Basic Information

Terpenoid ID TKC145296
Chirality TKC145295
Cell line 1
Protein target 1
DiseaseNCIT 0
ORDO 0
ICD 6

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC145296 A549 383.0 uM Activity C3512
TKC145296 HepG2 102000.0 nM IC50 C3728 Orphanet_449
TKC145296 WI-38 VA13 WI 38 VA13 subline 2RA; WI 38 VA-13 subline 2RA; WI 38VA13 subline 2RA; WI-38 VA13 sub 2 RA; WI38-VA13 subline 2RA; WI38 VA13/2RA; WI38VA13/2RA; VA13 2RA; WI-38 VA13; WI 38 VA 13; WI38-VA13; WI38/VA13; WI38VA13; VA-13; VA13; AG07217; AG7217 117000.0 nM IC50
TKC145296 WI-38 Wi-38; WI 38; WI38; Wistar Institute-38; AG06814E; AG06814G; AG06814H; AG06814-J; AG06814J; AG06814-M; AG06814-N 7100.0 nM IC50

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC145296 P08183 ATP-dependent translocase ABCB1 ABCB1 104 % Activity

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P08183 MDR1_HUMAN Lung cancer [ICD-11: 2C25]
P08183 MDR1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P08183 MDR1_HUMAN Bacterial infection [ICD-11: 1A00-1C4Z]
P08183 MDR1_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
P08183 MDR1_HUMAN Adrenal cancer [ICD-11: 2D11]
P08183 MDR1_HUMAN Ovarian cancer [ICD-11: 2C73]