Basic Information

Terpenoid ID TKC148105
Cell line 0
Protein target 1
DiseaseNCIT 0
ORDO 0
ICD 7

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC148105 SK-MEL SK-Mel-1; SK Mel 1; SK-Mel 1; SK-Mel1; SKMEL-1; SkMEL-1; SKMEL1; SK 1 103000.0 nM IC50 C3224
TKC148105 A549 55700.0 nM IC50 C3512
TKC148105 WI-38 VA13 WI 38 VA13 subline 2RA; WI 38 VA-13 subline 2RA; WI 38VA13 subline 2RA; WI-38 VA13 sub 2 RA; WI38-VA13 subline 2RA; WI38 VA13/2RA; WI38VA13/2RA; VA13 2RA; WI-38 VA13; WI 38 VA 13; WI38-VA13; WI38/VA13; WI38VA13; VA-13; VA13; AG07217; AG7217 121000.0 nM IC50
TKC148105 IMR-32 IMR 32; IMR32; Institute for Medical Research-32; GM03320; GM3320C; GM03320D; AG03320; AG3320 55.0 % GI C3270 Orphanet_635
TKC148105 HeLa HELA; Hela; He La; He-La; HeLa-CCL2; Henrietta Lacks cells; Helacyton gartleri 100000.0 nM IC50 C27677
TKC148105 SiHa Siha; SIHA 21.0 % GI C27676 Orphanet_213767
TKC148105 SW-620 SW-620; SW 620; SW.620 8.0 % GI C4349

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC148105 P18031 Tyrosine-protein phosphatase non-receptor type 1 PTPN1 4440 nM IC50
TKC148105 P00921 Carbonic anhydrase 2 CA2 >10000 nM Ki

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P18031 PTN1_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
P18031 PTN1_HUMAN Acute diabete complication [ICD-11: 5A2Y]
P18031 PTN1_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
P18031 PTN1_HUMAN Obesity [ICD-11: 5B80-5B81]
P18031 PTN1_HUMAN Ophthalmic devices/implants/grafts injury [ICD-11: PK97]
P18031 PTN1_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
P18031 PTN1_HUMAN Metabolic disorder [ICD-11: 5C50-5D2Z]
P18031 PTN1_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]