Basic Information

Terpenoid ID TKC006014
Chirality TKC079980
Cell line 16
Protein target 2
DiseaseNCIT 15
ORDO 3
ICD 0

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC006014 Panel NCI-60 (60 carcinoma cell lines) 453.0 nM GI50
TKC006014 SW480 SW-480; SW 480; SW480E 7200.0 nM IC50 C4349
TKC006014 HL-60 HL 60; HL.60 HL60; Human Leukemia-60 3900.0 nM IC50 C9154 Orphanet_519
TKC006014 Bel-7402 Bel-7402; BEL 7402; Bel 7402; BEL7402; Bel7402 7360.0 nM IC50 C27677
TKC006014 A549 7200.0 nM IC50 C3512
TKC006014 B16 B-16; B16 melanoma; B16 subline B78; B78 26150.0 nM IC50 C21790
TKC006014 H22 Hepatoma-22; Hepatoma 22 43.0 % Inhibition C38756
TKC006014 HEp-2 Hep-2; HEP-2; Hep2 (HeLa derivative); HEp-2/HeLa; Hep 2; Hep2; HEp2; HEP2; H.Ep.-2; H.Ep. #2; H.Ep. No. 2; Hep II; Human Epidermoid carcinoma #2; Human Epithelioma-2 89.0 % Activity C27677
TKC006014 MDA-MB-231 MDA_MB_231; MDA-MB 231; MDA.MB.231; MDA MB 231; MDA MB231; MDA Mb231; MDA-MB231; MDAMB-231; MDAMB231; MDA-231; MDA-231P; MDA231; MDA231-BRE; MB231; MD Anderson-Metastatic Breast-231 2380.0 nM IC50 C5214
TKC006014 HepG2 3660.0 nM IC50 C3728 Orphanet_449
TKC006014 MGC-803 MGC803; MGc80-3 3570.0 nM IC50 C5248
TKC006014 K562 K562; K.562; K 562; KO; GM05372; GM05372E 4590.0 nM IC50 C9110 Orphanet_521
TKC006014 MCF7 4360.0 nM IC50 C4194
TKC006014 HeLa HELA; Hela; He La; He-La; HeLa-CCL2; Henrietta Lacks cells; Helacyton gartleri 17800.0 nM IC50 C27677
TKC006014 HMEC 5600.0 nM IC50
TKC006014 SW-620 SW-620; SW 620; SW.620 6260.0 nM IC50 C4349
TKC006014 NCI-H460 NCI.H460; H460; H-460; NCIH460; NCI-HUT-460; NCI-460 17140.0 nM IC50 C4450
TKC006014 PC-3 PC3; PC.3 10970.0 nM IC50 C4863
TKC006014 L02 L02; LO2; HL-7702; HL7702; Liver-02; Human Liver-7702 18940.0 nM IC50 C27677
TKC006014 EC9706 Ec9706; EC-9706 38420.0 nM IC50 C4024 Orphanet_99977
TKC006014 ECa-109 cell line 31780.0 nM IC50
TKC006014 HGC-27 HGC 27; HGC27 32030.0 nM IC50 C4911

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC006014 O42275 Acetylcholinesterase ache 25 % Inhibition
TKC006014 P81908 Cholinesterase BCHE 0 % Inhibition

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11