Basic Information

Terpenoid ID TKC206133
Chirality TKC055972
Cell line 0
Protein target 3
DiseaseNCIT 0
ORDO 0
ICD 7

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC206133 MDA-MB-231 MDA_MB_231; MDA-MB 231; MDA.MB.231; MDA MB 231; MDA MB231; MDA Mb231; MDA-MB231; MDAMB-231; MDAMB231; MDA-231; MDA-231P; MDA231; MDA231-BRE; MB231; MD Anderson-Metastatic Breast-231 84700.0 nM IC50 C5214
TKC206133 MCF7 75660.0 nM IC50 C4194
TKC206133 TERT-RPE1 hTERT RPE1; hTERT-RPE-1; hTERT RPE-1; hTERT-RPE; TERT-RPE1; RPE-1; RPE1; RPE1-hTERT; RPE1-hTert; RPE-hTERT 63410.0 nM IC50
TKC206133 HCT-116 HCT-116; HCT.116; HCT_116; HCT116; HCT116wt; CoCL2 75080.0 nM IC50 C4910
TKC206133 HCT-8 HCT-8; HCT8 82220.0 nM IC50 C4349
TKC206133 CT26 CT-26; CT 26; Colon Tumor 26 70480.0 nM IC50 C120044
TKC206133 PC-3 PC3; PC.3 88040.0 nM IC50 C4863
TKC206133 DU-145 DU-145; Du-145; DU 145; DU_145; DU.145; Duke University 145 136400.0 nM IC50 C4863
TKC206133 4T1 4T1-A; 4T1.0; 4T1/WT 96220.0 nM IC50 C21678

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC206133 P18031 Tyrosine-protein phosphatase non-receptor type 1 PTPN1 81 % Inhibition
TKC206133 Q9NPD5 Solute carrier organic anion transporter family member 1B3 SLCO1B3 59 % Inhibition
TKC206133 Q9Y6L6 Solute carrier organic anion transporter family member 1B1 SLCO1B1 47 % Inhibition

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P18031 PTN1_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
P18031 PTN1_HUMAN Acute diabete complication [ICD-11: 5A2Y]
P18031 PTN1_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
P18031 PTN1_HUMAN Obesity [ICD-11: 5B80-5B81]
P18031 PTN1_HUMAN Ophthalmic devices/implants/grafts injury [ICD-11: PK97]
P18031 PTN1_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
P18031 PTN1_HUMAN Metabolic disorder [ICD-11: 5C50-5D2Z]
P18031 PTN1_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]