Basic Information

Terpenoid ID TKC105684
Chirality TKC105685
Cell line 0
Protein target 1
DiseaseNCIT 0
ORDO 0
ICD 15

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC105684 P35372 Mu-type opioid receptor OPRM1 >10000 nM Ki
TKC105684 P41143 Delta-type opioid receptor OPRD1 >10000 nM Ki
TKC105684 P41145 Kappa-type opioid receptor OPRK1 6 nM Ki
TKC105684 P41145 Kappa-type opioid receptor OPRK1 3 nM EC50
TKC105684 P32300 Delta-type opioid receptor Oprd1 >1000 nM Ki
TKC105684 P33535 Mu-type opioid receptor Oprm1 >1000 nM Ki

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P35372 OPRM_HUMAN Acute pain [ICD-11: MG31]
P35372 OPRM_HUMAN Bowel habit change [ICD-11: ME05]
P35372 OPRM_HUMAN Breathing abnormality [ICD-11: MD11]
P35372 OPRM_HUMAN Chronic pain [ICD-11: MG30]
P35372 OPRM_HUMAN Corneal disease [ICD-11: 9A76-9A78]
P35372 OPRM_HUMAN Cough [ICD-11: MD12]
P35372 OPRM_HUMAN Depression [ICD-11: 6A70-6A7Z]
P35372 OPRM_HUMAN Digestive system disease [ICD-11: DE2Z]
P35372 OPRM_HUMAN Irritable bowel syndrome [ICD-11: DD91]
P35372 OPRM_HUMAN Large intestine motility disorder [ICD-11: DB32]
P35372 OPRM_HUMAN Mental/behavioural/neurodevelopmental disorder [ICD-11: 6E20-6E8Z]
P35372 OPRM_HUMAN Migraine [ICD-11: 8A80]
P35372 OPRM_HUMAN Obesity [ICD-11: 5B80-5B81]
P35372 OPRM_HUMAN Opioid use disorder [ICD-11: 6C43]
P35372 OPRM_HUMAN Pain [ICD-11: MG30-MG3Z]
P35372 OPRM_HUMAN Pruritus [ICD-11: EC90]
P35372 OPRM_HUMAN Sensation disturbance [ICD-11: MB40]
P35372 OPRM_HUMAN Spinal pain [ICD-11: ME84]
P35372 OPRM_HUMAN General pain disorder [ICD-11: 8E43]
P35372 OPRM_HUMAN Neuropathy [ICD-11: 8C0Z]
P35372 OPRM_HUMAN Binge eating disorder [ICD-11: 6B82]
P35372 OPRM_HUMAN Substance abuse [ICD-11: 6C40]
P35372 OPRM_HUMAN Coronary vasospastic disease [ICD-11: BA85]
P35372 OPRM_HUMAN Headache [ICD-11: 8A80-8A84]
P35372 OPRM_HUMAN Abnormal micturition [ICD-11: MF50]
P35372 OPRM_HUMAN Unspecific substance use disorder [ICD-11: 6C4Z]
P35372 OPRM_HUMAN Asthma [ICD-11: CA23]
P35372 OPRM_HUMAN Lung cancer [ICD-11: 2C25]
P35372 OPRM_HUMAN Movement disorder [ICD-11: 8A07-8A0Z]
P35372 OPRM_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
P41143 OPRD_HUMAN Bowel habit change [ICD-11: ME05]
P41143 OPRD_HUMAN Chronic pain [ICD-11: MG30]
P41143 OPRD_HUMAN Cough [ICD-11: MD12]
P41143 OPRD_HUMAN Irritable bowel syndrome [ICD-11: DD91]
P41143 OPRD_HUMAN Pain [ICD-11: MG30-MG3Z]
P41143 OPRD_HUMAN Spinal pain [ICD-11: ME84]
P41143 OPRD_HUMAN Anxiety disorder [ICD-11: 6B00-6B0Z]
P41143 OPRD_HUMAN Rheumatoid arthritis [ICD-11: FA20]
P41143 OPRD_HUMAN Coronary vasospastic disease [ICD-11: BA85]
P41143 OPRD_HUMAN Functional bladder disorder [ICD-11: GC50]
P41143 OPRD_HUMAN Migraine [ICD-11: 8A80]
P41143 OPRD_HUMAN Opioid use disorder [ICD-11: 6C43]
P41143 OPRD_HUMAN Unspecific substance use disorder [ICD-11: 6C4Z]
P41143 OPRD_HUMAN Obesity [ICD-11: 5B80-5B81]
P41143 OPRD_HUMAN Substance abuse [ICD-11: 6C40]
P41143 OPRD_HUMAN Abnormal micturition [ICD-11: MF50]
P41143 OPRD_HUMAN Bladder disorder [ICD-11: GC01]
P41143 OPRD_HUMAN Depression [ICD-11: 6A70-6A7Z]
P41143 OPRD_HUMAN Ejaculatory dysfunction [ICD-11: HA03]
P41143 OPRD_HUMAN Ischemic heart disease [ICD-11: BA40-BA6Z]
P41145 OPRK_HUMAN Non-specific cutaneous vascular sympton [ICD-11: ME64]
P41145 OPRK_HUMAN Pain [ICD-11: MG30-MG3Z]
P41145 OPRK_HUMAN Prurigo [ICD-11: EC91]
P41145 OPRK_HUMAN Pruritus [ICD-11: EC90]
P41145 OPRK_HUMAN Irritable bowel syndrome [ICD-11: DD91]
P41145 OPRK_HUMAN Chronic pain [ICD-11: MG30]
P41145 OPRK_HUMAN Depression [ICD-11: 6A70-6A7Z]
P41145 OPRK_HUMAN Substance abuse [ICD-11: 6C40]
P41145 OPRK_HUMAN Bipolar disorder [ICD-11: 6A60]
P41145 OPRK_HUMAN Coronary vasospastic disease [ICD-11: BA85]
P41145 OPRK_HUMAN Opioid use disorder [ICD-11: 6C43]
P41145 OPRK_HUMAN Unspecific substance use disorder [ICD-11: 6C4Z]
P41145 OPRK_HUMAN Obesity [ICD-11: 5B80-5B81]
P41145 OPRK_HUMAN Indeterminate colitis [ICD-11: DD72]
P41145 OPRK_HUMAN Neurodegenerative disorder [ICD-11: 8A20-8A23]
P41145 OPRK_HUMAN Non-specific cutaneous vascular sympton [ICD-11: ME64]
P41145 OPRK_HUMAN Pain [ICD-11: MG30-MG3Z]
P41145 OPRK_HUMAN Prurigo [ICD-11: EC91]
P41145 OPRK_HUMAN Pruritus [ICD-11: EC90]
P41145 OPRK_HUMAN Irritable bowel syndrome [ICD-11: DD91]
P41145 OPRK_HUMAN Chronic pain [ICD-11: MG30]
P41145 OPRK_HUMAN Depression [ICD-11: 6A70-6A7Z]
P41145 OPRK_HUMAN Substance abuse [ICD-11: 6C40]
P41145 OPRK_HUMAN Bipolar disorder [ICD-11: 6A60]
P41145 OPRK_HUMAN Coronary vasospastic disease [ICD-11: BA85]
P41145 OPRK_HUMAN Opioid use disorder [ICD-11: 6C43]
P41145 OPRK_HUMAN Unspecific substance use disorder [ICD-11: 6C4Z]
P41145 OPRK_HUMAN Obesity [ICD-11: 5B80-5B81]
P41145 OPRK_HUMAN Indeterminate colitis [ICD-11: DD72]
P41145 OPRK_HUMAN Neurodegenerative disorder [ICD-11: 8A20-8A23]