Basic Information

Terpenoid ID TKC078094
Chirality TKC103681
Cell line 0
Protein target 9
DiseaseNCIT 0
ORDO 0
ICD 22

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC078094 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 TDP1 146 nM Potency
TKC078094 O75874 Isocitrate dehydrogenase [NADP] cytoplasmic IDH1 206 nM Potency
TKC078094 P84022 Mothers against decapentaplegic homolog 3 SMAD3 5 nM Potency
TKC078094 Q16236 Nuclear factor erythroid 2-related factor 2 NFE2L2 73 nM Potency
TKC078094 Q77YF9 Protein Vpr vpr 28184 nM Potency
TKC078094 Q932Y6 Beta-lactamase bla(tem-2) 49729 nM IC50
TKC078094 Q99700 Ataxin-2 ATXN2 21 nM Potency
TKC078094 O43353 Receptor-interacting serine/threonine-protein kinase 2 RIPK2 >49729 nM IC50
TKC078094 O75496 Geminin GMNN 73 nM Potency
TKC078094 Q13148 TAR DNA-binding protein 43 TARDBP 12589 nM Potency

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
O75874 IDHC_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
O75874 IDHC_HUMAN Liver cancer [ICD-11: 2C12]
O75874 IDHC_HUMAN Malignant haematopoietic neoplasm [ICD-11: 2B33]
O75874 IDHC_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
O75874 IDHC_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
O75874 IDHC_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P84022 SMAD3_HUMAN Herpes simplex infection [ICD-11: 1F00]
P84022 SMAD3_HUMAN Kidney fibrosis [ICD-11: GC01]
Q16236 NF2L2_HUMAN Ataxic disorder [ICD-11: 8A03]
Q16236 NF2L2_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
Q16236 NF2L2_HUMAN Glaucoma [ICD-11: 9C61]
Q16236 NF2L2_HUMAN Lung cancer [ICD-11: 2C25]
Q16236 NF2L2_HUMAN Macular degeneration [ICD-11: 9B75]
Q16236 NF2L2_HUMAN Melanoma [ICD-11: 2C30]
Q16236 NF2L2_HUMAN Mental/behavioural/neurodevelopmental disorder [ICD-11: 6E20-6E8Z]
Q16236 NF2L2_HUMAN Pulmonary hypertension [ICD-11: BB01]
Q16236 NF2L2_HUMAN Subarachnoid haemorrhage [ICD-11: 8B01]
Q16236 NF2L2_HUMAN Urinary system clinical sympton [ICD-11: MF8Y]
Q16236 NF2L2_HUMAN Non-alcoholic fatty liver disease [ICD-11: DB92]
Q16236 NF2L2_HUMAN Alpha-1-antitrypsin deficiency [ICD-11: 5C5A]
Q16236 NF2L2_HUMAN Motor neuron disease [ICD-11: 8B60]
Q16236 NF2L2_HUMAN Multiple sclerosis [ICD-11: 8A40]
O43353 RIPK2_HUMAN Cardiovascular disease [ICD-11: BA00-BE2Z]
O43353 RIPK2_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
Q13148 TADBP_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
Q13148 TADBP_HUMAN Alzheimer disease [ICD-11: 8A20]