Basic Information

Terpenoid ID TKC148168
Chirality TKC106952
Cell line 4
Protein target 3
DiseaseNCIT 4
ORDO 1
ICD 0

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC148168 A2780 A-2780; 2780; A2780S; A2780par 12.0 ug.mL-1 IC50 C7979 Orphanet_454723
TKC148168 RAW264.7 RAW264 38.0 % Inhibition C21604
TKC148168 MCF7 26730.0 nM IC50 C4194
TKC148168 HL-60 HL 60; HL.60 HL60; Human Leukemia-60 14600.0 nM GI50 C9154 Orphanet_519
TKC148168 SK-OV-3 SKOV-3; SK-OV3; SK.OV.3; SKOV3; Skov3; SKO3 14600.0 nM GI50 C7978
TKC148168 A549 11400.0 nM GI50 C3512
TKC148168 HT-29 HT 29; HT29 12500.0 nM GI50 C4349

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC148168 Q9NPD5 Solute carrier organic anion transporter family member 1B3 SLCO1B3 110 % Inhibition
TKC148168 Q9Y6L6 Solute carrier organic anion transporter family member 1B1 SLCO1B1 113 % Inhibition
TKC148168 P29477 Nitric oxide synthase, inducible Nos2 >50000 nM IC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11