Basic Information

Terpenoid ID TKC150907
Chirality TKC135961
Cell line 2
Protein target 1
DiseaseNCIT 2
ORDO 1
ICD 27

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC150907 NIH3T3 NIH/3T3; NIH-3T3; NIH3T3; 3T3; 3T3NIH; 3T3-Swiss; Swiss-3T3; Swiss/3T3; Swiss 3T3; Swiss3T3 8.0 ug.mL-1 GI50
TKC150907 NCI-H460 NCI.H460; H460; H-460; NCIH460; NCI-HUT-460; NCI-460 32800.0 nM GI50 C4450
TKC150907 ME-180 Me-180; ME 180; ME180 18200.0 nM GI50 C27676 Orphanet_213767
TKC150907 DU-145 DU-145; Du-145; DU 145; DU_145; DU.145; Duke University 145 25800.0 nM GI50 C4863
TKC150907 MCF7 30000.0 nM GI50 C4194
TKC150907 M14 M14-MEL; UCLA-SO-M14; UCLA SO M14; UCLA-SO-14; UCLASO-M14; Melanoma 14; M-14 15100.0 nM GI50 C3802
TKC150907 HT-29 HT 29; HT29 28900.0 nM GI50 C4349
TKC150907 PC-3 PC3; PC.3 28500.0 nM GI50 C4863
TKC150907 K562 K562; K.562; K 562; KO; GM05372; GM05372E 40500.0 nM GI50 C9110 Orphanet_521

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC150907 P35354 Prostaglandin G/H synthase 2 PTGS2 <30 % Inhibition

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P35354 PGH2_HUMAN Alzheimer disease [ICD-11: 8A20]
P35354 PGH2_HUMAN Chronic pain [ICD-11: MG30]
P35354 PGH2_HUMAN Endometriosis [ICD-11: GA10]
P35354 PGH2_HUMAN Female pelvic pain [ICD-11: GA34]
P35354 PGH2_HUMAN Hyper-lipoproteinaemia [ICD-11: 5C80]
P35354 PGH2_HUMAN Indeterminate colitis [ICD-11: DD72]
P35354 PGH2_HUMAN Knee osteoarthritis [ICD-11: FA01]
P35354 PGH2_HUMAN Migraine [ICD-11: 8A80]
P35354 PGH2_HUMAN Osteoarthritis [ICD-11: FA00-FA05]
P35354 PGH2_HUMAN Pain [ICD-11: MG30-MG3Z]
P35354 PGH2_HUMAN Rheumatoid arthritis [ICD-11: FA20]
P35354 PGH2_HUMAN Tuberculosis [ICD-11: 1B10-1B12]
P35354 PGH2_HUMAN Shoulder lesion [ICD-11: FB53]
P35354 PGH2_HUMAN Soft tissue disorder [ICD-11: FB56]
P35354 PGH2_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P35354 PGH2_HUMAN Asthma [ICD-11: CA23]
P35354 PGH2_HUMAN Gout [ICD-11: FA25]
P35354 PGH2_HUMAN General pain disorder [ICD-11: 8E43]
P35354 PGH2_HUMAN Lupus erythematosus [ICD-11: 4A40]
P35354 PGH2_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
P35354 PGH2_HUMAN Large intestine polyp [ICD-11: DB35]
P35354 PGH2_HUMAN Lung cancer [ICD-11: 2C25]
P35354 PGH2_HUMAN Pancreatic cancer [ICD-11: 2C10]
P35354 PGH2_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
P35354 PGH2_HUMAN Colorectal cancer [ICD-11: 2B91]
P35354 PGH2_HUMAN Fever [ICD-11: MG26]
P35354 PGH2_HUMAN Malignant haematopoietic neoplasm [ICD-11: 2B33]