Basic Information

Terpenoid ID TKC152493
Chirality TKC152480
Cell line 0
Protein target 1
DiseaseNCIT 0
ORDO 0
ICD 0

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC152493 BXPC-3 BxPc-3; BXPC-3; Bx-PC3; BXPC3; BxPC3; BxPc3; Biopsy xenograft of Pancreatic Carcinoma line-3 1.0 ug.mL-1 GI50 C9120
TKC152493 MCF7 20.0 ug.mL-1 IC50 C4194
TKC152493 SF-268 SF-268; SF.268; SF 268 2.0 ug.mL-1 GI50 C60781 Orphanet_94
TKC152493 NCI-H460 NCI.H460; H460; H-460; NCIH460; NCI-HUT-460; NCI-460 50000.0 nM IC50 C4450
TKC152493 KM-20L2 KM-20L2; KM 20L2; KM 2012 1.0 ug.mL-1 GI50 C4349
TKC152493 DU-145 DU-145; Du-145; DU 145; DU_145; DU.145; Duke University 145 9.0 ug.mL-1 GI50 C4863
TKC152493 THP-1 THP1; THP 1; THPI; THP-1(ATCC); THP-1-O; O-THP-1; Tohoku Hospital Pediatrics-1 6960.0 nM IC50 C9163 Orphanet_514
TKC152493 HCT-116 HCT-116; HCT.116; HCT_116; HCT116; HCT116wt; CoCL2 10800.0 nM IC50 C4910
TKC152493 HBL-100 HBL 100; HBL100 10800.0 nM IC50

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC152493 Q9NPD5 Solute carrier organic anion transporter family member 1B3 SLCO1B3 85 % Inhibition
TKC152493 Q9Y6L6 Solute carrier organic anion transporter family member 1B1 SLCO1B1 86 % Inhibition
TKC152493 P0DTD1 Replicase polyprotein 1ab rep -16 % Inhibition
TKC152493 P22309 UDP-glucuronosyltransferase 1A1 UGT1A1 0 pm/min/mg Activity
TKC152493 P22310 UDP-glucuronosyltransferase 1A4 UGT1A4 13000 nM Km
TKC152493 P35503 UDP-glucuronosyltransferase 1A3 UGT1A3 0 pm/min/mg Activity
TKC152493 Q9HAW9 UDP-glucuronosyltransferase 1A8 UGT1A8 0 pm/min/mg Activity

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P22309 UD11_HUMAN Inborn porphyrin/heme metabolism error [ICD-11: 5C58]