Basic Information

Terpenoid ID TKC171641
Cell line 6
Protein target 1
DiseaseNCIT 7
ORDO 3
ICD 8

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC171641 FaDu FaDU; FADU 57.0 nM IC50 C4043 Orphanet_494547
TKC171641 HCT-116 HCT-116; HCT.116; HCT_116; HCT116; HCT116wt; CoCL2 62.0 nM IC50 C4910
TKC171641 SN12C SN-12C 92.0 nM IC50 C9385 Orphanet_217071
TKC171641 MKN-45 MKN-45; MKN 45 130.0 nM IC50 C4004
TKC171641 A549 320.0 nM LC50 C3512
TKC171641 K562 K562; K.562; K 562; KO; GM05372; GM05372E 260.0 nM LC50 C9110 Orphanet_521

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC171641 P05023 Sodium/potassium-transporting ATPase subunit alpha-1 ATP1A1 >100000 nM IC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P05023 AT1A1_HUMAN Cardiac arrhythmia [ICD-11: BC9Z]
P05023 AT1A1_HUMAN Chronic obstructive pulmonary disease [ICD-11: CA22]
P05023 AT1A1_HUMAN Corneal disease [ICD-11: 9A76-9A78]
P05023 AT1A1_HUMAN Heart failure [ICD-11: BD10-BD1Z]
P05023 AT1A1_HUMAN Hyperhidrosis [ICD-11: EE00]
P05023 AT1A1_HUMAN Malaria [ICD-11: 1F40-1F45]
P05023 AT1A1_HUMAN Supraventricular tachyarrhythmia [ICD-11: BC81]
P05023 AT1A1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]