Basic Information

Terpenoid ID TKC095638
Cell line 0
Protein target 4
DiseaseNCIT 0
ORDO 0
ICD 9

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC095638 4T1 4T1-A; 4T1.0; 4T1/WT 10000.0 nM IC50 C21678
TKC095638 HCT-116 HCT-116; HCT.116; HCT_116; HCT116; HCT116wt; CoCL2 52300.0 nM IC50 C4910
TKC095638 HepG2 55000.0 nM IC50 C3728 Orphanet_449
TKC095638 HeLa HELA; Hela; He La; He-La; HeLa-CCL2; Henrietta Lacks cells; Helacyton gartleri 20.0 % Activity C27677

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC095638 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 TDP1 29855 nM Potency
TKC095638 P18031 Tyrosine-protein phosphatase non-receptor type 1 PTPN1 45610 nM IC50
TKC095638 O94782 Ubiquitin carboxyl-terminal hydrolase 1 USP1 35481 nM Potency
TKC095638 P0DTD1 Replicase polyprotein 1ab rep 12 % Inhibition
TKC095638 P78417 Glutathione S-transferase omega-1 GSTO1 4000 nM IC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P18031 PTN1_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
P18031 PTN1_HUMAN Acute diabete complication [ICD-11: 5A2Y]
P18031 PTN1_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
P18031 PTN1_HUMAN Obesity [ICD-11: 5B80-5B81]
P18031 PTN1_HUMAN Ophthalmic devices/implants/grafts injury [ICD-11: PK97]
P18031 PTN1_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
P18031 PTN1_HUMAN Metabolic disorder [ICD-11: 5C50-5D2Z]
P18031 PTN1_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
O94782 UBP1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P78417 GSTO1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]