Basic Information

Terpenoid ID TKC141365
Cell line 2
Protein target 2
DiseaseNCIT 2
ORDO 2
ICD 55

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC141365 HeLa HELA; Hela; He La; He-La; HeLa-CCL2; Henrietta Lacks cells; Helacyton gartleri 22390.0 nM IC50 C27677
TKC141365 A549 26130.0 nM IC50 C3512
TKC141365 HL-60 HL 60; HL.60 HL60; Human Leukemia-60 10780.0 nM IC50 C9154 Orphanet_519
TKC141365 HepG2 12090.0 nM IC50 C3728 Orphanet_449

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC141365 P23219 Prostaglandin G/H synthase 1 PTGS1 >50000 nM IC50
TKC141365 P35354 Prostaglandin G/H synthase 2 PTGS2 >50000 nM IC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P23219 PGH1_HUMAN Alzheimer disease [ICD-11: 8A20]
P23219 PGH1_HUMAN Endometriosis [ICD-11: GA10]
P23219 PGH1_HUMAN Eye anterior segment structural developmental anomaly [ICD-11: LA11]
P23219 PGH1_HUMAN Female pelvic pain [ICD-11: GA34]
P23219 PGH1_HUMAN Hyper-lipoproteinaemia [ICD-11: 5C80]
P23219 PGH1_HUMAN Indeterminate colitis [ICD-11: DD72]
P23219 PGH1_HUMAN Nutritional deficiency [ICD-11: 5B50-5B71]
P23219 PGH1_HUMAN Osteoarthritis [ICD-11: FA00-FA05]
P23219 PGH1_HUMAN Pain [ICD-11: MG30-MG3Z]
P23219 PGH1_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
P23219 PGH1_HUMAN Rheumatoid arthritis [ICD-11: FA20]
P23219 PGH1_HUMAN Seborrhoeic dermatitis [ICD-11: EA81]
P23219 PGH1_HUMAN Tuberculosis [ICD-11: 1B10-1B12]
P23219 PGH1_HUMAN Ulcerative colitis [ICD-11: DD71]
P23219 PGH1_HUMAN Shoulder lesion [ICD-11: FB53]
P23219 PGH1_HUMAN Soft tissue disorder [ICD-11: FB56]
P23219 PGH1_HUMAN Colorectal cancer [ICD-11: 2B91]
P23219 PGH1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P23219 PGH1_HUMAN Systemic sclerosis [ICD-11: 4A42]
P23219 PGH1_HUMAN Vasculitis [ICD-11: 4A44]
P23219 PGH1_HUMAN Ataxic disorder [ICD-11: 8A03]
P23219 PGH1_HUMAN Muscular dystrophy [ICD-11: 8C70]
P23219 PGH1_HUMAN Neuropathy [ICD-11: 8C0Z]
P23219 PGH1_HUMAN Fever [ICD-11: MG26]
P23219 PGH1_HUMAN Gout [ICD-11: FA25]
P23219 PGH1_HUMAN Sensation disturbance [ICD-11: MB40]
P23219 PGH1_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
P23219 PGH1_HUMAN General pain disorder [ICD-11: 8E43]
P35354 PGH2_HUMAN Alzheimer disease [ICD-11: 8A20]
P35354 PGH2_HUMAN Chronic pain [ICD-11: MG30]
P35354 PGH2_HUMAN Endometriosis [ICD-11: GA10]
P35354 PGH2_HUMAN Female pelvic pain [ICD-11: GA34]
P35354 PGH2_HUMAN Hyper-lipoproteinaemia [ICD-11: 5C80]
P35354 PGH2_HUMAN Indeterminate colitis [ICD-11: DD72]
P35354 PGH2_HUMAN Knee osteoarthritis [ICD-11: FA01]
P35354 PGH2_HUMAN Migraine [ICD-11: 8A80]
P35354 PGH2_HUMAN Osteoarthritis [ICD-11: FA00-FA05]
P35354 PGH2_HUMAN Pain [ICD-11: MG30-MG3Z]
P35354 PGH2_HUMAN Rheumatoid arthritis [ICD-11: FA20]
P35354 PGH2_HUMAN Tuberculosis [ICD-11: 1B10-1B12]
P35354 PGH2_HUMAN Shoulder lesion [ICD-11: FB53]
P35354 PGH2_HUMAN Soft tissue disorder [ICD-11: FB56]
P35354 PGH2_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P35354 PGH2_HUMAN Asthma [ICD-11: CA23]
P35354 PGH2_HUMAN Gout [ICD-11: FA25]
P35354 PGH2_HUMAN General pain disorder [ICD-11: 8E43]
P35354 PGH2_HUMAN Lupus erythematosus [ICD-11: 4A40]
P35354 PGH2_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
P35354 PGH2_HUMAN Large intestine polyp [ICD-11: DB35]
P35354 PGH2_HUMAN Lung cancer [ICD-11: 2C25]
P35354 PGH2_HUMAN Pancreatic cancer [ICD-11: 2C10]
P35354 PGH2_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
P35354 PGH2_HUMAN Colorectal cancer [ICD-11: 2B91]
P35354 PGH2_HUMAN Fever [ICD-11: MG26]
P35354 PGH2_HUMAN Malignant haematopoietic neoplasm [ICD-11: 2B33]