Basic Information

Terpenoid ID TKC046453
Chirality TKC137345
Cell line 51
Protein target 0
DiseaseNCIT 52
ORDO 16
ICD 0

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC046453 HL-60 HL 60; HL.60 HL60; Human Leukemia-60 140.0 nM GI50 C9154 Orphanet_519
TKC046453 MOLT-4 Molt-4; MOLT 4; Molt 4; MOLT.4; MOLT4; Molt4; GM02219; GM02219C; GM2219C; GM02219D 980.0 nM GI50 C9142 Orphanet_99861
TKC046453 A549 1450.0 nM GI50 C3512
TKC046453 KM12 KM-12; KM.12 940.0 nM GI50 C4910
TKC046453 786-0 786-o; 786O; 786-0; 786.O; 786-O RCC; RCC 786-O; RCC_7860; RCC 7860; 7860; 786-0WT 610.0 nM GI50 C9385 Orphanet_217071
TKC046453 BT-549 BT 549; BT.549; BT549 960.0 nM GI50 C4194
TKC046453 CCRF-CEM CCRF/CEM; CCRFCEM; CCRF.CEM; CCRF CEM; CCRF; CEM; CEM-CCRF; CEM-CCRF (CAMR); CCRF/CEM/0; CEM/0; CEM-0; CCRF-CEM/S; GM03671; GM03671C 200.0 nM GI50 C7953 Orphanet_99861
TKC046453 SR SR-786; SR786 1130.0 nM GI50 C37193 Orphanet_300895
TKC046453 EKVX 1170.0 nM GI50 C3512
TKC046453 HOP-62 HOP 62; Hop 62; HOP.62; HOP62; Hop62; Hopkins-62 1050.0 nM GI50 C3512
TKC046453 HOP-92 HOP 92; HOP.92; HOP92; Hop92; Hopkins-92 290.0 nM GI50 C2926
TKC046453 NCI-H226 NCI.H226; NCI H226; H226; H-226; HUT-226; HUT 226; NCIH226 110.0 nM GI50 C45662 Orphanet_50251
TKC046453 NCI-H23 NCI.H23; NCI H23; H-23; H23; NCIH23 2020.0 nM GI50 C3512
TKC046453 NCI-H322M NCI.H322M; H322M; H-322M; H-322m 1910.0 nM GI50 C2923
TKC046453 NCI-H460 NCI.H460; H460; H-460; NCIH460; NCI-HUT-460; NCI-460 1590.0 nM GI50 C4450
TKC046453 NCI-H522 NCI.H522; H522; H-522; NCI-522; NCI522; NCIH522 120.0 nM GI50 C3512
TKC046453 COLO 205 Colo 205; CoLo 205; COLO-205; Colo-205; COLO.205; Colo205; COLO205; Co 205; Colorado 205 2180.0 nM GI50 C4349
TKC046453 HCC 2998 HCC-2998; HCC.2998; HCC 2998; Hamon Cancer Center 2998 1550.0 nM GI50 C4349
TKC046453 HCT-116 HCT-116; HCT.116; HCT_116; HCT116; HCT116wt; CoCL2 1800.0 nM GI50 C4910
TKC046453 HCT-15 HCT-15; HCT.15; HCT15 1890.0 nM GI50 C4349
TKC046453 HT-29 HT 29; HT29 1570.0 nM GI50 C4349
TKC046453 SW-620 SW-620; SW 620; SW.620 1570.0 nM GI50 C4349
TKC046453 SF-295 SF-295; SF.295; SF 295 1460.0 nM GI50 C3058 Orphanet_360
TKC046453 SF-539 SF-539; SF-539 BT; SF.539; SF 539 1610.0 nM GI50 C3796 Orphanet_251576
TKC046453 SNB-75 SNB.75; SNB75; Surgical Neurology Branch-75 1080.0 nM GI50 C3058 Orphanet_360
TKC046453 U-251 U-251 MG; U-251-MG; U-251_MG; U251-MG; U251MG; U-251; U251; U251n; U251N; 251 MG; 251MG; 251 MG(6) 1730.0 nM GI50 C60781 Orphanet_94
TKC046453 Malme-3M MALME-3M; MALME 3M; Malme-3 M; MALME.3M; Malme3M; MALME3M; Malme-3 Monolayer 1200.0 nM GI50 C3224
TKC046453 M14 M14-MEL; UCLA-SO-M14; UCLA SO M14; UCLA-SO-14; UCLASO-M14; Melanoma 14; M-14 3290.0 nM GI50 C3802
TKC046453 SK-MEL-2 SK-Mel-2; SK-Mel 2; SK-mel-2; SK-MEL2; SK.MEL.2; SK Mel 2; SK MEL 2; SKMEL-2; SKMEL2; SKmel2; SK-ML2; SKml2 2170.0 nM GI50 C3224
TKC046453 SK-MEL-28 SK-Mel-28; SK.MEL.28; SK-MEL 28; SK MEL-28; SK MEL 28; SK Mel 28; SKMel-28; SKMEL-28; SK-MEL28; SK-Mel28; SK Mel28; SKMEL28; SKMel28; SKmel28; SKML-28; SK28; AU-Mel; P-36; P36 3310.0 nM GI50 C3510
TKC046453 SK-MEL-5 SK-Mel-5; SK MEL 5; SK.MEL.5; SK-MEL5; SKMel-5; SKMEL-5; SKMEL5; SKMel5; SKmel5; AA-Mel 2680.0 nM GI50 C3510
TKC046453 UACC-257 UACC 257; UACC.257; UACC257; University of Arizona Cell Culture-257 3680.0 nM GI50 C3224
TKC046453 UACC-62 UACC 62; UACC.62; UACC62; University of Arizona Cell Culture-62 2320.0 nM GI50 C3224
TKC046453 IGROV-1 Igrov-1; IGROV 1; IGR-OV1; IGROV1; Igrov1; IGR.OV1; IGROV; OV1/P; OV1/p; OV1-P 120.0 nM GI50 C7979 Orphanet_454723
TKC046453 OVCAR-3 Ovcar-3; OVCAR 3; OVCAR.3; NIH:OVCAR-3; NIH:Ovcar-3; NIH:OVCAR3; NIH-OVCAR-3; NIHOVCAR3; OVCAR3; Ovcar3 1850.0 nM GI50 C105555
TKC046453 OVCAR-4 OVCAR 4; NIH:OVCAR-4; NIH:OVCAR4; OVCAR.4; OVCAR4; Ovcar4 1890.0 nM GI50 C105555
TKC046453 OVCAR-5 OVCAR 5; NIH:OVCAR-5; OVCAR.5; OVCAR5; Ovcar5; OVCA5 1740.0 nM GI50 C105555
TKC046453 OVCAR-8 OVCAR 8; NIH:OVCAR-8; OVCAR8; Ovcar8; OVCAR.8; OVCA8 1570.0 nM GI50 C105555
TKC046453 SK-OV-3 SKOV-3; SK-OV3; SK.OV.3; SKOV3; Skov3; SKO3 1570.0 nM GI50 C7978
TKC046453 A498 A498 1930.0 nM GI50 C9385 Orphanet_217071
TKC046453 ACHN 1380.0 nM GI50 C6975 Orphanet_319298
TKC046453 CAKI-1 CAL 1; Centre Antoine Lacassagne-1 1760.0 nM GI50 C3224
TKC046453 RXF 393 RXF393L; RXF-393 L; RXF-393; RXF 393; RXF.393; RXF393; RXF 393NL 1220.0 nM GI50 C9385 Orphanet_217071
TKC046453 SN12C SN-12C 1780.0 nM GI50 C9385 Orphanet_217071
TKC046453 UO-31 UO.31; UO31; U031 1220.0 nM GI50 C9385 Orphanet_217071
TKC046453 PC-3 PC3; PC.3 1690.0 nM GI50 C4863
TKC046453 MCF7 1780.0 nM GI50 C4194
TKC046453 MDA-MB-231 MDA_MB_231; MDA-MB 231; MDA.MB.231; MDA MB 231; MDA MB231; MDA Mb231; MDA-MB231; MDAMB-231; MDAMB231; MDA-231; MDA-231P; MDA231; MDA231-BRE; MB231; MD Anderson-Metastatic Breast-231 3710.0 nM GI50 C5214
TKC046453 MDA-MB-435 MDA-MB435; MDAMB435; MDA.MB.435; MDA-435; MDA 435; MDA435; MD Anderson-Metastatic Breast-435 1980.0 nM GI50 C3802
TKC046453 MDA-N MDAN 1830.0 nM GI50 C3802
TKC046453 T47D 2000.0 nM GI50 C4194
TKC046453 L1210 L 1210; L-1210; Leukemic 1210; Leukemia 1210; Leukemia L1210 230.0 Zone units Activity C21604
TKC046453 P388 P-388 230.0 Zone units Activity C21602
TKC046453 MC-38 MCA-38; MCA 38; MCA38; MC38; Mouse Colon 38; Murine Carcinoma-38; Colon 38; Colon-38; Colon38; C38 180.0 Zone units Activity C120044
TKC046453 CX-1 HT-29/CX-1; CX1 220.0 Zone units Activity C4349

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11