Basic Information

Terpenoid ID TKC206656
Chirality TKC109503
Cell line 15
Protein target 2
DiseaseNCIT 14
ORDO 5
ICD 0

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC206656 HepG2 35.0 nM EC50 C3728 Orphanet_449
TKC206656 HeLa HELA; Hela; He La; He-La; HeLa-CCL2; Henrietta Lacks cells; Helacyton gartleri 28.0 nM IC50 C27677
TKC206656 BGC-823 BGC823 45.0 nM IC50 C27677
TKC206656 KB KB (HeLa derivative); HeLa-KB; Strain KB 1.0 ug.mL-1 IC50 C27677
TKC206656 Bel-7402 Bel-7402; BEL 7402; Bel 7402; BEL7402; Bel7402 7.0 nM IC50 C27677
TKC206656 A549 600.0 nM IC50 C3512
TKC206656 SK-OV-3 SKOV-3; SK-OV3; SK.OV.3; SKOV3; Skov3; SKO3 10.0 nM EC50 C7978
TKC206656 HCT-116 HCT-116; HCT.116; HCT_116; HCT116; HCT116wt; CoCL2 11.0 nM EC50 C4910
TKC206656 MES-SA MESSA 28.0 nM EC50 C6339 Orphanet_213620
TKC206656 MES-SA/Dx5 MES-SA/Dx-5; MES-SA-Dx5; MES-SA Dx5; MESSA/Dx5; MESSA-DX5; MESSA Dx5; MESSADX5; Dx5 18.0 nM EC50 C6339 Orphanet_213620
TKC206656 786-0 786-o; 786O; 786-0; 786.O; 786-O RCC; RCC 786-O; RCC_7860; RCC 7860; 7860; 786-0WT 8.0 nM EC50 C9385 Orphanet_217071
TKC206656 MCF7 42.0 nM EC50 C4194
TKC206656 BXPC-3 BxPc-3; BXPC-3; Bx-PC3; BXPC3; BxPC3; BxPc3; Biopsy xenograft of Pancreatic Carcinoma line-3 11.0 nM EC50 C9120
TKC206656 U-87 MG 14.0 nM EC50 C3058 Orphanet_360
TKC206656 NCI-H1975 H1975; H-1975; NCIH1975 13.0 nM EC50 C3512
TKC206656 HUVEC HUV-EC-C; HUVEC 12.0 nM EC50

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC206656 O42275 Acetylcholinesterase ache 17 % Inhibition
TKC206656 P81908 Cholinesterase BCHE 0 % Inhibition

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11