Basic Information

Terpenoid ID TKC116328
Cell line 0
Protein target 1
DiseaseNCIT 0
ORDO 0
ICD 7

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC116328 SH-SY5Y SH-Sy5y; SHSY5Y; SHSY-5Y; SK-SH-SY5Y; SY5Y; SH-SY5Y Parental 11.0 % Activity C3270 Orphanet_635

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC116328 P18031 Tyrosine-protein phosphatase non-receptor type 1 PTPN1 3800 nM IC50
TKC116328 P17706 Tyrosine-protein phosphatase non-receptor type 2 PTPN2 <50 % Inhibition
TKC116328 P10586 Receptor-type tyrosine-protein phosphatase F PTPRF <50 % Inhibition
TKC116328 P29350 Tyrosine-protein phosphatase non-receptor type 6 PTPN6 <50 % Inhibition
TKC116328 Q06124 Tyrosine-protein phosphatase non-receptor type 11 PTPN11 <50 % Inhibition
TKC116328 P30305 M-phase inducer phosphatase 2 CDC25B <50 % Inhibition

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P18031 PTN1_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
P18031 PTN1_HUMAN Acute diabete complication [ICD-11: 5A2Y]
P18031 PTN1_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
P18031 PTN1_HUMAN Obesity [ICD-11: 5B80-5B81]
P18031 PTN1_HUMAN Ophthalmic devices/implants/grafts injury [ICD-11: PK97]
P18031 PTN1_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
P18031 PTN1_HUMAN Metabolic disorder [ICD-11: 5C50-5D2Z]
P18031 PTN1_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
P17706 PTN2_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
Q06124 PTN11_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P30305 MPIP2_HUMAN Lung cancer [ICD-11: 2C25]
P30305 MPIP2_HUMAN Nasopharyngeal cancer [ICD-11: 2B6B]
P30305 MPIP2_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]