Basic Information

Terpenoid ID TKC129004
Chirality TKC100889
Cell line 0
Protein target 12
DiseaseNCIT 0
ORDO 0
ICD 23

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC129004 HepG2 22387.0 nM Potency C3728 Orphanet_449

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC129004 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 TDP1 103 nM Potency
TKC129004 O75874 Isocitrate dehydrogenase [NADP] cytoplasmic IDH1 5 nM Potency
TKC129004 P84022 Mothers against decapentaplegic homolog 3 SMAD3 11220 nM Potency
TKC129004 Q16236 Nuclear factor erythroid 2-related factor 2 NFE2L2 29093 nM Potency
TKC129004 Q99700 Ataxin-2 ATXN2 6310 nM Potency
TKC129004 O75496 Geminin GMNN 184 nM Potency
TKC129004 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1 89125 nM Potency
TKC129004 P00811 Beta-lactamase ampC 794 nM Potency
TKC129004 Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B BAZ2B 79433 nM Potency
TKC129004 P51450 Nuclear receptor ROR-gamma Rorc 11220 nM Potency
TKC129004 O15118 NPC intracellular cholesterol transporter 1 NPC1 8913 nM Potency
TKC129004 P51151 Ras-related protein Rab-9A RAB9A 36 nM Potency

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
O75874 IDHC_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
O75874 IDHC_HUMAN Liver cancer [ICD-11: 2C12]
O75874 IDHC_HUMAN Malignant haematopoietic neoplasm [ICD-11: 2B33]
O75874 IDHC_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
O75874 IDHC_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
O75874 IDHC_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P84022 SMAD3_HUMAN Herpes simplex infection [ICD-11: 1F00]
P84022 SMAD3_HUMAN Kidney fibrosis [ICD-11: GC01]
Q16236 NF2L2_HUMAN Ataxic disorder [ICD-11: 8A03]
Q16236 NF2L2_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
Q16236 NF2L2_HUMAN Glaucoma [ICD-11: 9C61]
Q16236 NF2L2_HUMAN Lung cancer [ICD-11: 2C25]
Q16236 NF2L2_HUMAN Macular degeneration [ICD-11: 9B75]
Q16236 NF2L2_HUMAN Melanoma [ICD-11: 2C30]
Q16236 NF2L2_HUMAN Mental/behavioural/neurodevelopmental disorder [ICD-11: 6E20-6E8Z]
Q16236 NF2L2_HUMAN Pulmonary hypertension [ICD-11: BB01]
Q16236 NF2L2_HUMAN Subarachnoid haemorrhage [ICD-11: 8B01]
Q16236 NF2L2_HUMAN Urinary system clinical sympton [ICD-11: MF8Y]
Q16236 NF2L2_HUMAN Non-alcoholic fatty liver disease [ICD-11: DB92]
Q16236 NF2L2_HUMAN Alpha-1-antitrypsin deficiency [ICD-11: 5C5A]
Q16236 NF2L2_HUMAN Motor neuron disease [ICD-11: 8B60]
Q16236 NF2L2_HUMAN Multiple sclerosis [ICD-11: 8A40]
Q13526 PIN1_HUMAN Lung cancer [ICD-11: 2C25]
Q13526 PIN1_HUMAN Nasopharyngeal cancer [ICD-11: 2B6B]
P51151 RAB9A_HUMAN Fungal infection [ICD-11: 1F29-1F2F]