Basic Information

Terpenoid ID TKC106013
Cell line 0
Protein target 9
DiseaseNCIT 0
ORDO 0
ICD 11

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC106013 HCT-116 HCT-116; HCT.116; HCT_116; HCT116; HCT116wt; CoCL2 2.0 nM IC50 C4910

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC106013 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 TDP1 73 nM Potency
TKC106013 O75874 Isocitrate dehydrogenase [NADP] cytoplasmic IDH1 37 nM Potency
TKC106013 P84022 Mothers against decapentaplegic homolog 3 SMAD3 7943 nM Potency
TKC106013 Q99700 Ataxin-2 ATXN2 1000 nM Potency
TKC106013 Q9UNA4 DNA polymerase iota POLI 89125 nM Potency
TKC106013 O75496 Geminin GMNN 65 nM Potency
TKC106013 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1 89125 nM Potency
TKC106013 Q96KQ7 Histone-lysine N-methyltransferase EHMT2 EHMT2 100000 nM Potency
TKC106013 P51450 Nuclear receptor ROR-gamma Rorc 3162 nM Potency

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
O75874 IDHC_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
O75874 IDHC_HUMAN Liver cancer [ICD-11: 2C12]
O75874 IDHC_HUMAN Malignant haematopoietic neoplasm [ICD-11: 2B33]
O75874 IDHC_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
O75874 IDHC_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
O75874 IDHC_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P84022 SMAD3_HUMAN Herpes simplex infection [ICD-11: 1F00]
P84022 SMAD3_HUMAN Kidney fibrosis [ICD-11: GC01]
Q13526 PIN1_HUMAN Lung cancer [ICD-11: 2C25]
Q13526 PIN1_HUMAN Nasopharyngeal cancer [ICD-11: 2B6B]
Q96KQ7 EHMT2_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
Q96KQ7 EHMT2_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
Q96KQ7 EHMT2_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]