Basic Information

Terpenoid ID TKC206874
Chirality TKC117619
Cell line 0
Protein target 1
DiseaseNCIT 0
ORDO 0
ICD 0

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC206874 WI-38 VA13 WI 38 VA13 subline 2RA; WI 38 VA-13 subline 2RA; WI 38VA13 subline 2RA; WI-38 VA13 sub 2 RA; WI38-VA13 subline 2RA; WI38 VA13/2RA; WI38VA13/2RA; VA13 2RA; WI-38 VA13; WI 38 VA 13; WI38-VA13; WI38/VA13; WI38VA13; VA-13; VA13; AG07217; AG7217 170000.0 nM IC50
TKC206874 HepG2 1500000.0 nM IC50 C3728 Orphanet_449
TKC206874 A549 310.0 nM IC50 C3512
TKC206874 WI-38 VA13 WI 38 VA13 subline 2RA; WI 38 VA-13 subline 2RA; WI 38VA13 subline 2RA; WI-38 VA13 sub 2 RA; WI38-VA13 subline 2RA; WI38 VA13/2RA; WI38VA13/2RA; VA13 2RA; WI-38 VA13; WI 38 VA 13; WI38-VA13; WI38/VA13; WI38VA13; VA-13; VA13; AG07217; AG7217 240000.0 nM IC50
TKC206874 HepG2 820000.0 nM IC50 C3728 Orphanet_449
TKC206874 A549 570.0 nM IC50 C3512
TKC206874 HPBALL HPB/ALL; HPBALL; FCCH1018 14.0 nM IC50 C7953 Orphanet_99861
TKC206874 HEK293 28.0 nM IC50
TKC206874 CCRF-CEM CCRF/CEM; CCRFCEM; CCRF.CEM; CCRF CEM; CCRF; CEM; CEM-CCRF; CEM-CCRF (CAMR); CCRF/CEM/0; CEM/0; CEM-0; CCRF-CEM/S; GM03671; GM03671C 19.0 nM IC50 C7953 Orphanet_99861
TKC206874 MCF7 33.0 nM IC50 C4194
TKC206874 HeLa HELA; Hela; He La; He-La; HeLa-CCL2; Henrietta Lacks cells; Helacyton gartleri 62.0 nM IC50 C27677
TKC206874 BJ 26.0 nM IC50

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC206874 P0DTD1 Replicase polyprotein 1ab rep 11 % Inhibition
TKC206874 Q01705 Neurogenic locus notch homolog protein 1 Notch1 2700 nM IC50
TKC206874 P05027 Sodium/potassium-transporting ATPase subunit beta-1 ATP1B1 25 % Inhibition

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11