Basic Information

Terpenoid ID TKC151390
Chirality TKC071409
Cell line 0
Protein target 4
DiseaseNCIT 0
ORDO 0
ICD 0

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC151390 MCF7 9800.0 nM CC50 C4194
TKC151390 KB KB (HeLa derivative); HeLa-KB; Strain KB 36180.0 nM CC50 C27677
TKC151390 PBMC 27431.0 nM IC50
TKC151390 CCRF-CEM CCRF/CEM; CCRFCEM; CCRF.CEM; CCRF CEM; CCRF; CEM; CEM-CCRF; CEM-CCRF (CAMR); CCRF/CEM/0; CEM/0; CEM-0; CCRF-CEM/S; GM03671; GM03671C 69.0 nM EC50 C7953 Orphanet_99861
TKC151390 ADR5000 cell line CCRF ADR5000; CCRF-ADR5000; CEM/ADR5000; CEM/ADR 5000; CEM-ADR5000; CEM ADR5000; ADR5000 100.0 nM EC50 C7953 Orphanet_99861
TKC151390 HEK293 2900.0 nM IC50
TKC151390 HepG2 6500.0 nM IC50 C3728 Orphanet_449
TKC151390 MRC5 MRC5; MRC 5; MRCV; MRC-V; Medical Research Council cell strain-5 6800.0 nM IC50
TKC151390 HeLa HELA; Hela; He La; He-La; HeLa-CCL2; Henrietta Lacks cells; Helacyton gartleri 3200.0 nM IC50 C27677
TKC151390 L6 L-6; L-6 myoblast 1500.0 nM IC50
TKC151390 SK-HEP1 SK-Hep-1; SK HEP-1; SK HEP 01; SK-Hep1; Sk-Hep1; SK Hep1; SKHEP-1; SKHEP1; SKHep1; SK_HEP1 10000.0 nM IC50 C7106
TKC151390 MCF-10A MCF 10A; MCF.10A; MCF10A; MCF10-A; MCF10a; MCF-10 Attached; Michigan Cancer Foundation-10A 21000.0 nM IC50
TKC151390 BT-474 Bt-474; BT474 7800.0 nM IC50 C4194
TKC151390 MDA-MB-231 MDA_MB_231; MDA-MB 231; MDA.MB.231; MDA MB 231; MDA MB231; MDA Mb231; MDA-MB231; MDAMB-231; MDAMB231; MDA-231; MDA-231P; MDA231; MDA231-BRE; MB231; MD Anderson-Metastatic Breast-231 10040.0 nM EC50 C5214
TKC151390 HL-60 HL 60; HL.60 HL60; Human Leukemia-60 2000.0 nM IC50 C9154 Orphanet_519
TKC151390 MCF7 38710.0 nM IC50 C4194
TKC151390 K562/Adr K562/adr; K-562adr; K562adr; K562/ADM 78.0 % Activity C9110 Orphanet_521
TKC151390 K562 K562; K.562; K 562; KO; GM05372; GM05372E 5999.0 nM IC50 C9110 Orphanet_521
TKC151390 HUVEC HUV-EC-C; HUVEC 1092.0 nM IC50
TKC151390 A549 15921.0 nM IC50 C3512
TKC151390 T47D 2220.0 nM EC50 C4194
TKC151390 MDA-MB-361 MDA-MB 361; MDA MB 361; MDA-MB361; MDAMB361; MDA-361; MDA361; MB361; MD Anderson-Metastatic Breast-361 2270.0 nM EC50 C5214
TKC151390 C-33-A C33A; C33a; C33-A; C-33-A; C-33A; C33 1830.0 nM EC50 C180839 Orphanet_213767
TKC151390 L02 L02; LO2; HL-7702; HL7702; Liver-02; Human Liver-7702 72170.0 nM IC50 C27677
TKC151390 KB KB (HeLa derivative); HeLa-KB; Strain KB 78500.0 nM IC50 C27677
TKC151390 Y79 Y79; GM01232; GM01232E 80.0 % Activity C7541 Orphanet_790
TKC151390 H22 Hepatoma-22; Hepatoma 22 49.0 % TGI C38756
TKC151390 HCT-116 HCT-116; HCT.116; HCT_116; HCT116; HCT116wt; CoCL2 890.0 nM IC50 C4910
TKC151390 WM 266-4 WM-266-4; WM 266-4; WM-2664; WM2664; WM 2664; WM266; WM-266-mel; WM266mel; WC00097 8460.0 nM IC50 C3224

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC151390 Q00653 Nuclear factor NF-kappa-B p100 subunit NFKB2 35 % Activity
TKC151390 O42275 Acetylcholinesterase ache -6 % Inhibition
TKC151390 P0DTD1 Replicase polyprotein 1ab rep 4 % Inhibition
TKC151390 P81908 Cholinesterase BCHE 5 % Inhibition
TKC151390 O15438 ATP-binding cassette sub-family C member 3 ABCC3 133000 nM IC50
TKC151390 O15439 ATP-binding cassette sub-family C member 4 ABCC4 133000 nM IC50
TKC151390 O95342 Bile salt export pump ABCB11 133000 nM IC50
TKC151390 Q92887 ATP-binding cassette sub-family C member 2 ABCC2 133000 nM IC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
Q00653 NFKB2_HUMAN Ulcerative colitis [ICD-11: DD71]