Basic Information

Terpenoid ID TKC016420
Chirality TKC016414
Cell line 0
Protein target 7
DiseaseNCIT 0
ORDO 0
ICD 14

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC016420 H4 H-4 32959.0 nM EC50 C60781 Orphanet_94
TKC016420 HL-60 HL 60; HL.60 HL60; Human Leukemia-60 6300.0 nM GI50 C9154 Orphanet_519

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC016420 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 TDP1 3663 nM Potency
TKC016420 Q16236 Nuclear factor erythroid 2-related factor 2 NFE2L2 35481 nM Potency
TKC016420 Q99700 Ataxin-2 ATXN2 31623 nM Potency
TKC016420 O75496 Geminin GMNN 7308 nM Potency
TKC016420 P01215 Glycoprotein hormones alpha chain CGA 28184 nM Potency
TKC016420 P83916 Chromobox protein homolog 1 CBX1 56234 nM Potency
TKC016420 Q96QE3 ATPase family AAA domain-containing protein 5 ATAD5 16354 nM Potency

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
Q16236 NF2L2_HUMAN Ataxic disorder [ICD-11: 8A03]
Q16236 NF2L2_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
Q16236 NF2L2_HUMAN Glaucoma [ICD-11: 9C61]
Q16236 NF2L2_HUMAN Lung cancer [ICD-11: 2C25]
Q16236 NF2L2_HUMAN Macular degeneration [ICD-11: 9B75]
Q16236 NF2L2_HUMAN Melanoma [ICD-11: 2C30]
Q16236 NF2L2_HUMAN Mental/behavioural/neurodevelopmental disorder [ICD-11: 6E20-6E8Z]
Q16236 NF2L2_HUMAN Pulmonary hypertension [ICD-11: BB01]
Q16236 NF2L2_HUMAN Subarachnoid haemorrhage [ICD-11: 8B01]
Q16236 NF2L2_HUMAN Urinary system clinical sympton [ICD-11: MF8Y]
Q16236 NF2L2_HUMAN Non-alcoholic fatty liver disease [ICD-11: DB92]
Q16236 NF2L2_HUMAN Alpha-1-antitrypsin deficiency [ICD-11: 5C5A]
Q16236 NF2L2_HUMAN Motor neuron disease [ICD-11: 8B60]
Q16236 NF2L2_HUMAN Multiple sclerosis [ICD-11: 8A40]