Basic Information

Terpenoid ID TKC113159
Chirality TKC206782
Cell line 0
Protein target 10
DiseaseNCIT 0
ORDO 0
ICD 7

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC113159 P388 P-388 8.0 ug ml-1 ED50 C21602
TKC113159 A549 9.0 ug ml-1 ED50 C3512
TKC113159 HT-29 HT 29; HT29 1.0 ug ml-1 ED50 C4349

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC113159 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 TDP1 25929 nM Potency
TKC113159 Q9NPD5 Solute carrier organic anion transporter family member 1B3 SLCO1B3 110 % Inhibition
TKC113159 Q9Y6L6 Solute carrier organic anion transporter family member 1B1 SLCO1B1 82 % Inhibition
TKC113159 Q9UNA4 DNA polymerase iota POLI 100000 nM Potency
TKC113159 P0DTD1 Replicase polyprotein 1ab rep 15 % Inhibition
TKC113159 P00811 Beta-lactamase ampC 316 nM Potency
TKC113159 P63096 Guanine nucleotide-binding protein G GNAI1 50119 nM Potency
TKC113159 P49798 Regulator of G-protein signaling 4 RGS4 8437 nM Potency
TKC113159 P02545 Prelamin-A/C LMNA 35481 nM Potency
TKC113159 P22310 UDP-glucuronosyltransferase 1A4 UGT1A4 72 pm/min/mg Activity
TKC113159 Q9HAW8 UDP-glucuronosyltransferase 1A10 UGT1A10 0 pm/min/mg Activity
TKC113159 Q9HAW9 UDP-glucuronosyltransferase 1A8 UGT1A8 0 pm/min/mg Activity
TKC113159 P16662 UDP-glucuronosyltransferase 2B7 UGT2B7 5 total picomoles Activity
TKC113159 P97697 Inositol monophosphatase 1 Impa1 19953 nM Potency
TKC113159 O35627 Nuclear receptor subfamily 1 group I member 3 Nr1i3 95 % Remaining activity
TKC113159 P04278 Sex hormone-binding globulin SHBG 71 nM Kd
TKC113159 P08185 Corticosteroid-binding globulin SERPINA6 5888 nM Ki
TKC113159 P56937 3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7 HSD17B7 13 % Inhibition
TKC113159 Q16850 Lanosterol 14-alpha demethylase CYP51A1 >200000 nM IC50
TKC113159 P11413 Glucose-6-phosphate 1-dehydrogenase G6PD 81400 nM IC50
TKC113159 O75795 UDP-glucuronosyltransferase 2B17 UGT2B17 0 pm/min/mg Activity
TKC113159 Q9Y6A2 Cholesterol 24-hydroxylase CYP46A1 32 % Activity

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P08185 CBG_HUMAN Asthma [ICD-11: CA23]
P08185 CBG_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
P08185 CBG_HUMAN Respiratory system disease [ICD-11: CB40-CB7Z]
P08185 CBG_HUMAN Retinopathy [ICD-11: 9B71]
Q16850 CP51A_HUMAN Infectious meningitis [ICD-11: 1D01]
Q16850 CP51A_HUMAN Nail/perionychium infection [ICD-11: EE12]
Q16850 CP51A_HUMAN Onchocerciasis [ICD-11: 1F6A]
P11413 G6PD_HUMAN Cardiovascular disease [ICD-11: BA00-BE2Z]
P11413 G6PD_HUMAN Chronic obstructive pulmonary disease [ICD-11: CA22]
P11413 G6PD_HUMAN Rheumatoid arthritis [ICD-11: FA20]
Q9Y6A2 CP46A_HUMAN Acidosis [ICD-11: 5C73]
Q9Y6A2 CP46A_HUMAN Epilepsy/seizure [ICD-11: 8A61-8A6Z]
Q9Y6A2 CP46A_HUMAN Epileptic encephalopathy [ICD-11: 8A62]
Q9Y6A2 CP46A_HUMAN Phakomatoses/hamartoneoplastic syndrome [ICD-11: LD2D]
Q9Y6A2 CP46A_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]