Basic Information

Terpenoid ID TKC114457
Cell line 9
Protein target 1
DiseaseNCIT 10
ORDO 7
ICD 2

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC114457 SN12C SN-12C 41210.0 nM GI50 C9385 Orphanet_217071
TKC114457 MDA-N MDAN 28907.0 nM GI50 C3802
TKC114457 ACHN 53580.0 nM GI50 C6975 Orphanet_319298
TKC114457 UO-31 UO.31; UO31; U031 22491.0 nM GI50 C9385 Orphanet_217071
TKC114457 DU-145 DU-145; Du-145; DU 145; DU_145; DU.145; Duke University 145 30269.0 nM GI50 C4863
TKC114457 HL-60 HL 60; HL.60 HL60; Human Leukemia-60 13366.0 nM GI50 C9154 Orphanet_519
TKC114457 SK-MEL-5 SK-Mel-5; SK MEL 5; SK.MEL.5; SK-MEL5; SKMel-5; SKMEL-5; SKMEL5; SKMel5; SKmel5; AA-Mel 33037.0 nM GI50 C3510
TKC114457 SF-539 SF-539; SF-539 BT; SF.539; SF 539 25293.0 nM GI50 C3796 Orphanet_251576
TKC114457 K562 K562; K.562; K 562; KO; GM05372; GM05372E 23878.0 nM GI50 C9110 Orphanet_521
TKC114457 MOLT-4 Molt-4; MOLT 4; Molt 4; MOLT.4; MOLT4; Molt4; GM02219; GM02219C; GM2219C; GM02219D 20749.0 nM GI50 C9142 Orphanet_99861
TKC114457 NCI/ADR-RES NCI/ADR-RES; NCI.ADR.RES; NCIADR.RES; NCI/ADRRES; NCIADRRES; ADR-RES; MCF-7/ADR; MCF-7/ADR-RES; MCF-7/AdrR; MCF-7/Adr; MCF-7/adr; MCF-7ADR; MCF7-ADR; MCF7ADR; OVCAR-8/ADR; OVCAR8/ADR 100000.0 nM GI50 C105555
TKC114457 HOP-62 HOP 62; Hop 62; HOP.62; HOP62; Hop62; Hopkins-62 63533.0 nM GI50 C3512
TKC114457 U-251 U-251 MG; U-251-MG; U-251_MG; U251-MG; U251MG; U-251; U251; U251n; U251N; 251 MG; 251MG; 251 MG(6) 30761.0 nM GI50 C60781 Orphanet_94
TKC114457 OVCAR-8 OVCAR 8; NIH:OVCAR-8; OVCAR8; Ovcar8; OVCAR.8; OVCA8 31261.0 nM GI50 C105555
TKC114457 OVCAR-5 OVCAR 5; NIH:OVCAR-5; OVCAR.5; OVCAR5; Ovcar5; OVCA5 25527.0 nM GI50 C105555
TKC114457 SNB-19 SNB.19; SNB19; Surgical Neurology Branch-19 3236.0 nM GI50 C60781 Orphanet_94
TKC114457 MDA-MB-231 MDA_MB_231; MDA-MB 231; MDA.MB.231; MDA MB 231; MDA MB231; MDA Mb231; MDA-MB231; MDAMB-231; MDAMB231; MDA-231; MDA-231P; MDA231; MDA231-BRE; MB231; MD Anderson-Metastatic Breast-231 28840.0 nM GI50 C5214
TKC114457 TK-10 TK.10; TK 10; TK10 36898.0 nM GI50 C4033 Orphanet_319276
TKC114457 SR SR-786; SR786 18197.0 nM GI50 C37193 Orphanet_300895
TKC114457 SW-620 SW-620; SW 620; SW.620 40179.0 nM GI50 C4349
TKC114457 KM12 KM-12; KM.12 26607.0 nM GI50 C4910
TKC114457 M14 M14-MEL; UCLA-SO-M14; UCLA SO M14; UCLA-SO-14; UCLASO-M14; Melanoma 14; M-14 21577.0 nM GI50 C3802
TKC114457 RPMI-8226 RPMI 8226; RPMI.8226; RPMI8226; RPMI no. 8226; RPMI no 8226; RPMI #8226; 8226; RPMI 8226/S; RPMI-8226S; RPMI8226/S; 8226/S; Roswell Park Memorial Institute 8226; GM02132; GM2132; GM 2132; GM02132C; Simpson 19724.0 nM GI50 C3242 Orphanet_29073
TKC114457 OVCAR-4 OVCAR 4; NIH:OVCAR-4; NIH:OVCAR4; OVCAR.4; OVCAR4; Ovcar4 27797.0 nM GI50 C105555
TKC114457 SK-MEL-2 SK-Mel-2; SK-Mel 2; SK-mel-2; SK-MEL2; SK.MEL.2; SK Mel 2; SK MEL 2; SKMEL-2; SKMEL2; SKmel2; SK-ML2; SKml2 17906.0 nM GI50 C3224
TKC114457 A549 40832.0 nM GI50 C3512
TKC114457 HCC 2998 HCC-2998; HCC.2998; HCC 2998; Hamon Cancer Center 2998 39084.0 nM GI50 C4349
TKC114457 SNB-75 SNB.75; SNB75; Surgical Neurology Branch-75 15668.0 nM GI50 C3058 Orphanet_360
TKC114457 HCT-15 HCT-15; HCT.15; HCT15 34356.0 nM GI50 C4349
TKC114457 HCT-116 HCT-116; HCT.116; HCT_116; HCT116; HCT116wt; CoCL2 20701.0 nM GI50 C4910
TKC114457 SF-268 SF-268; SF.268; SF 268 26669.0 nM GI50 C60781 Orphanet_94
TKC114457 EKVX 40551.0 nM GI50 C3512
TKC114457 PC-3 PC3; PC.3 35975.0 nM GI50 C4863
TKC114457 MCF7 36308.0 nM GI50 C4194
TKC114457 SK-OV-3 SKOV-3; SK-OV3; SK.OV.3; SKOV3; Skov3; SKO3 46989.0 nM GI50 C7978
TKC114457 T47D 31261.0 nM GI50 C4194
TKC114457 NCI-H460 NCI.H460; H460; H-460; NCIH460; NCI-HUT-460; NCI-460 29854.0 nM GI50 C4450
TKC114457 CAKI-1 CAL 1; Centre Antoine Lacassagne-1 21281.0 nM GI50 C3224
TKC114457 UACC-62 UACC 62; UACC.62; UACC62; University of Arizona Cell Culture-62 22029.0 nM GI50 C3224
TKC114457 MDA-MB-435 MDA-MB435; MDAMB435; MDA.MB.435; MDA-435; MDA 435; MDA435; MD Anderson-Metastatic Breast-435 20370.0 nM GI50 C3802
TKC114457 SF-295 SF-295; SF.295; SF 295 33343.0 nM GI50 C3058 Orphanet_360
TKC114457 IGROV-1 Igrov-1; IGROV 1; IGR-OV1; IGROV1; Igrov1; IGR.OV1; IGROV; OV1/P; OV1/p; OV1-P 42267.0 nM GI50 C7979 Orphanet_454723
TKC114457 786-0 786-o; 786O; 786-0; 786.O; 786-O RCC; RCC 786-O; RCC_7860; RCC 7860; 7860; 786-0WT 33113.0 nM GI50 C9385 Orphanet_217071
TKC114457 Hs-578T HS 578T; Hs-578T; HS-578T; Hs_578t; Hs-578-T; HS-578-T; Hs 578.T; HS578T; Hs578T; Hs578t; HS0578T; 578T; HS578; Hs578; Homo sapiens No. 578, tumor cells 20893.0 nM GI50 C4194
TKC114457 UACC-257 UACC 257; UACC.257; UACC257; University of Arizona Cell Culture-257 30974.0 nM GI50 C3224
TKC114457 CCRF-CEM CCRF/CEM; CCRFCEM; CCRF.CEM; CCRF CEM; CCRF; CEM; CEM-CCRF; CEM-CCRF (CAMR); CCRF/CEM/0; CEM/0; CEM-0; CCRF-CEM/S; GM03671; GM03671C 13646.0 nM GI50 C7953 Orphanet_99861
TKC114457 HT-29 HT 29; HT29 33963.0 nM GI50 C4349
TKC114457 SK-MEL-28 SK-Mel-28; SK.MEL.28; SK-MEL 28; SK MEL-28; SK MEL 28; SK Mel 28; SKMel-28; SKMEL-28; SK-MEL28; SK-Mel28; SK Mel28; SKMEL28; SKMel28; SKmel28; SKML-28; SK28; AU-Mel; P-36; P36 22182.0 nM GI50 C3510
TKC114457 RXF 393 RXF393L; RXF-393 L; RXF-393; RXF 393; RXF.393; RXF393; RXF 393NL 13804.0 nM GI50 C9385 Orphanet_217071
TKC114457 COLO 205 Colo 205; CoLo 205; COLO-205; Colo-205; COLO.205; Colo205; COLO205; Co 205; Colorado 205 33963.0 nM GI50 C4349
TKC114457 RAW264.7 RAW264 17110.0 nM IC50 C21604

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC114457 P25963 NF-kappa-B inhibitor alpha NFKBIA >50000 nM IC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P25963 IKBA_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
P25963 IKBA_HUMAN Metabolic disorder [ICD-11: 5C50-5D2Z]