Basic Information

Terpenoid ID TKC141510
Chirality TKC106147
Cell line 0
Protein target 2
DiseaseNCIT 0
ORDO 0
ICD 6

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC141510 8505C 8505c 26070.0 nM IC50 C3878 Orphanet_142
TKC141510 A2780 A-2780; 2780; A2780S; A2780par 25540.0 nM IC50 C7979 Orphanet_454723
TKC141510 A-431 A431; A431/P 25280.0 nM IC50 C4819
TKC141510 A549 23500.0 nM IC50 C3512
TKC141510 DLD-1 DLD 1; DLD1; CoCL3 26120.0 nM IC50 C4349
TKC141510 FaDu FaDU; FADU 23410.0 nM IC50 C4043 Orphanet_494547
TKC141510 HCT-116 HCT-116; HCT.116; HCT_116; HCT116; HCT116wt; CoCL2 22100.0 nM IC50 C4910
TKC141510 HCT-8 HCT-8; HCT8 24360.0 nM IC50 C4349
TKC141510 HT-29 HT 29; HT29 27540.0 nM IC50 C4349
TKC141510 MCF7 22140.0 nM IC50 C4194
TKC141510 SW-1736 SW-1736; SW 1736 34870.0 nM IC50 C3878 Orphanet_142
TKC141510 SW480 SW-480; SW 480; SW480E 16080.0 nM IC50 C4349
TKC141510 NIH3T3 NIH/3T3; NIH-3T3; NIH3T3; 3T3; 3T3NIH; 3T3-Swiss; Swiss-3T3; Swiss/3T3; Swiss 3T3; Swiss3T3 22810.0 nM IC50

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC141510 P23141 Liver carboxylesterase 1 CES1 22360 nM IC50
TKC141510 O00748 Cocaine esterase CES2 5610 nM IC50
TKC141510 P00921 Carbonic anhydrase 2 CA2 >10000 nM Ki

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P23141 EST1_HUMAN Peroxisomal disease [ICD-11: 5C57]
P23141 EST1_HUMAN Synthesis disorder [ICD-11: 5C52-5C59]
P23141 EST1_HUMAN Arterial occlusive disease [ICD-11: BD40]
P23141 EST1_HUMAN Hyper-lipoproteinaemia [ICD-11: 5C80]
P23141 EST1_HUMAN Mature B-cell lymphoma [ICD-11: 2A85]
P23141 EST1_HUMAN Chronic arterial occlusive disease [ICD-11: BD4Z]