Basic Information

Terpenoid ID TKC151321
Chirality TKC039868
Cell line 0
Protein target 8
DiseaseNCIT 0
ORDO 0
ICD 3

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC151321 FM3A FM3A clone 28; FM3A cl28 10.0 nM EC50 C21678
TKC151321 P388 P-388 28.0 ug.mL-1 IC50 C21602
TKC151321 KB KB (HeLa derivative); HeLa-KB; Strain KB 16.0 ug.mL-1 IC50 C27677
TKC151321 SK-OV-3 SKOV-3; SK-OV3; SK.OV.3; SKOV3; Skov3; SKO3 14300.0 nM IC50 C7978
TKC151321 Vero VERO; VeroCCL81; Vero 81; Vero-81; Verda reno 5.0 ug.mL-1 IC50
TKC151321 L6 L-6; L-6 myoblast 170000.0 nM IC50
TKC151321 LLC-PK1 LLC-PK(1); LLC-PK-1; LLC PK-1; LLc-PK1; LLC PK1; LLCPK1; Lilly Laboratories Culture-Porcine Kidney 1 1.0 ug.mL-1 IC50
TKC151321 A549 15200.0 nM IC50 C3512
TKC151321 SK-MEL-2 SK-Mel-2; SK-Mel 2; SK-mel-2; SK-MEL2; SK.MEL.2; SK Mel 2; SK MEL 2; SKMEL-2; SKMEL2; SKmel2; SK-ML2; SKml2 12900.0 nM IC50 C3224
TKC151321 XF498 XF-498; XF498 16200.0 nM IC50 C3058 Orphanet_360
TKC151321 HCT-15 HCT-15; HCT.15; HCT15 17200.0 nM IC50 C4349
TKC151321 SW-620 SW-620; SW 620; SW.620 35.0 % GI C4349
TKC151321 IGROV-1 Igrov-1; IGROV 1; IGR-OV1; IGROV1; Igrov1; IGR.OV1; IGROV; OV1/P; OV1/p; OV1-P 26.0 % GI C7979 Orphanet_454723
TKC151321 IMR-32 IMR 32; IMR32; Institute for Medical Research-32; GM03320; GM3320C; GM03320D; AG03320; AG3320 23.0 % GI C3270 Orphanet_635
TKC151321 CCRF-CEM CCRF/CEM; CCRFCEM; CCRF.CEM; CCRF CEM; CCRF; CEM; CEM-CCRF; CEM-CCRF (CAMR); CCRF/CEM/0; CEM/0; CEM-0; CCRF-CEM/S; GM03671; GM03671C 36900.0 nM IC50 C7953 Orphanet_99861
TKC151321 ADR5000 cell line CCRF ADR5000; CCRF-ADR5000; CEM/ADR5000; CEM/ADR 5000; CEM-ADR5000; CEM ADR5000; ADR5000 26900.0 nM IC50 C7953 Orphanet_99861

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC151321 P00352 Retinal dehydrogenase 1 ALDH1A1 25119 nM Potency
TKC151321 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 TDP1 4110 nM Potency
TKC151321 O94782 Ubiquitin carboxyl-terminal hydrolase 1 USP1 251 nM Potency
TKC151321 Q13148 TAR DNA-binding protein 43 TARDBP 7943 nM Potency
TKC151321 Q96QE3 ATPase family AAA domain-containing protein 5 ATAD5 32629 nM Potency
TKC151321 P02791 Ferritin light chain FTL 35481 nM Potency
TKC151321 Q194T2 Non-structural protein 1 NS1 1413 nM Potency
TKC151321 P28272 Dihydroorotate dehydrogenase URA1 >10000 nM IC50
TKC151321 Q54A96 Dihydroorotate dehydrogenase dhod >10000 nM IC50
TKC151321 P62343 Calcium-dependent protein kinase 1 CDPK1 28 nM EC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
O94782 UBP1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
Q13148 TADBP_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
Q13148 TADBP_HUMAN Alzheimer disease [ICD-11: 8A20]