Basic Information

Terpenoid ID TKC114430
Cell line 0
Protein target 2
DiseaseNCIT 0
ORDO 0
ICD 2

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC114430 LNCaP LNCAP; LNCap; Ln-Cap; Lymph Node Carcinoma of the prostate 5.0 ug.mL-1 EC50 C4863
TKC114430 KB KB (HeLa derivative); HeLa-KB; Strain KB 3.0 ug.mL-1 EC50 C27677
TKC114430 A-431 A431; A431/P 2.0 ug.mL-1 EC50 C4819
TKC114430 A549 6.0 ug.mL-1 EC50 C3512
TKC114430 HCT-8 HCT-8; HCT8 2.0 ug.mL-1 EC50 C4349
TKC114430 PC-3 PC3; PC.3 1.0 ug.mL-1 EC50 C4863
TKC114430 ZR-75-1 Zr-75-1; ZR751; ZR75-1; ZR75.1; ZR75_1 3.0 ug.mL-1 EC50 C4194
TKC114430 RAW264.7 RAW264 840.0 nM IC50 C21604
TKC114430 HeLa HELA; Hela; He La; He-La; HeLa-CCL2; Henrietta Lacks cells; Helacyton gartleri 2000.0 nM IC50 C27677
TKC114430 Jurkat JURKAT; JM; JM-Jurkat; Jurkat-FHCRC; Jurkat FHCRC; FHCRC-11; FHCRC subclone 11; FCCH1024 2.0 % Activity C7953 Orphanet_99861

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC114430 P08151 Zinc finger protein GLI1 GLI1 620 nM IC50
TKC114430 P25963 NF-kappa-B inhibitor alpha NFKBIA 37500 nM IC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P25963 IKBA_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
P25963 IKBA_HUMAN Metabolic disorder [ICD-11: 5C50-5D2Z]