Basic Information

Terpenoid ID TKC206660
Chirality TKC109561
Cell line 0
Protein target 18
DiseaseNCIT 0
ORDO 0
ICD 44

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC206660 HepG2 1259.0 nM Potency C3728 Orphanet_449
TKC206660 HEK293 447.0 nM Potency
TKC206660 SN12C SN-12C 964.0 nM GI50 C9385 Orphanet_217071
TKC206660 MDA-N MDAN 2018.0 nM GI50 C3802
TKC206660 NCI-H23 NCI.H23; NCI H23; H-23; H23; NCIH23 1875.0 nM GI50 C3512
TKC206660 UO-31 UO.31; UO31; U031 2371.0 nM GI50 C9385 Orphanet_217071
TKC206660 ACHN 687.0 nM GI50 C6975 Orphanet_319298
TKC206660 HL-60 HL 60; HL.60 HL60; Human Leukemia-60 2884.0 nM GI50 C9154 Orphanet_519
TKC206660 HOP-92 HOP 92; HOP.92; HOP92; Hop92; Hopkins-92 5420.0 nM GI50 C2926
TKC206660 SF-539 SF-539; SF-539 BT; SF.539; SF 539 1294.0 nM GI50 C3796 Orphanet_251576
TKC206660 DU-145 DU-145; Du-145; DU 145; DU_145; DU.145; Duke University 145 1489.0 nM GI50 C4863
TKC206660 Malme-3M MALME-3M; MALME 3M; Malme-3 M; MALME.3M; Malme3M; MALME3M; Malme-3 Monolayer 2163.0 nM GI50 C3224
TKC206660 SK-MEL-5 SK-Mel-5; SK MEL 5; SK.MEL.5; SK-MEL5; SKMel-5; SKMEL-5; SKMEL5; SKMel5; SKmel5; AA-Mel 1151.0 nM GI50 C3510
TKC206660 K562 K562; K.562; K 562; KO; GM05372; GM05372E 3972.0 nM GI50 C9110 Orphanet_521
TKC206660 OVCAR-3 Ovcar-3; OVCAR 3; OVCAR.3; NIH:OVCAR-3; NIH:Ovcar-3; NIH:OVCAR3; NIH-OVCAR-3; NIHOVCAR3; OVCAR3; Ovcar3 3119.0 nM GI50 C105555
TKC206660 A498 A498 4498.0 nM GI50 C9385 Orphanet_217071
TKC206660 HOP-62 HOP 62; Hop 62; HOP.62; HOP62; Hop62; Hopkins-62 1603.0 nM GI50 C3512
TKC206660 MOLT-4 Molt-4; MOLT 4; Molt 4; MOLT.4; MOLT4; Molt4; GM02219; GM02219C; GM2219C; GM02219D 359.0 nM GI50 C9142 Orphanet_99861
TKC206660 NCI/ADR-RES NCI/ADR-RES; NCI.ADR.RES; NCIADR.RES; NCI/ADRRES; NCIADRRES; ADR-RES; MCF-7/ADR; MCF-7/ADR-RES; MCF-7/AdrR; MCF-7/Adr; MCF-7/adr; MCF-7ADR; MCF7-ADR; MCF7ADR; OVCAR-8/ADR; OVCAR8/ADR 2070.0 nM GI50 C105555
TKC206660 U-251 U-251 MG; U-251-MG; U-251_MG; U251-MG; U251MG; U-251; U251; U251n; U251N; 251 MG; 251MG; 251 MG(6) 6000.0 nM IC50 C60781 Orphanet_94
TKC206660 OVCAR-8 OVCAR 8; NIH:OVCAR-8; OVCAR8; Ovcar8; OVCAR.8; OVCA8 3076.0 nM GI50 C105555
TKC206660 OVCAR-5 OVCAR 5; NIH:OVCAR-5; OVCAR.5; OVCAR5; Ovcar5; OVCA5 4246.0 nM GI50 C105555
TKC206660 SNB-19 SNB.19; SNB19; Surgical Neurology Branch-19 4955.0 nM GI50 C60781 Orphanet_94
TKC206660 MDA-MB-231 MDA_MB_231; MDA-MB 231; MDA.MB.231; MDA MB 231; MDA MB231; MDA Mb231; MDA-MB231; MDAMB-231; MDAMB231; MDA-231; MDA-231P; MDA231; MDA231-BRE; MB231; MD Anderson-Metastatic Breast-231 8892.0 nM GI50 C5214
TKC206660 SR SR-786; SR786 100000.0 nM GI50 C37193 Orphanet_300895
TKC206660 SW-620 SW-620; SW 620; SW.620 3508.0 nM GI50 C4349
TKC206660 TK-10 TK.10; TK 10; TK10 3999.0 nM GI50 C4033 Orphanet_319276
TKC206660 NCI-H522 NCI.H522; H522; H-522; NCI-522; NCI522; NCIH522 719.0 nM GI50 C3512
TKC206660 M14 M14-MEL; UCLA-SO-M14; UCLA SO M14; UCLA-SO-14; UCLASO-M14; Melanoma 14; M-14 3451.0 nM GI50 C3802
TKC206660 KM12 KM-12; KM.12 5808.0 nM GI50 C4910
TKC206660 NCI-H322M NCI.H322M; H322M; H-322M; H-322m 3214.0 nM GI50 C2923
TKC206660 RPMI-8226 RPMI 8226; RPMI.8226; RPMI8226; RPMI no. 8226; RPMI no 8226; RPMI #8226; 8226; RPMI 8226/S; RPMI-8226S; RPMI8226/S; 8226/S; Roswell Park Memorial Institute 8226; GM02132; GM2132; GM 2132; GM02132C; Simpson 4207.0 nM GI50 C3242 Orphanet_29073
TKC206660 OVCAR-4 OVCAR 4; NIH:OVCAR-4; NIH:OVCAR4; OVCAR.4; OVCAR4; Ovcar4 2080.0 nM GI50 C105555
TKC206660 BT-549 BT 549; BT.549; BT549 1879.0 nM GI50 C4194
TKC206660 LOX IMVI LOX/IMVI; LOX IMVI; LOXIM-VI; LOXIMVI; LOX 2588.0 nM GI50 C3802
TKC206660 SK-MEL-2 SK-Mel-2; SK-Mel 2; SK-mel-2; SK-MEL2; SK.MEL.2; SK Mel 2; SK MEL 2; SKMEL-2; SKMEL2; SKmel2; SK-ML2; SKml2 3327.0 nM GI50 C3224
TKC206660 A549 627.0 nM GI50 C3512
TKC206660 HCC 2998 HCC-2998; HCC.2998; HCC 2998; Hamon Cancer Center 2998 3055.0 nM GI50 C4349
TKC206660 SNB-75 SNB.75; SNB75; Surgical Neurology Branch-75 3846.0 nM GI50 C3058 Orphanet_360
TKC206660 HCT-15 HCT-15; HCT.15; HCT15 1858.0 nM GI50 C4349
TKC206660 SF-268 SF-268; SF.268; SF 268 1746.0 nM GI50 C60781 Orphanet_94
TKC206660 HCT-116 HCT-116; HCT.116; HCT_116; HCT116; HCT116wt; CoCL2 1726.0 nM GI50 C4910
TKC206660 EKVX 2377.0 nM GI50 C3512
TKC206660 PC-3 PC3; PC.3 300.0 nM IC50 C4863
TKC206660 SK-OV-3 SKOV-3; SK-OV3; SK.OV.3; SKOV3; Skov3; SKO3 3214.0 nM GI50 C7978
TKC206660 T47D 3767.0 nM GI50 C4194
TKC206660 NCI-H460 NCI.H460; H460; H-460; NCIH460; NCI-HUT-460; NCI-460 673.0 nM GI50 C4450
TKC206660 UACC-62 UACC 62; UACC.62; UACC62; University of Arizona Cell Culture-62 3548.0 nM GI50 C3224
TKC206660 CAKI-1 CAL 1; Centre Antoine Lacassagne-1 1807.0 nM GI50 C3224
TKC206660 MDA-MB-435 MDA-MB435; MDAMB435; MDA.MB.435; MDA-435; MDA 435; MDA435; MD Anderson-Metastatic Breast-435 3034.0 nM GI50 C3802
TKC206660 SF-295 SF-295; SF.295; SF 295 2729.0 nM GI50 C3058 Orphanet_360
TKC206660 Hs-578T HS 578T; Hs-578T; HS-578T; Hs_578t; Hs-578-T; HS-578-T; Hs 578.T; HS578T; Hs578T; Hs578t; HS0578T; 578T; HS578; Hs578; Homo sapiens No. 578, tumor cells 4207.0 nM GI50 C4194
TKC206660 IGROV-1 Igrov-1; IGROV 1; IGR-OV1; IGROV1; Igrov1; IGR.OV1; IGROV; OV1/P; OV1/p; OV1-P 3258.0 nM GI50 C7979 Orphanet_454723
TKC206660 786-0 786-o; 786O; 786-0; 786.O; 786-O RCC; RCC 786-O; RCC_7860; RCC 7860; 7860; 786-0WT 1950.0 nM GI50 C9385 Orphanet_217071
TKC206660 UACC-257 UACC 257; UACC.257; UACC257; University of Arizona Cell Culture-257 4027.0 nM GI50 C3224
TKC206660 CCRF-CEM CCRF/CEM; CCRFCEM; CCRF.CEM; CCRF CEM; CCRF; CEM; CEM-CCRF; CEM-CCRF (CAMR); CCRF/CEM/0; CEM/0; CEM-0; CCRF-CEM/S; GM03671; GM03671C 760.0 nM GI50 C7953 Orphanet_99861
TKC206660 NCI-H226 NCI.H226; NCI H226; H226; H-226; HUT-226; HUT 226; NCIH226 11220.0 nM GI50 C45662 Orphanet_50251
TKC206660 HT-29 HT 29; HT29 3444.0 nM GI50 C4349
TKC206660 SK-MEL-28 SK-Mel-28; SK.MEL.28; SK-MEL 28; SK MEL-28; SK MEL 28; SK Mel 28; SKMel-28; SKMEL-28; SK-MEL28; SK-Mel28; SK Mel28; SKMEL28; SKMel28; SKmel28; SKML-28; SK28; AU-Mel; P-36; P36 7499.0 nM GI50 C3510
TKC206660 RXF 393 RXF393L; RXF-393 L; RXF-393; RXF 393; RXF.393; RXF393; RXF 393NL 736.0 nM GI50 C9385 Orphanet_217071
TKC206660 COLO 205 Colo 205; CoLo 205; COLO-205; Colo-205; COLO.205; Colo205; COLO205; Co 205; Colorado 205 3177.0 nM GI50 C4349
TKC206660 HeLa HELA; Hela; He La; He-La; HeLa-CCL2; Henrietta Lacks cells; Helacyton gartleri 3000.0 nM IC50 C27677
TKC206660 MCF7 6000.0 nM IC50 C4194
TKC206660 Calu-1 CaLu-1; CALU-1; Calu.1; CALU 1; Calu 1; CALU1; Calu1 8000.0 nM IC50 C3493
TKC206660 WI-38 VA13 WI 38 VA13 subline 2RA; WI 38 VA-13 subline 2RA; WI 38VA13 subline 2RA; WI-38 VA13 sub 2 RA; WI38-VA13 subline 2RA; WI38 VA13/2RA; WI38VA13/2RA; VA13 2RA; WI-38 VA13; WI 38 VA 13; WI38-VA13; WI38/VA13; WI38VA13; VA-13; VA13; AG07217; AG7217 1900000.0 nM IC50
TKC206660 HepG2 708.0 nM Potency C3728 Orphanet_449
TKC206660 A549 1680.0 nM IC50 C3512
TKC206660 MDA-MB-231 MDA_MB_231; MDA-MB 231; MDA.MB.231; MDA MB 231; MDA MB231; MDA Mb231; MDA-MB231; MDAMB-231; MDAMB231; MDA-231; MDA-231P; MDA231; MDA231-BRE; MB231; MD Anderson-Metastatic Breast-231 2.0 ug.mL-1 IC50 C5214
TKC206660 MCF7 2.0 ug.mL-1 IC50 C4194
TKC206660 TK-10 TK.10; TK 10; TK10 77.0 nM IC50 C4033 Orphanet_319276
TKC206660 UACC-62 UACC 62; UACC.62; UACC62; University of Arizona Cell Culture-62 349.0 nM IC50 C3224
TKC206660 HT-1080 Ht-1080; HT 1080; HT1080; HT 1080.T 1500.0 nM IC50 C3043 Orphanet_2030
TKC206660 KB KB (HeLa derivative); HeLa-KB; Strain KB 9610.0 nM IC50 C27677
TKC206660 NCI-H187 H187; H-187; NCIH187 9770.0 nM IC50 C4917 Orphanet_70573
TKC206660 MDA-N MDAN 168.0 nM GI50 C3802
TKC206660 SN12C SN-12C 35.0 nM GI50 C9385 Orphanet_217071
TKC206660 ACHN 12.0 nM GI50 C6975 Orphanet_319298
TKC206660 NCI-H23 NCI.H23; NCI H23; H-23; H23; NCIH23 34.0 nM GI50 C3512
TKC206660 UO-31 UO.31; UO31; U031 117.0 nM GI50 C9385 Orphanet_217071
TKC206660 HL-60 HL 60; HL.60 HL60; Human Leukemia-60 52.0 nM GI50 C9154 Orphanet_519
TKC206660 HOP-92 HOP 92; HOP.92; HOP92; Hop92; Hopkins-92 188.0 nM GI50 C2926
TKC206660 SF-539 SF-539; SF-539 BT; SF.539; SF 539 36.0 nM GI50 C3796 Orphanet_251576
TKC206660 DU-145 DU-145; Du-145; DU 145; DU_145; DU.145; Duke University 145 40.0 nM GI50 C4863
TKC206660 SK-MEL-5 SK-Mel-5; SK MEL 5; SK.MEL.5; SK-MEL5; SKMel-5; SKMEL-5; SKMEL5; SKMel5; SKmel5; AA-Mel 45.0 nM GI50 C3510
TKC206660 Malme-3M MALME-3M; MALME 3M; Malme-3 M; MALME.3M; Malme3M; MALME3M; Malme-3 Monolayer 62.0 nM GI50 C3224
TKC206660 A498 A498 125.0 nM GI50 C9385 Orphanet_217071
TKC206660 K562 K562; K.562; K 562; KO; GM05372; GM05372E 54.0 nM GI50 C9110 Orphanet_521
TKC206660 MOLT-4 Molt-4; MOLT 4; Molt 4; MOLT.4; MOLT4; Molt4; GM02219; GM02219C; GM2219C; GM02219D 10.0 nM GI50 C9142 Orphanet_99861
TKC206660 OVCAR-3 Ovcar-3; OVCAR 3; OVCAR.3; NIH:OVCAR-3; NIH:Ovcar-3; NIH:OVCAR3; NIH-OVCAR-3; NIHOVCAR3; OVCAR3; Ovcar3 37.0 nM GI50 C105555
TKC206660 NCI/ADR-RES NCI/ADR-RES; NCI.ADR.RES; NCIADR.RES; NCI/ADRRES; NCIADRRES; ADR-RES; MCF-7/ADR; MCF-7/ADR-RES; MCF-7/AdrR; MCF-7/Adr; MCF-7/adr; MCF-7ADR; MCF7-ADR; MCF7ADR; OVCAR-8/ADR; OVCAR8/ADR 115.0 nM GI50 C105555
TKC206660 HOP-62 HOP 62; Hop 62; HOP.62; HOP62; Hop62; Hopkins-62 40.0 nM GI50 C3512
TKC206660 U-251 U-251 MG; U-251-MG; U-251_MG; U251-MG; U251MG; U-251; U251; U251n; U251N; 251 MG; 251MG; 251 MG(6) 199.0 nM GI50 C60781 Orphanet_94
TKC206660 OVCAR-8 OVCAR 8; NIH:OVCAR-8; OVCAR8; Ovcar8; OVCAR.8; OVCA8 147.0 nM GI50 C105555
TKC206660 OVCAR-5 OVCAR 5; NIH:OVCAR-5; OVCAR.5; OVCAR5; Ovcar5; OVCA5 590.0 nM GI50 C105555
TKC206660 SNB-19 SNB.19; SNB19; Surgical Neurology Branch-19 851.0 nM GI50 C60781 Orphanet_94
TKC206660 SR SR-786; SR786 53.0 nM GI50 C37193 Orphanet_300895
TKC206660 SW-620 SW-620; SW 620; SW.620 118.0 nM GI50 C4349
TKC206660 NCI-H522 NCI.H522; H522; H-522; NCI-522; NCI522; NCIH522 10.0 nM GI50 C3512
TKC206660 KM12 KM-12; KM.12 713.0 nM GI50 C4910
TKC206660 M14 M14-MEL; UCLA-SO-M14; UCLA SO M14; UCLA-SO-14; UCLASO-M14; Melanoma 14; M-14 226.0 nM GI50 C3802
TKC206660 NCI-H322M NCI.H322M; H322M; H-322M; H-322m 169.0 nM GI50 C2923
TKC206660 RPMI-8226 RPMI 8226; RPMI.8226; RPMI8226; RPMI no. 8226; RPMI no 8226; RPMI #8226; 8226; RPMI 8226/S; RPMI-8226S; RPMI8226/S; 8226/S; Roswell Park Memorial Institute 8226; GM02132; GM2132; GM 2132; GM02132C; Simpson 76.0 nM GI50 C3242 Orphanet_29073
TKC206660 OVCAR-4 OVCAR 4; NIH:OVCAR-4; NIH:OVCAR4; OVCAR.4; OVCAR4; Ovcar4 66.0 nM GI50 C105555
TKC206660 LOX IMVI LOX/IMVI; LOX IMVI; LOXIM-VI; LOXIMVI; LOX 55.0 nM GI50 C3802
TKC206660 BT-549 BT 549; BT.549; BT549 37.0 nM GI50 C4194
TKC206660 SK-MEL-2 SK-Mel-2; SK-Mel 2; SK-mel-2; SK-MEL2; SK.MEL.2; SK Mel 2; SK MEL 2; SKMEL-2; SKMEL2; SKmel2; SK-ML2; SKml2 321.0 nM GI50 C3224
TKC206660 HCC 2998 HCC-2998; HCC.2998; HCC 2998; Hamon Cancer Center 2998 235.0 nM GI50 C4349
TKC206660 SNB-75 SNB.75; SNB75; Surgical Neurology Branch-75 299.0 nM GI50 C3058 Orphanet_360
TKC206660 HCT-116 HCT-116; HCT.116; HCT_116; HCT116; HCT116wt; CoCL2 25.0 nM GI50 C4910
TKC206660 HCT-15 HCT-15; HCT.15; HCT15 101.0 nM GI50 C4349
TKC206660 SF-268 SF-268; SF.268; SF 268 37.0 nM GI50 C60781 Orphanet_94
TKC206660 EKVX 87.0 nM GI50 C3512
TKC206660 PC-3 PC3; PC.3 2410.0 nM IC50 C4863
TKC206660 SK-OV-3 SKOV-3; SK-OV3; SK.OV.3; SKOV3; Skov3; SKO3 111.0 nM GI50 C7978
TKC206660 NCI-H460 NCI.H460; H460; H-460; NCIH460; NCI-HUT-460; NCI-460 920.0 nM IC50 C4450
TKC206660 T47D 2530.0 nM IC50 C4194
TKC206660 MDA-MB-435 MDA-MB435; MDAMB435; MDA.MB.435; MDA-435; MDA 435; MDA435; MD Anderson-Metastatic Breast-435 217.0 nM GI50 C3802
TKC206660 CAKI-1 CAL 1; Centre Antoine Lacassagne-1 36.0 nM GI50 C3224
TKC206660 IGROV-1 Igrov-1; IGROV 1; IGR-OV1; IGROV1; Igrov1; IGR.OV1; IGROV; OV1/P; OV1/p; OV1-P 67.0 nM GI50 C7979 Orphanet_454723
TKC206660 SF-295 SF-295; SF.295; SF 295 47.0 nM GI50 C3058 Orphanet_360
TKC206660 Hs-578T HS 578T; Hs-578T; HS-578T; Hs_578t; Hs-578-T; HS-578-T; Hs 578.T; HS578T; Hs578T; Hs578t; HS0578T; 578T; HS578; Hs578; Homo sapiens No. 578, tumor cells 92300.0 nM IC50 C4194
TKC206660 786-0 786-o; 786O; 786-0; 786.O; 786-O RCC; RCC 786-O; RCC_7860; RCC 7860; 7860; 786-0WT 45.0 nM GI50 C9385 Orphanet_217071
TKC206660 UACC-257 UACC 257; UACC.257; UACC257; University of Arizona Cell Culture-257 303.0 nM GI50 C3224
TKC206660 CCRF-CEM CCRF/CEM; CCRFCEM; CCRF.CEM; CCRF CEM; CCRF; CEM; CEM-CCRF; CEM-CCRF (CAMR); CCRF/CEM/0; CEM/0; CEM-0; CCRF-CEM/S; GM03671; GM03671C 30.0 nM GI50 C7953 Orphanet_99861
TKC206660 NCI-H226 NCI.H226; NCI H226; H226; H-226; HUT-226; HUT 226; NCIH226 1274.0 nM GI50 C45662 Orphanet_50251
TKC206660 HT-29 HT 29; HT29 209.0 nM GI50 C4349
TKC206660 SK-MEL-28 SK-Mel-28; SK.MEL.28; SK-MEL 28; SK MEL-28; SK MEL 28; SK Mel 28; SKMel-28; SKMEL-28; SK-MEL28; SK-Mel28; SK Mel28; SKMEL28; SKMel28; SKmel28; SKML-28; SK28; AU-Mel; P-36; P36 569.0 nM GI50 C3510
TKC206660 COLO 205 Colo 205; CoLo 205; COLO-205; Colo-205; COLO.205; Colo205; COLO205; Co 205; Colorado 205 440.0 nM GI50 C4349
TKC206660 RXF 393 RXF393L; RXF-393 L; RXF-393; RXF 393; RXF.393; RXF393; RXF 393NL 14.0 nM GI50 C9385 Orphanet_217071
TKC206660 SK-BR-3 SK-Br-3; Sk-Br-3; SK BR 03; SKBR-3; SKBr-3; SK-BR3; SKBr3; SkBr3; SKBR3 4420.0 nM IC50 C5214
TKC206660 HCT-8 HCT-8; HCT8 2480.0 nM IC50 C4349
TKC206660 LNCaP LNCAP; LNCap; Ln-Cap; Lymph Node Carcinoma of the prostate 3700.0 nM IC50 C4863
TKC206660 MRC5 MRC5; MRC 5; MRCV; MRC-V; Medical Research Council cell strain-5 1160.0 nM IC50

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC206660 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 TDP1 16360 nM Potency
TKC206660 O75874 Isocitrate dehydrogenase [NADP] cytoplasmic IDH1 1458 nM Potency
TKC206660 P43220 Glucagon-like peptide 1 receptor GLP1R 1122 nM Potency
TKC206660 P84022 Mothers against decapentaplegic homolog 3 SMAD3 1300 nM Potency
TKC206660 Q06710 Paired box protein Pax-8 PAX8 2090 nM AC50
TKC206660 Q16236 Nuclear factor erythroid 2-related factor 2 NFE2L2 259 nM Potency
TKC206660 Q99700 Ataxin-2 ATXN2 336 nM Potency
TKC206660 O75496 Geminin GMNN 651 nM Potency
TKC206660 O89049 Thioredoxin reductase 1, cytoplasmic Txnrd1 89125 nM Potency
TKC206660 P0DTD1 Replicase polyprotein 1ab rep 3 % Inhibition
TKC206660 P83916 Chromobox protein homolog 1 CBX1 70795 nM Potency
TKC206660 Q96KQ7 Histone-lysine N-methyltransferase EHMT2 EHMT2 4467 nM Potency
TKC206660 Q96QE3 ATPase family AAA domain-containing protein 5 ATAD5 517 nM Potency
TKC206660 P05023 Sodium/potassium-transporting ATPase subunit alpha-1 ATP1A1 8 nM IC50
TKC206660 O15118 NPC intracellular cholesterol transporter 1 NPC1 1259 nM Potency
TKC206660 P51151 Ras-related protein Rab-9A RAB9A 1259 nM Potency
TKC206660 P16473 Thyrotropin receptor TSHR 478 nM Potency
TKC206660 P54707 Potassium-transporting ATPase alpha chain 2 ATP12A 80 nM IC50
TKC206660 P22310 UDP-glucuronosyltransferase 1A4 UGT1A4 0 pm/min/mg Activity
TKC206660 O43521 Bcl-2-like protein 11 BCL2L11 >350000 nM EC50
TKC206660 P50997 Sodium/potassium-transporting ATPase subunit alpha-1 ATP1A1 500 nM IC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
O75874 IDHC_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
O75874 IDHC_HUMAN Liver cancer [ICD-11: 2C12]
O75874 IDHC_HUMAN Malignant haematopoietic neoplasm [ICD-11: 2B33]
O75874 IDHC_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
O75874 IDHC_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
O75874 IDHC_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P43220 GLP1R_HUMAN Cardiovascular disease [ICD-11: BA00-BE2Z]
P43220 GLP1R_HUMAN Obesity [ICD-11: 5B80-5B81]
P43220 GLP1R_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
P43220 GLP1R_HUMAN Type-1/2 diabete [ICD-11: 5A10-5A11]
P43220 GLP1R_HUMAN Acute diabete complication [ICD-11: 5A2Y]
P43220 GLP1R_HUMAN Diabetes mellitus [ICD-11: 5A10]
P43220 GLP1R_HUMAN Dyspepsia [ICD-11: MD92]
P43220 GLP1R_HUMAN Irritable bowel syndrome [ICD-11: DD91]
P43220 GLP1R_HUMAN Intracranial injury [ICD-11: NA07]
P43220 GLP1R_HUMAN Non-alcoholic fatty liver disease [ICD-11: DB92]
P84022 SMAD3_HUMAN Herpes simplex infection [ICD-11: 1F00]
P84022 SMAD3_HUMAN Kidney fibrosis [ICD-11: GC01]
Q16236 NF2L2_HUMAN Ataxic disorder [ICD-11: 8A03]
Q16236 NF2L2_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
Q16236 NF2L2_HUMAN Glaucoma [ICD-11: 9C61]
Q16236 NF2L2_HUMAN Lung cancer [ICD-11: 2C25]
Q16236 NF2L2_HUMAN Macular degeneration [ICD-11: 9B75]
Q16236 NF2L2_HUMAN Melanoma [ICD-11: 2C30]
Q16236 NF2L2_HUMAN Mental/behavioural/neurodevelopmental disorder [ICD-11: 6E20-6E8Z]
Q16236 NF2L2_HUMAN Pulmonary hypertension [ICD-11: BB01]
Q16236 NF2L2_HUMAN Subarachnoid haemorrhage [ICD-11: 8B01]
Q16236 NF2L2_HUMAN Urinary system clinical sympton [ICD-11: MF8Y]
Q16236 NF2L2_HUMAN Non-alcoholic fatty liver disease [ICD-11: DB92]
Q16236 NF2L2_HUMAN Alpha-1-antitrypsin deficiency [ICD-11: 5C5A]
Q16236 NF2L2_HUMAN Motor neuron disease [ICD-11: 8B60]
Q16236 NF2L2_HUMAN Multiple sclerosis [ICD-11: 8A40]
Q96KQ7 EHMT2_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
Q96KQ7 EHMT2_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
Q96KQ7 EHMT2_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P05023 AT1A1_HUMAN Cardiac arrhythmia [ICD-11: BC9Z]
P05023 AT1A1_HUMAN Chronic obstructive pulmonary disease [ICD-11: CA22]
P05023 AT1A1_HUMAN Corneal disease [ICD-11: 9A76-9A78]
P05023 AT1A1_HUMAN Heart failure [ICD-11: BD10-BD1Z]
P05023 AT1A1_HUMAN Hyperhidrosis [ICD-11: EE00]
P05023 AT1A1_HUMAN Malaria [ICD-11: 1F40-1F45]
P05023 AT1A1_HUMAN Supraventricular tachyarrhythmia [ICD-11: BC81]
P05023 AT1A1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P51151 RAB9A_HUMAN Fungal infection [ICD-11: 1F29-1F2F]
P16473 TSHR_HUMAN Hypo-thyroidism [ICD-11: 5A00]
P16473 TSHR_HUMAN Thyroid cancer [ICD-11: 2D10]