Basic Information

Terpenoid ID TKC150004
Chirality TKC013305
Cell line 0
Protein target 1
DiseaseNCIT 0
ORDO 0
ICD 7

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC150004 HeLa HELA; Hela; He La; He-La; HeLa-CCL2; Henrietta Lacks cells; Helacyton gartleri 46600.0 nM IC50 C27677
TKC150004 U-251 U-251 MG; U-251-MG; U-251_MG; U251-MG; U251MG; U-251; U251; U251n; U251N; 251 MG; 251MG; 251 MG(6) 27800.0 nM IC50 C60781 Orphanet_94
TKC150004 HCT-15 HCT-15; HCT.15; HCT15 22500.0 nM IC50 C4349
TKC150004 U-87 MG 8020.0 nM IC50 C3058 Orphanet_360
TKC150004 SW-620 SW-620; SW 620; SW.620 5850.0 nM IC50 C4349

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC150004 P18031 Tyrosine-protein phosphatase non-receptor type 1 PTPN1 32600 nM IC50
TKC150004 P17706 Tyrosine-protein phosphatase non-receptor type 2 PTPN2 <50 % Inhibition
TKC150004 P10586 Receptor-type tyrosine-protein phosphatase F PTPRF <50 % Inhibition
TKC150004 P29350 Tyrosine-protein phosphatase non-receptor type 6 PTPN6 <50 % Inhibition
TKC150004 Q06124 Tyrosine-protein phosphatase non-receptor type 11 PTPN11 <50 % Inhibition
TKC150004 P30305 M-phase inducer phosphatase 2 CDC25B <50 % Inhibition

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P18031 PTN1_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
P18031 PTN1_HUMAN Acute diabete complication [ICD-11: 5A2Y]
P18031 PTN1_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
P18031 PTN1_HUMAN Obesity [ICD-11: 5B80-5B81]
P18031 PTN1_HUMAN Ophthalmic devices/implants/grafts injury [ICD-11: PK97]
P18031 PTN1_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
P18031 PTN1_HUMAN Metabolic disorder [ICD-11: 5C50-5D2Z]
P18031 PTN1_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
P17706 PTN2_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
Q06124 PTN11_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P30305 MPIP2_HUMAN Lung cancer [ICD-11: 2C25]
P30305 MPIP2_HUMAN Nasopharyngeal cancer [ICD-11: 2B6B]
P30305 MPIP2_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]