Basic Information

Terpenoid ID TKC119217
Cell line 0
Protein target 1
DiseaseNCIT 0
ORDO 0
ICD 0

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC119217 DU-4475 Du4475; DU-4475; Du-4475; DU 4475; Du 4475; Duke University 4475 6740.0 nM IC50 C4872
TKC119217 MDA-MB-468 MDA-MB 468; MDA-MB468; MDAMB468; MDA-468; MDA468; MB468; MD Anderson-Metastatic Breast-468 6090.0 nM IC50 C5214
TKC119217 HCT-116 HCT-116; HCT.116; HCT_116; HCT116; HCT116wt; CoCL2 9580.0 nM IC50 C4910
TKC119217 MDA-MB-231 MDA_MB_231; MDA-MB 231; MDA.MB.231; MDA MB 231; MDA MB231; MDA Mb231; MDA-MB231; MDAMB-231; MDAMB231; MDA-231; MDA-231P; MDA231; MDA231-BRE; MB231; MD Anderson-Metastatic Breast-231 13510.0 nM IC50 C5214
TKC119217 DU-145 DU-145; Du-145; DU 145; DU_145; DU.145; Duke University 145 20300.0 nM IC50 C4863

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC119217 P0DTD1 Replicase polyprotein 1ab rep 14 % Inhibition
TKC119217 Q96T53 Ghrelin O-acyltransferase MBOAT4 >1.000e+6 nM IC50
TKC119217 P9WPL4 Steroid C26-monooxygenase cyp142 360 nM Kd
TKC119217 P9WPL4 Steroid C26-monooxygenase cyp142 1200 nM Kd

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
Q96T53 MBOA4_HUMAN Obesity [ICD-11: 5B80-5B81]
Q96T53 MBOA4_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]