Basic Information

Terpenoid ID TKC117132
Chirality TKC206860
Cell line 65
Protein target 1
DiseaseNCIT 66
ORDO 23
ICD 0

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC117132 SK-BR-3 SK-Br-3; Sk-Br-3; SK BR 03; SKBR-3; SKBr-3; SK-BR3; SKBr3; SkBr3; SKBR3 1700.0 nM GI50 C5214
TKC117132 MDA-MB-231 MDA_MB_231; MDA-MB 231; MDA.MB.231; MDA MB 231; MDA MB231; MDA Mb231; MDA-MB231; MDAMB-231; MDAMB231; MDA-231; MDA-231P; MDA231; MDA231-BRE; MB231; MD Anderson-Metastatic Breast-231 2100.0 nM GI50 C5214
TKC117132 MCF7 186.0 nM GI50 C4194
TKC117132 T47D 2200.0 nM GI50 C4194
TKC117132 SN12C SN-12C 1040.0 nM GI50 C9385 Orphanet_217071
TKC117132 NCI-H23 NCI.H23; NCI H23; H-23; H23; NCIH23 239.0 nM GI50 C3512
TKC117132 UO-31 UO.31; UO31; U031 587.0 nM GI50 C9385 Orphanet_217071
TKC117132 HOP-92 HOP 92; HOP.92; HOP92; Hop92; Hopkins-92 37.0 nM GI50 C2926
TKC117132 HL-60 HL 60; HL.60 HL60; Human Leukemia-60 46.0 nM GI50 C9154 Orphanet_519
TKC117132 SF-539 SF-539; SF-539 BT; SF.539; SF 539 774.0 nM GI50 C3796 Orphanet_251576
TKC117132 Malme-3M MALME-3M; MALME 3M; Malme-3 M; MALME.3M; Malme3M; MALME3M; Malme-3 Monolayer 330.0 nM GI50 C3224
TKC117132 SK-MEL-5 SK-Mel-5; SK MEL 5; SK.MEL.5; SK-MEL5; SKMel-5; SKMEL-5; SKMEL5; SKMel5; SKmel5; AA-Mel 414.0 nM GI50 C3510
TKC117132 A498 A498 540.0 nM GI50 C9385 Orphanet_217071
TKC117132 K562 K562; K.562; K 562; KO; GM05372; GM05372E 64.0 nM GI50 C9110 Orphanet_521
TKC117132 OVCAR-3 Ovcar-3; OVCAR 3; OVCAR.3; NIH:OVCAR-3; NIH:Ovcar-3; NIH:OVCAR3; NIH-OVCAR-3; NIHOVCAR3; OVCAR3; Ovcar3 78.0 nM GI50 C105555
TKC117132 MOLT-4 Molt-4; MOLT 4; Molt 4; MOLT.4; MOLT4; Molt4; GM02219; GM02219C; GM2219C; GM02219D 140.0 nM GI50 C9142 Orphanet_99861
TKC117132 HOP-62 HOP 62; Hop 62; HOP.62; HOP62; Hop62; Hopkins-62 1107.0 nM GI50 C3512
TKC117132 NCI/ADR-RES NCI/ADR-RES; NCI.ADR.RES; NCIADR.RES; NCI/ADRRES; NCIADRRES; ADR-RES; MCF-7/ADR; MCF-7/ADR-RES; MCF-7/AdrR; MCF-7/Adr; MCF-7/adr; MCF-7ADR; MCF7-ADR; MCF7ADR; OVCAR-8/ADR; OVCAR8/ADR 6966.0 nM GI50 C105555
TKC117132 U-251 U-251 MG; U-251-MG; U-251_MG; U251-MG; U251MG; U-251; U251; U251n; U251N; 251 MG; 251MG; 251 MG(6) 1884.0 nM GI50 C60781 Orphanet_94
TKC117132 OVCAR-5 OVCAR 5; NIH:OVCAR-5; OVCAR.5; OVCAR5; Ovcar5; OVCA5 1972.0 nM GI50 C105555
TKC117132 OVCAR-8 OVCAR 8; NIH:OVCAR-8; OVCAR8; Ovcar8; OVCAR.8; OVCA8 98.0 nM GI50 C105555
TKC117132 DMS-273 DMS-273; DMS273; Darmouth Medical School 273 614.0 nM GI50 C4917 Orphanet_70573
TKC117132 SNB-19 SNB.19; SNB19; Surgical Neurology Branch-19 2173.0 nM GI50 C60781 Orphanet_94
TKC117132 M19-MEL M-19; M19 169.0 nM GI50 C3802
TKC117132 SW-620 SW-620; SW 620; SW.620 133.0 nM GI50 C4349
TKC117132 KM12 KM-12; KM.12 728.0 nM GI50 C4910
TKC117132 NCI-H522 NCI.H522; H522; H-522; NCI-522; NCI522; NCIH522 52.0 nM GI50 C3512
TKC117132 XF498 XF-498; XF498 91.0 nM GI50 C3058 Orphanet_360
TKC117132 NCI-H322M NCI.H322M; H322M; H-322M; H-322m 1156.0 nM GI50 C2923
TKC117132 RPMI-8226 RPMI 8226; RPMI.8226; RPMI8226; RPMI no. 8226; RPMI no 8226; RPMI #8226; 8226; RPMI 8226/S; RPMI-8226S; RPMI8226/S; 8226/S; Roswell Park Memorial Institute 8226; GM02132; GM2132; GM 2132; GM02132C; Simpson 96.0 nM GI50 C3242 Orphanet_29073
TKC117132 OVCAR-4 OVCAR 4; NIH:OVCAR-4; NIH:OVCAR4; OVCAR.4; OVCAR4; Ovcar4 195.0 nM GI50 C105555
TKC117132 LOX IMVI LOX/IMVI; LOX IMVI; LOXIM-VI; LOXIMVI; LOX 133.0 nM GI50 C3802
TKC117132 P388 P-388 103.0 nM GI50 C21602
TKC117132 KM-20L2 KM-20L2; KM 20L2; KM 2012 160.0 nM GI50 C4349
TKC117132 SK-MEL-2 SK-Mel-2; SK-Mel 2; SK-mel-2; SK-MEL2; SK.MEL.2; SK Mel 2; SK MEL 2; SKMEL-2; SKMEL2; SKmel2; SK-ML2; SKml2 451.0 nM GI50 C3224
TKC117132 A549 4009.0 nM GI50 C3512
TKC117132 HCC 2998 HCC-2998; HCC.2998; HCC 2998; Hamon Cancer Center 2998 1706.0 nM GI50 C4349
TKC117132 SNB-75 SNB.75; SNB75; Surgical Neurology Branch-75 47.0 nM GI50 C3058 Orphanet_360
TKC117132 HCT-15 HCT-15; HCT.15; HCT15 137.0 nM GI50 C4349
TKC117132 HCT-116 HCT-116; HCT.116; HCT_116; HCT116; HCT116wt; CoCL2 182.0 nM GI50 C4910
TKC117132 SF-268 SF-268; SF.268; SF 268 703.0 nM GI50 C60781 Orphanet_94
TKC117132 EKVX 637.0 nM GI50 C3512
TKC117132 DMS-114 DMS-114; DMS114; Darmouth Medical School 114 72.0 nM GI50 C4917 Orphanet_70573
TKC117132 SK-OV-3 SKOV-3; SK-OV3; SK.OV.3; SKOV3; Skov3; SKO3 6397.0 nM GI50 C7978
TKC117132 NCI-H460 NCI.H460; H460; H-460; NCIH460; NCI-HUT-460; NCI-460 1600.0 nM GI50 C4450
TKC117132 UACC-62 UACC 62; UACC.62; UACC62; University of Arizona Cell Culture-62 115.0 nM GI50 C3224
TKC117132 CAKI-1 CAL 1; Centre Antoine Lacassagne-1 25.0 nM GI50 C3224
TKC117132 P388/ADR 1104.0 nM GI50 C21602
TKC117132 SF-295 SF-295; SF.295; SF 295 2992.0 nM GI50 C3058 Orphanet_360
TKC117132 IGROV-1 Igrov-1; IGROV 1; IGR-OV1; IGROV1; Igrov1; IGR.OV1; IGROV; OV1/P; OV1/p; OV1-P 1009.0 nM GI50 C7979 Orphanet_454723
TKC117132 UACC-257 UACC 257; UACC.257; UACC257; University of Arizona Cell Culture-257 308.0 nM GI50 C3224
TKC117132 SNB-78 SNB78; Surgical Neurology Branch-78 499.0 nM GI50 C3058 Orphanet_360
TKC117132 DLD-1 DLD 1; DLD1; CoCL3 231.0 nM GI50 C4349
TKC117132 CCRF-CEM CCRF/CEM; CCRFCEM; CCRF.CEM; CCRF CEM; CCRF; CEM; CEM-CCRF; CEM-CCRF (CAMR); CCRF/CEM/0; CEM/0; CEM-0; CCRF-CEM/S; GM03671; GM03671C 85.0 nM GI50 C7953 Orphanet_99861
TKC117132 NCI-H226 NCI.H226; NCI H226; H226; H-226; HUT-226; HUT 226; NCIH226 10990.0 nM GI50 C45662 Orphanet_50251
TKC117132 HT-29 HT 29; HT29 174.0 nM GI50 C4349
TKC117132 SK-MEL-28 SK-Mel-28; SK.MEL.28; SK-MEL 28; SK MEL-28; SK MEL 28; SK Mel 28; SKMel-28; SKMEL-28; SK-MEL28; SK-Mel28; SK Mel28; SKMEL28; SKMel28; SKmel28; SKML-28; SK28; AU-Mel; P-36; P36 2000.0 nM IC50 C3510
TKC117132 RXF 393 RXF393L; RXF-393 L; RXF-393; RXF 393; RXF.393; RXF393; RXF 393NL 96.0 nM GI50 C9385 Orphanet_217071
TKC117132 COLO 205 Colo 205; CoLo 205; COLO-205; Colo-205; COLO.205; Colo205; COLO205; Co 205; Colorado 205 54.0 nM GI50 C4349
TKC117132 HOP-18 HOP 18; Hop 18; HOP18; Hop18; Hopkins-18 45.0 nM GI50 C4450
TKC117132 SN12K1 4112.0 nM GI50 C9385 Orphanet_217071
TKC117132 HEK293 89.0 % Survival
TKC117132 RAW264.7 RAW264 320.0 nM IC50 C21604
TKC117132 ACHN 563.0 nM IC50 C6975 Orphanet_319298
TKC117132 LNCaP LNCAP; LNCap; Ln-Cap; Lymph Node Carcinoma of the prostate 160.0 nM IC50 C4863
TKC117132 CWR22R 22RV1; 22Rv-1; 22rV1; CWR-22rv1; CWR22-Rv1; CWR22R-V1; CWR22-R1; CWR22Rv1; CWR22R 90.0 nM IC50 C4863

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC117132 Q9WKE8 Reverse transcriptase reverse transcriptase >200 ug.mL-1 IC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11