Basic Information

Terpenoid ID TKC117541
Chirality TKC206868
Cell line 4
Protein target 1
DiseaseNCIT 4
ORDO 0
ICD 10

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC117541 A549 68.0 nM IC50 C3512
TKC117541 HCC827 HCC-827; HCC 827; HCC0827; Hamon Cancer Center 827 701.0 nM IC50 C3512
TKC117541 CAL-12T Cal-12T; Cal.12T; CAL 12T; CAL12T; Cal12T; CAL 12; Centre Antoine Lacassagne-12T 161.0 nM IC50 C2926
TKC117541 MDA-MB-231 MDA_MB_231; MDA-MB 231; MDA.MB.231; MDA MB 231; MDA MB231; MDA Mb231; MDA-MB231; MDAMB-231; MDAMB231; MDA-231; MDA-231P; MDA231; MDA231-BRE; MB231; MD Anderson-Metastatic Breast-231 1500.0 nM IC50 C5214

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC117541 P06493 Cyclin-dependent kinase 1 CDK1 34 % Activity

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P06493 CDK1_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
P06493 CDK1_HUMAN Lung cancer [ICD-11: 2C25]
P06493 CDK1_HUMAN Mature B-cell lymphoma [ICD-11: 2A85]
P06493 CDK1_HUMAN Nasopharyngeal cancer [ICD-11: 2B6B]
P06493 CDK1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P06493 CDK1_HUMAN Malignant haematopoietic neoplasm [ICD-11: 2B33]
P06493 CDK1_HUMAN Allergic/hypersensitivity disorder [ICD-11: 4A80-4A8Z]
P06493 CDK1_HUMAN Transplant rejection [ICD-11: NE84]
P06493 CDK1_HUMAN Obesity [ICD-11: 5B80-5B81]
P06493 CDK1_HUMAN Pain [ICD-11: MG30-MG3Z]