Terpenome defines as all terpenoid-like and terpenoid-derived compounds, including the terpenoids, steroids and their derivatives. Terpenoids represent the most chemically and structurally diverse family of natural products. There is a growing concern about terpenome by the Pharmaceutical Chemist because of their huge medicinal value, with artemisinin and paclitaxel for representative. TeroKit is a webserver-based multi-scale toolkit conducive to the research of terpenome. It contains databases with annotated data of more than 180,000 terpenome compounds (TeroMOL), 4400 terpene synthases (TeroTPS), 700 cytochrome P450 monooxygenases (TeroP450), 1300 glycosyltransferases (TeroGTs) and 6900 other modification enzymes, which are further integrated to the terpenome metabolic network (TeroMAP). TeroKit provides the online retrieval and analysis of chemical space, biological activities and biosynthetic pathways for terpenome.