Basic Information

Terpenoid ID TKC146178
Chirality TKC103257
Cell line 0
Protein target 2
DiseaseNCIT 0
ORDO 0
ICD 0

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC146178 RPMI-8226 RPMI 8226; RPMI.8226; RPMI8226; RPMI no. 8226; RPMI no 8226; RPMI #8226; 8226; RPMI 8226/S; RPMI-8226S; RPMI8226/S; 8226/S; Roswell Park Memorial Institute 8226; GM02132; GM2132; GM 2132; GM02132C; Simpson 16600.0 nM IC50 C3242 Orphanet_29073
TKC146178 HT-29 HT 29; HT29 5.0 ug.mL-1 IC50 C4349
TKC146178 A549 1030.0 nM IC50 C3512
TKC146178 MCF7 400.0 nM IC50 C4194
TKC146178 KB KB (HeLa derivative); HeLa-KB; Strain KB 1.0 ug.mL-1 IC50 C27677
TKC146178 HL-60 HL 60; HL.60 HL60; Human Leukemia-60 200.0 nM IC50 C9154 Orphanet_519
TKC146178 SW982 SW-982; SW 982 1280.0 nM IC50 C4279 Orphanet_3273
TKC146178 HeLa HELA; Hela; He La; He-La; HeLa-CCL2; Henrietta Lacks cells; Helacyton gartleri 320.0 nM IC50 C27677
TKC146178 Bel-7402 Bel-7402; BEL 7402; Bel 7402; BEL7402; Bel7402 1160.0 nM IC50 C27677
TKC146178 SGC-7901 SGC 7901; SGC7901 630.0 nM IC50 C27677
TKC146178 HepG2 780.0 nM IC50 C3728 Orphanet_449

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC146178 Q9NPD5 Solute carrier organic anion transporter family member 1B3 SLCO1B3 99 % Inhibition
TKC146178 Q9Y6L6 Solute carrier organic anion transporter family member 1B1 SLCO1B1 112 % Inhibition
TKC146178 P0C6X7 Replicase polyprotein 1ab rep 3100 nM Ki
TKC146178 P22736 Nuclear receptor subfamily 4 group A member 1 NR4A1 960 nM Kd

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11