Basic Information

Terpenoid ID TKC197337
Chirality TKC197335
Cell line 0
Protein target 12
DiseaseNCIT 0
ORDO 0
ICD 30

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC197337 P388 P-388 42657952.0 nM IC50 C21602
TKC197337 HEK293 76.0 nM IC50
TKC197337 HeLa HELA; Hela; He La; He-La; HeLa-CCL2; Henrietta Lacks cells; Helacyton gartleri 1.0 nM IC50 C27677
TKC197337 L1210 L 1210; L-1210; Leukemic 1210; Leukemia 1210; Leukemia L1210 1.0 ug.mL-1 IC50 C21604

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC197337 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 TDP1 33 nM Potency
TKC197337 O75874 Isocitrate dehydrogenase [NADP] cytoplasmic IDH1 7 nM Potency
TKC197337 P43220 Glucagon-like peptide 1 receptor GLP1R 316 nM Potency
TKC197337 Q03431 Parathyroid hormone/parathyroid hormone-related peptide receptor PTH1R 44668 nM Potency
TKC197337 Q16236 Nuclear factor erythroid 2-related factor 2 NFE2L2 2060 nM Potency
TKC197337 O75496 Geminin GMNN 2593 nM Potency
TKC197337 Q96QE3 ATPase family AAA domain-containing protein 5 ATAD5 231 nM Potency
TKC197337 P63096 Guanine nucleotide-binding protein G GNAI1 7943 nM Potency
TKC197337 P02791 Ferritin light chain FTL 14125 nM Potency
TKC197337 Q9F4F7 4'-phosphopantetheinyl transferase ffp ffp 11220 nM Potency
TKC197337 P51450 Nuclear receptor ROR-gamma Rorc 8913 nM Potency
TKC197337 O15118 NPC intracellular cholesterol transporter 1 NPC1 25 nM Potency
TKC197337 P02550 Tubulin alpha-1A chain TUBA1A >25 uM ED50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
O75874 IDHC_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
O75874 IDHC_HUMAN Liver cancer [ICD-11: 2C12]
O75874 IDHC_HUMAN Malignant haematopoietic neoplasm [ICD-11: 2B33]
O75874 IDHC_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
O75874 IDHC_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
O75874 IDHC_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P43220 GLP1R_HUMAN Cardiovascular disease [ICD-11: BA00-BE2Z]
P43220 GLP1R_HUMAN Obesity [ICD-11: 5B80-5B81]
P43220 GLP1R_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
P43220 GLP1R_HUMAN Type-1/2 diabete [ICD-11: 5A10-5A11]
P43220 GLP1R_HUMAN Acute diabete complication [ICD-11: 5A2Y]
P43220 GLP1R_HUMAN Diabetes mellitus [ICD-11: 5A10]
P43220 GLP1R_HUMAN Dyspepsia [ICD-11: MD92]
P43220 GLP1R_HUMAN Irritable bowel syndrome [ICD-11: DD91]
P43220 GLP1R_HUMAN Intracranial injury [ICD-11: NA07]
P43220 GLP1R_HUMAN Non-alcoholic fatty liver disease [ICD-11: DB92]
Q03431 PTH1R_HUMAN Low bone mass disorder [ICD-11: FB83]
Q03431 PTH1R_HUMAN Hypo-parathyroidism [ICD-11: 5A50]
Q16236 NF2L2_HUMAN Ataxic disorder [ICD-11: 8A03]
Q16236 NF2L2_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
Q16236 NF2L2_HUMAN Glaucoma [ICD-11: 9C61]
Q16236 NF2L2_HUMAN Lung cancer [ICD-11: 2C25]
Q16236 NF2L2_HUMAN Macular degeneration [ICD-11: 9B75]
Q16236 NF2L2_HUMAN Melanoma [ICD-11: 2C30]
Q16236 NF2L2_HUMAN Mental/behavioural/neurodevelopmental disorder [ICD-11: 6E20-6E8Z]
Q16236 NF2L2_HUMAN Pulmonary hypertension [ICD-11: BB01]
Q16236 NF2L2_HUMAN Subarachnoid haemorrhage [ICD-11: 8B01]
Q16236 NF2L2_HUMAN Urinary system clinical sympton [ICD-11: MF8Y]
Q16236 NF2L2_HUMAN Non-alcoholic fatty liver disease [ICD-11: DB92]
Q16236 NF2L2_HUMAN Alpha-1-antitrypsin deficiency [ICD-11: 5C5A]
Q16236 NF2L2_HUMAN Motor neuron disease [ICD-11: 8B60]
Q16236 NF2L2_HUMAN Multiple sclerosis [ICD-11: 8A40]