Basic Information

Terpenoid ID TKC138731
Chirality TKC146774
Cell line 0
Protein target 2
DiseaseNCIT 0
ORDO 0
ICD 7

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC138731 A549 22100.0 nM IC50 C3512
TKC138731 SK-OV-3 SKOV-3; SK-OV3; SK.OV.3; SKOV3; Skov3; SKO3 41730.0 nM IC50 C7978
TKC138731 SK-MEL-2 SK-Mel-2; SK-Mel 2; SK-mel-2; SK-MEL2; SK.MEL.2; SK Mel 2; SK MEL 2; SKMEL-2; SKMEL2; SKmel2; SK-ML2; SKml2 19520.0 nM IC50 C3224
TKC138731 HCT-15 HCT-15; HCT.15; HCT15 12530.0 nM IC50 C4349
TKC138731 RAW264.7 RAW264 27700.0 nM IC50 C21604
TKC138731 BV-2 BV2 21600.0 nM IC50

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC138731 P18031 Tyrosine-protein phosphatase non-receptor type 1 PTPN1 14330 nM IC50
TKC138731 P00489 Glycogen phosphorylase, muscle form PYGM 144000 nM IC50
TKC138731 P00489 Glycogen phosphorylase, muscle form PYGM 144000 nM IC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P18031 PTN1_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
P18031 PTN1_HUMAN Acute diabete complication [ICD-11: 5A2Y]
P18031 PTN1_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
P18031 PTN1_HUMAN Obesity [ICD-11: 5B80-5B81]
P18031 PTN1_HUMAN Ophthalmic devices/implants/grafts injury [ICD-11: PK97]
P18031 PTN1_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
P18031 PTN1_HUMAN Metabolic disorder [ICD-11: 5C50-5D2Z]
P18031 PTN1_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]