Basic Information

Terpenoid ID TKC109998
Chirality TKC206687
Cell line 0
Protein target 12
DiseaseNCIT 0
ORDO 0
ICD 28

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC109998 HEK293 8196.0 nM Potency

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC109998 P00352 Retinal dehydrogenase 1 ALDH1A1 10000 nM Potency
TKC109998 P10636 Microtubule-associated protein tau MAPT 12589 nM Potency
TKC109998 Q16236 Nuclear factor erythroid 2-related factor 2 NFE2L2 32643 nM Potency
TKC109998 O89049 Thioredoxin reductase 1, cytoplasmic Txnrd1 37686 nM Potency
TKC109998 P0DTD1 Replicase polyprotein 1ab rep 24 % Inhibition
TKC109998 Q96KQ7 Histone-lysine N-methyltransferase EHMT2 EHMT2 891 nM Potency
TKC109998 Q01453 Peripheral myelin protein 22 PMP22 95283 nM Potency
TKC109998 P49798 Regulator of G-protein signaling 4 RGS4 37686 nM Potency
TKC109998 Q03164 Histone-lysine N-methyltransferase 2A KMT2A 36 nM Potency
TKC109998 P10063 Gamma-aminobutyric acid receptor subunit alpha-2 GABRA2 300 nM POT
TKC109998 P15289 Arylsulfatase A ARSA 2393 nM Potency
TKC109998 O09028 Gamma-aminobutyric acid receptor subunit pi Gabrp 39 nM IC50
TKC109998 P11413 Glucose-6-phosphate 1-dehydrogenase G6PD 31600 nM IC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P10636 TAU_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
P10636 TAU_HUMAN Alzheimer disease [ICD-11: 8A20]
P10636 TAU_HUMAN Mild neurocognitive disorder [ICD-11: 6D71]
P10636 TAU_HUMAN Choreiform disorder [ICD-11: 8A01]
P10636 TAU_HUMAN Parkinsonism [ICD-11: 8A00]
P10636 TAU_HUMAN Central nervous system disease [ICD-11: 8A04-8D87]
P10636 TAU_HUMAN Neurodegenerative disorder [ICD-11: 8A20-8A23]
Q16236 NF2L2_HUMAN Ataxic disorder [ICD-11: 8A03]
Q16236 NF2L2_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
Q16236 NF2L2_HUMAN Glaucoma [ICD-11: 9C61]
Q16236 NF2L2_HUMAN Lung cancer [ICD-11: 2C25]
Q16236 NF2L2_HUMAN Macular degeneration [ICD-11: 9B75]
Q16236 NF2L2_HUMAN Melanoma [ICD-11: 2C30]
Q16236 NF2L2_HUMAN Mental/behavioural/neurodevelopmental disorder [ICD-11: 6E20-6E8Z]
Q16236 NF2L2_HUMAN Pulmonary hypertension [ICD-11: BB01]
Q16236 NF2L2_HUMAN Subarachnoid haemorrhage [ICD-11: 8B01]
Q16236 NF2L2_HUMAN Urinary system clinical sympton [ICD-11: MF8Y]
Q16236 NF2L2_HUMAN Non-alcoholic fatty liver disease [ICD-11: DB92]
Q16236 NF2L2_HUMAN Alpha-1-antitrypsin deficiency [ICD-11: 5C5A]
Q16236 NF2L2_HUMAN Motor neuron disease [ICD-11: 8B60]
Q16236 NF2L2_HUMAN Multiple sclerosis [ICD-11: 8A40]
Q96KQ7 EHMT2_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
Q96KQ7 EHMT2_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
Q96KQ7 EHMT2_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P15289 ARSA_HUMAN Lysosomal disease [ICD-11: 5C56]
P11413 G6PD_HUMAN Cardiovascular disease [ICD-11: BA00-BE2Z]
P11413 G6PD_HUMAN Chronic obstructive pulmonary disease [ICD-11: CA22]
P11413 G6PD_HUMAN Rheumatoid arthritis [ICD-11: FA20]