Basic Information

Terpenoid ID TKC151825
Cell line 6
Protein target 1
DiseaseNCIT 6
ORDO 2
ICD 6

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC151825 WI-38 VA13 WI 38 VA13 subline 2RA; WI 38 VA-13 subline 2RA; WI 38VA13 subline 2RA; WI-38 VA13 sub 2 RA; WI38-VA13 subline 2RA; WI38 VA13/2RA; WI38VA13/2RA; VA13 2RA; WI-38 VA13; WI 38 VA 13; WI38-VA13; WI38/VA13; WI38VA13; VA-13; VA13; AG07217; AG7217 61100.0 nM IC50
TKC151825 HepG2 41700.0 nM IC50 C3728 Orphanet_449
TKC151825 MCF7 23988.0 nM GI50 C4194
TKC151825 MDA-MB-231 MDA_MB_231; MDA-MB 231; MDA.MB.231; MDA MB 231; MDA MB231; MDA Mb231; MDA-MB231; MDAMB-231; MDAMB231; MDA-231; MDA-231P; MDA231; MDA231-BRE; MB231; MD Anderson-Metastatic Breast-231 18000.0 nM GI50 C5214
TKC151825 U-251 U-251 MG; U-251-MG; U-251_MG; U251-MG; U251MG; U-251; U251; U251n; U251N; 251 MG; 251MG; 251 MG(6) 36000.0 nM GI50 C60781 Orphanet_94
TKC151825 SF-268 SF-268; SF.268; SF 268 74000.0 nM GI50 C60781 Orphanet_94
TKC151825 SF-295 SF-295; SF.295; SF 295 21000.0 nM GI50 C3058 Orphanet_360
TKC151825 SF-539 SF-539; SF-539 BT; SF.539; SF 539 44668.0 nM GI50 C3796 Orphanet_251576
TKC151825 SNB-75 SNB.75; SNB75; Surgical Neurology Branch-75 8913.0 nM GI50 C3058 Orphanet_360
TKC151825 SNB-78 SNB78; Surgical Neurology Branch-78 50000.0 nM GI50 C3058 Orphanet_360
TKC151825 HCC 2998 HCC-2998; HCC.2998; HCC 2998; Hamon Cancer Center 2998 27000.0 nM GI50 C4349
TKC151825 KM12 KM-12; KM.12 41687.0 nM GI50 C4910
TKC151825 HT-29 HT 29; HT29 27542.0 nM GI50 C4349
TKC151825 HCT-15 HCT-15; HCT.15; HCT15 32000.0 nM GI50 C4349
TKC151825 HCT-116 HCT-116; HCT.116; HCT_116; HCT116; HCT116wt; CoCL2 30000.0 nM GI50 C4910
TKC151825 NCI-H23 NCI.H23; NCI H23; H-23; H23; NCIH23 22909.0 nM GI50 C3512
TKC151825 NCI-H226 NCI.H226; NCI H226; H226; H-226; HUT-226; HUT 226; NCIH226 32000.0 nM GI50 C45662 Orphanet_50251
TKC151825 NCI-H522 NCI.H522; H522; H-522; NCI-522; NCI522; NCIH522 15000.0 nM GI50 C3512
TKC151825 NCI-H460 NCI.H460; H460; H-460; NCIH460; NCI-HUT-460; NCI-460 35481.0 nM GI50 C4450
TKC151825 A549 30000.0 nM GI50 C3512
TKC151825 DMS-273 DMS-273; DMS273; Darmouth Medical School 273 22000.0 nM GI50 C4917 Orphanet_70573
TKC151825 DMS-114 DMS-114; DMS114; Darmouth Medical School 114 10000.0 nM GI50 C4917 Orphanet_70573
TKC151825 LOX IMVI LOX/IMVI; LOX IMVI; LOXIM-VI; LOXIMVI; LOX 34674.0 nM GI50 C3802
TKC151825 OVCAR-3 Ovcar-3; OVCAR 3; OVCAR.3; NIH:OVCAR-3; NIH:Ovcar-3; NIH:OVCAR3; NIH-OVCAR-3; NIHOVCAR3; OVCAR3; Ovcar3 20417.0 nM GI50 C105555
TKC151825 OVCAR-4 OVCAR 4; NIH:OVCAR-4; NIH:OVCAR4; OVCAR.4; OVCAR4; Ovcar4 21000.0 nM GI50 C105555
TKC151825 OVCAR-5 OVCAR 5; NIH:OVCAR-5; OVCAR.5; OVCAR5; Ovcar5; OVCA5 47863.0 nM GI50 C105555
TKC151825 OVCAR-8 OVCAR 8; NIH:OVCAR-8; OVCAR8; Ovcar8; OVCAR.8; OVCA8 37000.0 nM GI50 C105555
TKC151825 SK-OV-3 SKOV-3; SK-OV3; SK.OV.3; SKOV3; Skov3; SKO3 68000.0 nM GI50 C7978
TKC151825 ACHN 28000.0 nM GI50 C6975 Orphanet_319298
TKC151825 St-4 33000.0 nM GI50 C4911
TKC151825 MKN-7 MKN-7; MKN 7 18000.0 nM GI50 C5473
TKC151825 MKN-28 MKN-28; MKN 28 30903.0 nM GI50 C5473
TKC151825 MKN-45 MKN-45; MKN 45 26915.0 nM GI50 C4004
TKC151825 MKN-74 MKN-74; MKN 74 30000.0 nM GI50 C5473
TKC151825 DU-145 DU-145; Du-145; DU 145; DU_145; DU.145; Duke University 145 32359.0 nM GI50 C4863
TKC151825 PC-3 PC3; PC.3 19953.0 nM GI50 C4863
TKC151825 P388 P-388 229086765.0 nM IC50 C21602
TKC151825 HT-1080 Ht-1080; HT 1080; HT1080; HT 1080.T 85.0 ug.mL-1 EC50 C3043 Orphanet_2030

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC151825 P08183 ATP-dependent translocase ABCB1 ABCB1 86 % Activity

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P08183 MDR1_HUMAN Lung cancer [ICD-11: 2C25]
P08183 MDR1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P08183 MDR1_HUMAN Bacterial infection [ICD-11: 1A00-1C4Z]
P08183 MDR1_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
P08183 MDR1_HUMAN Adrenal cancer [ICD-11: 2D11]
P08183 MDR1_HUMAN Ovarian cancer [ICD-11: 2C73]