Basic Information

Terpenoid ID TKC104414
Cell line 0
Protein target 17
DiseaseNCIT 0
ORDO 0
ICD 26

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC104414 HepG2 17783.0 nM Potency C3728 Orphanet_449

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC104414 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 TDP1 18356 nM Potency
TKC104414 O75874 Isocitrate dehydrogenase [NADP] cytoplasmic IDH1 29093 nM Potency
TKC104414 O95398 Rap guanine nucleotide exchange factor 3 RAPGEF3 56234 nM Potency
TKC104414 P43220 Glucagon-like peptide 1 receptor GLP1R 14125 nM Potency
TKC104414 P84022 Mothers against decapentaplegic homolog 3 SMAD3 11220 nM Potency
TKC104414 Q77YF9 Protein Vpr vpr 28184 nM Potency
TKC104414 Q99700 Ataxin-2 ATXN2 35481 nM Potency
TKC104414 O75164 Lysine-specific demethylase 4A KDM4A 31623 nM Potency
TKC104414 O75496 Geminin GMNN 25929 nM Potency
TKC104414 P01215 Glycoprotein hormones alpha chain CGA 12589 nM Potency
TKC104414 P37840 Alpha-synuclein SNCA 31623 nM Potency
TKC104414 Q13148 TAR DNA-binding protein 43 TARDBP 35481 nM Potency
TKC104414 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1 50119 nM Potency
TKC104414 Q96QE3 ATPase family AAA domain-containing protein 5 ATAD5 29081 nM Potency
TKC104414 O75604 Ubiquitin carboxyl-terminal hydrolase 2 USP2 28184 nM Potency
TKC104414 O00167 Eyes absent homolog 2 EYA2 100000 nM Potency
TKC104414 Q99816 Tumor susceptibility gene 101 protein TSG101 31623 nM Potency

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
O75874 IDHC_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
O75874 IDHC_HUMAN Liver cancer [ICD-11: 2C12]
O75874 IDHC_HUMAN Malignant haematopoietic neoplasm [ICD-11: 2B33]
O75874 IDHC_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
O75874 IDHC_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
O75874 IDHC_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
O95398 RPGF3_HUMAN Epidermal dysplasias [ICD-11: EK90]
P43220 GLP1R_HUMAN Cardiovascular disease [ICD-11: BA00-BE2Z]
P43220 GLP1R_HUMAN Obesity [ICD-11: 5B80-5B81]
P43220 GLP1R_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
P43220 GLP1R_HUMAN Type-1/2 diabete [ICD-11: 5A10-5A11]
P43220 GLP1R_HUMAN Acute diabete complication [ICD-11: 5A2Y]
P43220 GLP1R_HUMAN Diabetes mellitus [ICD-11: 5A10]
P43220 GLP1R_HUMAN Dyspepsia [ICD-11: MD92]
P43220 GLP1R_HUMAN Irritable bowel syndrome [ICD-11: DD91]
P43220 GLP1R_HUMAN Intracranial injury [ICD-11: NA07]
P43220 GLP1R_HUMAN Non-alcoholic fatty liver disease [ICD-11: DB92]
P84022 SMAD3_HUMAN Herpes simplex infection [ICD-11: 1F00]
P84022 SMAD3_HUMAN Kidney fibrosis [ICD-11: GC01]
P37840 SYUA_HUMAN Parkinsonism [ICD-11: 8A00]
P37840 SYUA_HUMAN Alzheimer disease [ICD-11: 8A20]
P37840 SYUA_HUMAN Autonomic nervous system disorder [ICD-11: 8D87]
Q13148 TADBP_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
Q13148 TADBP_HUMAN Alzheimer disease [ICD-11: 8A20]
Q13526 PIN1_HUMAN Lung cancer [ICD-11: 2C25]
Q13526 PIN1_HUMAN Nasopharyngeal cancer [ICD-11: 2B6B]
O75604 UBP2_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
Q99816 TS101_HUMAN Influenza [ICD-11: 1E30-1E32]