Basic Information

Terpenoid ID TKC146326
Cell line 0
Protein target 3
DiseaseNCIT 0
ORDO 0
ICD 2

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC146326 MCF7 37800.0 nM GI50 C4194
TKC146326 OVCAR-3 Ovcar-3; OVCAR 3; OVCAR.3; NIH:OVCAR-3; NIH:Ovcar-3; NIH:OVCAR3; NIH-OVCAR-3; NIHOVCAR3; OVCAR3; Ovcar3 37400.0 nM GI50 C105555
TKC146326 P388 P-388 6600.0 nM IC50 C21602
TKC146326 A549 13200.0 nM IC50 C3512
TKC146326 HT-29 HT 29; HT29 13200.0 nM IC50 C4349
TKC146326 CAPAN-1 CaPan-1; CAPAN-1; Capan 1; CAPAN 1; Capan1; CAPAN1 93000.0 nM IC50 C9120
TKC146326 Calu-6 CaLu-6; CALU-6; Calu.6; Calu 6; Calu6; CALU6; CaLu-06 44000.0 nM IC50 C3512
TKC146326 A-431 A431; A431/P 27000.0 nM IC50 C4819
TKC146326 HaCaT HaCAT; HACAT; Hacat 80000.0 nM IC50

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC146326 P0A749 UDP-N-acetylglucosamine 1-carboxyvinyltransferase murA 16700 nM IC50
TKC146326 P01103 Transcriptional activator Myb MYB 17906 nM IC50
TKC146326 Q9HVW7 UDP-N-acetylglucosamine 1-carboxyvinyltransferase murA 10300 nM IC50
TKC146326 P50579 Methionine aminopeptidase 2 METAP2 9 % Inhibition

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P0A749 MURA_ECOLI Bacterial infection [ICD-11: 1A00-1C4Z]
P0A749 MURA_ECOLI Gram-positive bacterial infection [ICD-11: 1B74-1F40]
P50579 MAP2_HUMAN Obesity [ICD-11: 5B80-5B81]
P50579 MAP2_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P50579 MAP2_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
P50579 MAP2_HUMAN Diabetes mellitus [ICD-11: 5A10]