Basic Information

Terpenoid ID TKC105753
Chirality TKC062672
Cell line 0
Protein target 9
DiseaseNCIT 0
ORDO 0
ICD 6

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC105753 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 TDP1 1636 nM Potency
TKC105753 O75874 Isocitrate dehydrogenase [NADP] cytoplasmic IDH1 29093 nM Potency
TKC105753 P84022 Mothers against decapentaplegic homolog 3 SMAD3 3264 nM Potency
TKC105753 Q06710 Paired box protein Pax-8 PAX8 7140 nM AC50
TKC105753 Q99700 Ataxin-2 ATXN2 3162 nM Potency
TKC105753 Q9UNA4 DNA polymerase iota POLI 28184 nM Potency
TKC105753 O75496 Geminin GMNN 920 nM Potency
TKC105753 Q96QE3 ATPase family AAA domain-containing protein 5 ATAD5 18349 nM Potency
TKC105753 Q9Y468 Lethal(3)malignant brain tumor-like protein 1 L3MBTL1 25119 nM Potency

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
O75874 IDHC_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
O75874 IDHC_HUMAN Liver cancer [ICD-11: 2C12]
O75874 IDHC_HUMAN Malignant haematopoietic neoplasm [ICD-11: 2B33]
O75874 IDHC_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
O75874 IDHC_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
O75874 IDHC_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P84022 SMAD3_HUMAN Herpes simplex infection [ICD-11: 1F00]
P84022 SMAD3_HUMAN Kidney fibrosis [ICD-11: GC01]