Basic Information

Terpenoid ID TKC149926
Chirality TKC032619
Cell line 0
Protein target 5
DiseaseNCIT 0
ORDO 0
ICD 27

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC149926 HEK293 8500.0 nM IC50
TKC149926 MCF7 5900.0 nM IC50 C4194
TKC149926 C6 C-6; C 6; RGC-6; RGC6; RGc6 3900.0 nM IC50 C64069

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC149926 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 TDP1 2372 nM Potency
TKC149926 P29477 Nitric oxide synthase, inducible Nos2 8000 nM IC50
TKC149926 P0DTD1 Replicase polyprotein 1ab rep 9 % Inhibition
TKC149926 P35354 Prostaglandin G/H synthase 2 PTGS2 800 nM IC50
TKC149926 P0A749 UDP-N-acetylglucosamine 1-carboxyvinyltransferase murA >50000 nM IC50
TKC149926 Q9HVW7 UDP-N-acetylglucosamine 1-carboxyvinyltransferase murA 27800 nM IC50
TKC149926 P14842 5-hydroxytryptamine receptor 2A Htr2a 100000 nM Ki

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P35354 PGH2_HUMAN Alzheimer disease [ICD-11: 8A20]
P35354 PGH2_HUMAN Chronic pain [ICD-11: MG30]
P35354 PGH2_HUMAN Endometriosis [ICD-11: GA10]
P35354 PGH2_HUMAN Female pelvic pain [ICD-11: GA34]
P35354 PGH2_HUMAN Hyper-lipoproteinaemia [ICD-11: 5C80]
P35354 PGH2_HUMAN Indeterminate colitis [ICD-11: DD72]
P35354 PGH2_HUMAN Knee osteoarthritis [ICD-11: FA01]
P35354 PGH2_HUMAN Migraine [ICD-11: 8A80]
P35354 PGH2_HUMAN Osteoarthritis [ICD-11: FA00-FA05]
P35354 PGH2_HUMAN Pain [ICD-11: MG30-MG3Z]
P35354 PGH2_HUMAN Rheumatoid arthritis [ICD-11: FA20]
P35354 PGH2_HUMAN Tuberculosis [ICD-11: 1B10-1B12]
P35354 PGH2_HUMAN Shoulder lesion [ICD-11: FB53]
P35354 PGH2_HUMAN Soft tissue disorder [ICD-11: FB56]
P35354 PGH2_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P35354 PGH2_HUMAN Asthma [ICD-11: CA23]
P35354 PGH2_HUMAN Gout [ICD-11: FA25]
P35354 PGH2_HUMAN General pain disorder [ICD-11: 8E43]
P35354 PGH2_HUMAN Lupus erythematosus [ICD-11: 4A40]
P35354 PGH2_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
P35354 PGH2_HUMAN Large intestine polyp [ICD-11: DB35]
P35354 PGH2_HUMAN Lung cancer [ICD-11: 2C25]
P35354 PGH2_HUMAN Pancreatic cancer [ICD-11: 2C10]
P35354 PGH2_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
P35354 PGH2_HUMAN Colorectal cancer [ICD-11: 2B91]
P35354 PGH2_HUMAN Fever [ICD-11: MG26]
P35354 PGH2_HUMAN Malignant haematopoietic neoplasm [ICD-11: 2B33]
P0A749 MURA_ECOLI Bacterial infection [ICD-11: 1A00-1C4Z]
P0A749 MURA_ECOLI Gram-positive bacterial infection [ICD-11: 1B74-1F40]