Basic Information

Terpenoid ID TKC141382
Chirality TKC106092
Cell line 0
Protein target 1
DiseaseNCIT 0
ORDO 0
ICD 7

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC141382 Raji RAJI; P1-Raji; GM04671 50.0 % Activity C27694 Orphanet_543
TKC141382 B16-F10 B16/F10; B16 F10; B16F10; B16 melanoma F10 64700.0 nM IC50 C21790
TKC141382 RAW264.7 RAW264 13800.0 nM IC50 C21604
TKC141382 J774.A1 J-774A.1; J774.A1; J774 A1; J774A.1; J 774A.1; J774 A.1 16800.0 nM IC50 C134780
TKC141382 HT-29 HT 29; HT29 148480.0 nM IC50 C4349
TKC141382 A549 5800.0 nM IC50 C3512
TKC141382 KB KB (HeLa derivative); HeLa-KB; Strain KB 7600.0 nM IC50 C27677

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC141382 P18031 Tyrosine-protein phosphatase non-receptor type 1 PTPN1 21500 nM IC50
TKC141382 Q72874 Protease pol >3400 nM IC50
TKC141382 Q9NPD5 Solute carrier organic anion transporter family member 1B3 SLCO1B3 25 % Inhibition
TKC141382 Q9Y6L6 Solute carrier organic anion transporter family member 1B1 SLCO1B1 37 % Inhibition

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P18031 PTN1_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
P18031 PTN1_HUMAN Acute diabete complication [ICD-11: 5A2Y]
P18031 PTN1_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
P18031 PTN1_HUMAN Obesity [ICD-11: 5B80-5B81]
P18031 PTN1_HUMAN Ophthalmic devices/implants/grafts injury [ICD-11: PK97]
P18031 PTN1_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
P18031 PTN1_HUMAN Metabolic disorder [ICD-11: 5C50-5D2Z]
P18031 PTN1_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]