MB231; MDAMB-231; MDAMB231; MDA-231; MDA-231P; MDA231; MDA231-BRE; MB231; MD Anderson-Metastatic Breast-231 9700.0 nM IC50 C5214
TKC147230 HeLa HELA; Hela; He La; He-La; HeLa-CCL2; Henrietta Lacks cells; Helacyton gartleri 11000.0 nM IC50 C27677
TKC147230 K562 K562; K.562; K 562; KO; GM05372; GM05372E 80900.0 nM IC50 C9110 Orphanet_521
TKC147230 PC-3 PC3; PC.3 105800.0 nM IC50 C4863

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC147230 P06276 Cholinesterase BCHE >200000 nM IC50
TKC147230 P22303 Acetylcholinesterase ACHE 22310 nM IC50
TKC147230 P28700 Retinoic acid receptor RXR-alpha Rxra 2500 nM EC50
TKC147230 Q1W675 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 16800 nM IC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P06276 CHLE_HUMAN Pain [ICD-11: MG30-MG3Z]
P06276 CHLE_HUMAN Tonus and reflex abnormality [ICD-11: MB47]
P06276 CHLE_HUMAN Alzheimer disease [ICD-11: 8A20]
P06276 CHLE_HUMAN Mild neurocognitive disorder [ICD-11: 6D71]
P06276 CHLE_HUMAN Eexposure to noxious substances harmful effect [ICD-11: NE61]
P06276 CHLE_HUMAN Toxicity [ICD-11: N.A.]
P06276 CHLE_HUMAN Unspecific substance harmful effect [ICD-11: NE6Z]
P22303 ACES_HUMAN Alzheimer disease [ICD-11: 8A20]
P22303 ACES_HUMAN Glaucoma [ICD-11: 9C61]
P22303 ACES_HUMAN Myasthenia gravis [ICD-11: 8C6Y]
P22303 ACES_HUMAN Oesophageal/gastroduodenal disorder [ICD-11: DD90]
P22303 ACES_HUMAN Pediculosis [ICD-11: 1G00]
P22303 ACES_HUMAN Unspecific substance harmful effect [ICD-11: NE6Z]
P22303 ACES_HUMAN Mild neurocognitive disorder [ICD-11: 6D71]
P22303 ACES_HUMAN Parasitic worm infestation [ICD-11: 1F90]
P22303 ACES_HUMAN Dementia [ICD-11: 6D80-6D8Z]
P22303 ACES_HUMAN Pain [ICD-11: MG30-MG3Z]
P22303 ACES_HUMAN Parkinsonism [ICD-11: 8A00]
P22303 ACES_HUMAN Substance abuse [ICD-11: 6C40]
P22303 ACES_HUMAN Lips/oral mucosa miscellaneous disorder [ICD-11: DA02]
P22303 ACES_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P22303 ACES_HUMAN Urinary system disease [ICD-11: GC2Z]
P22303 ACES_HUMAN Neurodegenerative disorder [ICD-11: 8A20-8A23]