Basic Information

Terpenoid ID TKC131482
Cell line 0
Protein target 3
DiseaseNCIT 0
ORDO 0
ICD 11

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC131482 NCI-H460 NCI.H460; H460; H-460; NCIH460; NCI-HUT-460; NCI-460 37300.0 nM IC50 C4450
TKC131482 A549 85300.0 nM IC50 C3512

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC131482 P18031 Tyrosine-protein phosphatase non-receptor type 1 PTPN1 3850 nM IC50
TKC131482 P17706 Tyrosine-protein phosphatase non-receptor type 2 PTPN2 35090 nM IC50
TKC131482 P10586 Receptor-type tyrosine-protein phosphatase F PTPRF <50 % Inhibition
TKC131482 P29350 Tyrosine-protein phosphatase non-receptor type 6 PTPN6 <50 % Inhibition
TKC131482 Q06124 Tyrosine-protein phosphatase non-receptor type 11 PTPN11 <50 % Inhibition
TKC131482 P30305 M-phase inducer phosphatase 2 CDC25B 23230 nM IC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P18031 PTN1_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
P18031 PTN1_HUMAN Acute diabete complication [ICD-11: 5A2Y]
P18031 PTN1_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
P18031 PTN1_HUMAN Obesity [ICD-11: 5B80-5B81]
P18031 PTN1_HUMAN Ophthalmic devices/implants/grafts injury [ICD-11: PK97]
P18031 PTN1_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
P18031 PTN1_HUMAN Metabolic disorder [ICD-11: 5C50-5D2Z]
P18031 PTN1_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
P17706 PTN2_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
Q06124 PTN11_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P30305 MPIP2_HUMAN Lung cancer [ICD-11: 2C25]
P30305 MPIP2_HUMAN Nasopharyngeal cancer [ICD-11: 2B6B]
P30305 MPIP2_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]