Basic Information

Terpenoid ID TKC110461
Chirality TKC206693
Cell line 0
Protein target 3
DiseaseNCIT 0
ORDO 0
ICD 3

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC110461 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 TDP1 6513 nM Potency
TKC110461 Q13133 Oxysterols receptor LXR-alpha NR1H3 95 nM EC50
TKC110461 Q13133 Oxysterols receptor LXR-alpha NR1H3 460 nM EC50
TKC110461 Q13133 Oxysterols receptor LXR-alpha NR1H3 500 nM EC50
TKC110461 Q13133 Oxysterols receptor LXR-alpha NR1H3 280 nM EC50
TKC110461 Q13133 Oxysterols receptor LXR-alpha NR1H3 >20000 nM EC50
TKC110461 P55055 Oxysterols receptor LXR-beta NR1H2 168 nM EC50
TKC110461 P55055 Oxysterols receptor LXR-beta NR1H2 286 nM EC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
Q13133 NR1H3_HUMAN Depression [ICD-11: 6A70-6A7Z]
Q13133 NR1H3_HUMAN Depression [ICD-11: 6A70-6A7Z]
Q13133 NR1H3_HUMAN Depression [ICD-11: 6A70-6A7Z]
Q13133 NR1H3_HUMAN Depression [ICD-11: 6A70-6A7Z]
Q13133 NR1H3_HUMAN Depression [ICD-11: 6A70-6A7Z]
P55055 NR1H2_HUMAN Atopic eczema [ICD-11: EA80]
P55055 NR1H2_HUMAN Depression [ICD-11: 6A70-6A7Z]
P55055 NR1H2_HUMAN Atopic eczema [ICD-11: EA80]
P55055 NR1H2_HUMAN Depression [ICD-11: 6A70-6A7Z]