Basic Information

Terpenoid ID TKC104558
Cell line 0
Protein target 13
DiseaseNCIT 0
ORDO 0
ICD 22

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC104558 HepG2 14125.0 nM Potency C3728 Orphanet_449

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC104558 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 TDP1 16360 nM Potency
TKC104558 O75874 Isocitrate dehydrogenase [NADP] cytoplasmic IDH1 29093 nM Potency
TKC104558 O95398 Rap guanine nucleotide exchange factor 3 RAPGEF3 22387 nM Potency
TKC104558 P43220 Glucagon-like peptide 1 receptor GLP1R 11220 nM Potency
TKC104558 P84022 Mothers against decapentaplegic homolog 3 SMAD3 11220 nM Potency
TKC104558 Q77YF9 Protein Vpr vpr 50119 nM Potency
TKC104558 Q99700 Ataxin-2 ATXN2 39811 nM Potency
TKC104558 O75164 Lysine-specific demethylase 4A KDM4A 44668 nM Potency
TKC104558 O75496 Geminin GMNN 29093 nM Potency
TKC104558 P37840 Alpha-synuclein SNCA 28184 nM Potency
TKC104558 P39748 Flap endonuclease 1 FEN1 35481 nM Potency
TKC104558 Q13148 TAR DNA-binding protein 43 TARDBP 35481 nM Potency
TKC104558 P83916 Chromobox protein homolog 1 CBX1 22387 nM Potency
TKC104558 P61088 Ubiquitin-conjugating enzyme E2 N UBE2N >20000 nM IC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
O75874 IDHC_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
O75874 IDHC_HUMAN Liver cancer [ICD-11: 2C12]
O75874 IDHC_HUMAN Malignant haematopoietic neoplasm [ICD-11: 2B33]
O75874 IDHC_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
O75874 IDHC_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
O75874 IDHC_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
O95398 RPGF3_HUMAN Epidermal dysplasias [ICD-11: EK90]
P43220 GLP1R_HUMAN Cardiovascular disease [ICD-11: BA00-BE2Z]
P43220 GLP1R_HUMAN Obesity [ICD-11: 5B80-5B81]
P43220 GLP1R_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
P43220 GLP1R_HUMAN Type-1/2 diabete [ICD-11: 5A10-5A11]
P43220 GLP1R_HUMAN Acute diabete complication [ICD-11: 5A2Y]
P43220 GLP1R_HUMAN Diabetes mellitus [ICD-11: 5A10]
P43220 GLP1R_HUMAN Dyspepsia [ICD-11: MD92]
P43220 GLP1R_HUMAN Irritable bowel syndrome [ICD-11: DD91]
P43220 GLP1R_HUMAN Intracranial injury [ICD-11: NA07]
P43220 GLP1R_HUMAN Non-alcoholic fatty liver disease [ICD-11: DB92]
P84022 SMAD3_HUMAN Herpes simplex infection [ICD-11: 1F00]
P84022 SMAD3_HUMAN Kidney fibrosis [ICD-11: GC01]
P37840 SYUA_HUMAN Parkinsonism [ICD-11: 8A00]
P37840 SYUA_HUMAN Alzheimer disease [ICD-11: 8A20]
P37840 SYUA_HUMAN Autonomic nervous system disorder [ICD-11: 8D87]
Q13148 TADBP_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
Q13148 TADBP_HUMAN Alzheimer disease [ICD-11: 8A20]