Basic Information

Terpenoid ID TKC112366
Chirality TKC206738
Cell line 72
Protein target 0
DiseaseNCIT 74
ORDO 26
ICD 0

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC112366 EKVX 24.0 nM GI50 C3512
TKC112366 SF-268 SF-268; SF.268; SF 268 2.0 nM GI50 C60781 Orphanet_94
TKC112366 KB KB (HeLa derivative); HeLa-KB; Strain KB 41.0 nM IC50 C27677
TKC112366 NCI-H187 H187; H-187; NCIH187 345.0 nM IC50 C4917 Orphanet_70573
TKC112366 PC-3 PC3; PC.3 20.0 nM IC50 C4863
TKC112366 BXPC-3 BxPc-3; BXPC-3; Bx-PC3; BXPC3; BxPC3; BxPc3; Biopsy xenograft of Pancreatic Carcinoma line-3 80.0 nM IC50 C9120
TKC112366 LoVo LOVO 50.0 nM IC50 C4349
TKC112366 SN12C SN-12C 3.0 nM GI50 C9385 Orphanet_217071
TKC112366 MDA-N MDAN 54.0 nM GI50 C3802
TKC112366 ACHN 3.0 nM GI50 C6975 Orphanet_319298
TKC112366 NCI-H23 NCI.H23; NCI H23; H-23; H23; NCIH23 2.0 nM GI50 C3512
TKC112366 UO-31 UO.31; UO31; U031 17.0 nM GI50 C9385 Orphanet_217071
TKC112366 HOP-92 HOP 92; HOP.92; HOP92; Hop92; Hopkins-92 28.0 nM GI50 C2926
TKC112366 HL-60 HL 60; HL.60 HL60; Human Leukemia-60 13.0 nM GI50 C9154 Orphanet_519
TKC112366 DU-145 DU-145; Du-145; DU 145; DU_145; DU.145; Duke University 145 17.0 nM GI50 C4863
TKC112366 SF-539 SF-539; SF-539 BT; SF.539; SF 539 6.0 nM GI50 C3796 Orphanet_251576
TKC112366 SK-MEL-5 SK-Mel-5; SK MEL 5; SK.MEL.5; SK-MEL5; SKMel-5; SKMEL-5; SKMEL5; SKMel5; SKmel5; AA-Mel 10.0 nM GI50 C3510
TKC112366 Malme-3M MALME-3M; MALME 3M; Malme-3 M; MALME.3M; Malme3M; MALME3M; Malme-3 Monolayer 12.0 nM GI50 C3224
TKC112366 K562 K562; K.562; K 562; KO; GM05372; GM05372E 18.0 nM GI50 C9110 Orphanet_521
TKC112366 A498 A498 21.0 nM GI50 C9385 Orphanet_217071
TKC112366 OVCAR-3 Ovcar-3; OVCAR 3; OVCAR.3; NIH:OVCAR-3; NIH:Ovcar-3; NIH:OVCAR3; NIH-OVCAR-3; NIHOVCAR3; OVCAR3; Ovcar3 2.0 nM GI50 C105555
TKC112366 MOLT-4 Molt-4; MOLT 4; Molt 4; MOLT.4; MOLT4; Molt4; GM02219; GM02219C; GM2219C; GM02219D 2.0 nM GI50 C9142 Orphanet_99861
TKC112366 HOP-62 HOP 62; Hop 62; HOP.62; HOP62; Hop62; Hopkins-62 7.0 nM GI50 C3512
TKC112366 NCI/ADR-RES NCI/ADR-RES; NCI.ADR.RES; NCIADR.RES; NCI/ADRRES; NCIADRRES; ADR-RES; MCF-7/ADR; MCF-7/ADR-RES; MCF-7/AdrR; MCF-7/Adr; MCF-7/adr; MCF-7ADR; MCF7-ADR; MCF7ADR; OVCAR-8/ADR; OVCAR8/ADR 31.0 nM GI50 C105555
TKC112366 OVCAR-8 OVCAR 8; NIH:OVCAR-8; OVCAR8; Ovcar8; OVCAR.8; OVCA8 11.0 nM GI50 C105555
TKC112366 U-251 U-251 MG; U-251-MG; U-251_MG; U251-MG; U251MG; U-251; U251; U251n; U251N; 251 MG; 251MG; 251 MG(6) 900.0 nM IC50 C60781 Orphanet_94
TKC112366 OVCAR-5 OVCAR 5; NIH:OVCAR-5; OVCAR.5; OVCAR5; Ovcar5; OVCA5 24.0 nM GI50 C105555
TKC112366 SNB-19 SNB.19; SNB19; Surgical Neurology Branch-19 22.0 nM GI50 C60781 Orphanet_94
TKC112366 DMS-273 DMS-273; DMS273; Darmouth Medical School 273 5.0 nM GI50 C4917 Orphanet_70573
TKC112366 SR SR-786; SR786 3.0 nM GI50 C37193 Orphanet_300895
TKC112366 TK-10 TK.10; TK 10; TK10 9.0 nM GI50 C4033 Orphanet_319276
TKC112366 M19-MEL M-19; M19 21.0 nM GI50 C3802
TKC112366 SW-620 SW-620; SW 620; SW.620 13.0 nM GI50 C4349
TKC112366 KM12 KM-12; KM.12 23.0 nM GI50 C4910
TKC112366 NCI-H522 NCI.H522; H522; H-522; NCI-522; NCI522; NCIH522 1.0 nM GI50 C3512
TKC112366 M14 M14-MEL; UCLA-SO-M14; UCLA SO M14; UCLA-SO-14; UCLASO-M14; Melanoma 14; M-14 22.0 nM GI50 C3802
TKC112366 XF498 XF-498; XF498 16.0 nM GI50 C3058 Orphanet_360
TKC112366 NCI-H322M NCI.H322M; H322M; H-322M; H-322m 11.0 nM GI50 C2923
TKC112366 RPMI-8226 RPMI 8226; RPMI.8226; RPMI8226; RPMI no. 8226; RPMI no 8226; RPMI #8226; 8226; RPMI 8226/S; RPMI-8226S; RPMI8226/S; 8226/S; Roswell Park Memorial Institute 8226; GM02132; GM2132; GM 2132; GM02132C; Simpson 28.0 nM GI50 C3242 Orphanet_29073
TKC112366 OVCAR-4 OVCAR 4; NIH:OVCAR-4; NIH:OVCAR4; OVCAR.4; OVCAR4; Ovcar4 22.0 nM GI50 C105555
TKC112366 LOX IMVI LOX/IMVI; LOX IMVI; LOXIM-VI; LOXIMVI; LOX 15.0 nM GI50 C3802
TKC112366 BT-549 BT 549; BT.549; BT549 38.0 nM GI50 C4194
TKC112366 SK-MEL-2 SK-Mel-2; SK-Mel 2; SK-mel-2; SK-MEL2; SK.MEL.2; SK Mel 2; SK MEL 2; SKMEL-2; SKMEL2; SKmel2; SK-ML2; SKml2 11.0 nM GI50 C3224
TKC112366 KM-20L2 KM-20L2; KM 20L2; KM 2012 18.0 nM GI50 C4349
TKC112366 HCC 2998 HCC-2998; HCC.2998; HCC 2998; Hamon Cancer Center 2998 161.0 nM GI50 C4349
TKC112366 SNB-75 SNB.75; SNB75; Surgical Neurology Branch-75 25.0 nM GI50 C3058 Orphanet_360
TKC112366 HCT-116 HCT-116; HCT.116; HCT_116; HCT116; HCT116wt; CoCL2 10.0 nM GI50 C4910
TKC112366 HCT-15 HCT-15; HCT.15; HCT15 16.0 nM GI50 C4349
TKC112366 LXFL 529 LXFL-529L; LXFL529L; LXF 529 L; LXFL-529; LXFL 529; LXFL529; LXF 529 5.0 nM GI50 C2926
TKC112366 DMS-114 DMS-114; DMS114; Darmouth Medical School 114 1.0 nM GI50 C4917 Orphanet_70573
TKC112366 SK-OV-3 SKOV-3; SK-OV3; SK.OV.3; SKOV3; Skov3; SKO3 12.0 nM GI50 C7978
TKC112366 NCI-H460 NCI.H460; H460; H-460; NCIH460; NCI-HUT-460; NCI-460 5.0 nM GI50 C4450
TKC112366 T47D 47.0 nM GI50 C4194
TKC112366 UACC-62 UACC 62; UACC.62; UACC62; University of Arizona Cell Culture-62 16.0 nM GI50 C3224
TKC112366 CAKI-1 CAL 1; Centre Antoine Lacassagne-1 10.0 nM GI50 C3224
TKC112366 SF-295 SF-295; SF.295; SF 295 13.0 nM GI50 C3058 Orphanet_360
TKC112366 MDA-MB-435 MDA-MB435; MDAMB435; MDA.MB.435; MDA-435; MDA 435; MDA435; MD Anderson-Metastatic Breast-435 44.0 nM GI50 C3802
TKC112366 IGROV-1 Igrov-1; IGROV 1; IGR-OV1; IGROV1; Igrov1; IGR.OV1; IGROV; OV1/P; OV1/p; OV1-P 10.0 nM GI50 C7979 Orphanet_454723
TKC112366 Hs-578T HS 578T; Hs-578T; HS-578T; Hs_578t; Hs-578-T; HS-578-T; Hs 578.T; HS578T; Hs578T; Hs578t; HS0578T; 578T; HS578; Hs578; Homo sapiens No. 578, tumor cells 20.0 nM GI50 C4194
TKC112366 786-0 786-o; 786O; 786-0; 786.O; 786-O RCC; RCC 786-O; RCC_7860; RCC 7860; 7860; 786-0WT 6.0 nM GI50 C9385 Orphanet_217071
TKC112366 SNB-78 SNB78; Surgical Neurology Branch-78 11.0 nM GI50 C3058 Orphanet_360
TKC112366 UACC-257 UACC 257; UACC.257; UACC257; University of Arizona Cell Culture-257 21.0 nM GI50 C3224
TKC112366 CCRF-CEM CCRF/CEM; CCRFCEM; CCRF.CEM; CCRF CEM; CCRF; CEM; CEM-CCRF; CEM-CCRF (CAMR); CCRF/CEM/0; CEM/0; CEM-0; CCRF-CEM/S; GM03671; GM03671C 4.0 nM GI50 C7953 Orphanet_99861
TKC112366 DLD-1 DLD 1; DLD1; CoCL3 12.0 nM GI50 C4349
TKC112366 HT-29 HT 29; HT29 21.0 nM GI50 C4349
TKC112366 NCI-H226 NCI.H226; NCI H226; H226; H-226; HUT-226; HUT 226; NCIH226 24.0 nM GI50 C45662 Orphanet_50251
TKC112366 SK-MEL-28 SK-Mel-28; SK.MEL.28; SK-MEL 28; SK MEL-28; SK MEL 28; SK Mel 28; SKMel-28; SKMEL-28; SK-MEL28; SK-Mel28; SK Mel28; SKMEL28; SKMel28; SKmel28; SKML-28; SK28; AU-Mel; P-36; P36 29.0 nM GI50 C3510
TKC112366 COLO 205 Colo 205; CoLo 205; COLO-205; Colo-205; COLO.205; Colo205; COLO205; Co 205; Colorado 205 22.0 nM GI50 C4349
TKC112366 RXF 393 RXF393L; RXF-393 L; RXF-393; RXF 393; RXF.393; RXF393; RXF 393NL 19.0 nM GI50 C9385 Orphanet_217071
TKC112366 HOP-18 HOP 18; Hop 18; HOP18; Hop18; Hopkins-18 4.0 nM GI50 C4450
TKC112366 HeLa HELA; Hela; He La; He-La; HeLa-CCL2; Henrietta Lacks cells; Helacyton gartleri 200.0 nM IC50 C27677
TKC112366 Calu-1 CaLu-1; CALU-1; Calu.1; CALU 1; Calu 1; CALU1; Calu1 500.0 nM IC50 C3493

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11