Basic Information

Terpenoid ID TKC077819
Cell line 0
Protein target 2
DiseaseNCIT 0
ORDO 0
ICD 6

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC077819 HL-60 HL 60; HL.60 HL60; Human Leukemia-60 14.0 % Activity C9154 Orphanet_519
TKC077819 HCT-116 HCT-116; HCT.116; HCT_116; HCT116; HCT116wt; CoCL2 1800.0 nM IC50 C4910
TKC077819 HSC-2 HSC2 6400.0 nM IC50 C4833 Orphanet_502363
TKC077819 MCF7 5200.0 nM IC50 C4194
TKC077819 BT-549 BT 549; BT.549; BT549 6607.0 nM GI50 C4194
TKC077819 SK-MEL-2 SK-Mel-2; SK-Mel 2; SK-mel-2; SK-MEL2; SK.MEL.2; SK Mel 2; SK MEL 2; SKMEL-2; SKMEL2; SKmel2; SK-ML2; SKml2 9333.0 nM GI50 C3224
TKC077819 MDA-MB-231 MDA_MB_231; MDA-MB 231; MDA.MB.231; MDA MB 231; MDA MB231; MDA Mb231; MDA-MB231; MDAMB-231; MDAMB231; MDA-231; MDA-231P; MDA231; MDA231-BRE; MB231; MD Anderson-Metastatic Breast-231 4560.0 nM GI50 C5214
TKC077819 DU-145 DU-145; Du-145; DU 145; DU_145; DU.145; Duke University 145 7700.0 nM GI50 C4863
TKC077819 PC-3 PC3; PC.3 3600.0 nM GI50 C4863
TKC077819 UO-31 UO.31; UO31; U031 3690.0 nM GI50 C9385 Orphanet_217071
TKC077819 TK-10 TK.10; TK 10; TK10 10700.0 nM GI50 C4033 Orphanet_319276
TKC077819 SN12C SN-12C 2880.0 nM GI50 C9385 Orphanet_217071
TKC077819 RXF 393 RXF393L; RXF-393 L; RXF-393; RXF 393; RXF.393; RXF393; RXF 393NL 2570.0 nM GI50 C9385 Orphanet_217071
TKC077819 ACHN 2930.0 nM GI50 C6975 Orphanet_319298
TKC077819 A498 A498 2818.0 nM GI50 C9385 Orphanet_217071
TKC077819 786-0 786-o; 786O; 786-0; 786.O; 786-O RCC; RCC 786-O; RCC_7860; RCC 7860; 7860; 786-0WT 3060.0 nM GI50 C9385 Orphanet_217071
TKC077819 SK-OV-3 SKOV-3; SK-OV3; SK.OV.3; SKOV3; Skov3; SKO3 12800.0 nM GI50 C7978
TKC077819 OVCAR-5 OVCAR 5; NIH:OVCAR-5; OVCAR.5; OVCAR5; Ovcar5; OVCA5 15849.0 nM GI50 C105555
TKC077819 OVCAR-3 Ovcar-3; OVCAR 3; OVCAR.3; NIH:OVCAR-3; NIH:Ovcar-3; NIH:OVCAR3; NIH-OVCAR-3; NIHOVCAR3; OVCAR3; Ovcar3 7040.0 nM GI50 C105555
TKC077819 UACC-62 UACC 62; UACC.62; UACC62; University of Arizona Cell Culture-62 1950.0 nM GI50 C3224
TKC077819 SK-MEL-5 SK-Mel-5; SK MEL 5; SK.MEL.5; SK-MEL5; SKMel-5; SKMEL-5; SKMEL5; SKMel5; SKmel5; AA-Mel 2860.0 nM GI50 C3510
TKC077819 SK-MEL-28 SK-Mel-28; SK.MEL.28; SK-MEL 28; SK MEL-28; SK MEL 28; SK Mel 28; SKMel-28; SKMEL-28; SK-MEL28; SK-Mel28; SK Mel28; SKMEL28; SKMel28; SKmel28; SKML-28; SK28; AU-Mel; P-36; P36 4890.0 nM GI50 C3510
TKC077819 M14 M14-MEL; UCLA-SO-M14; UCLA SO M14; UCLA-SO-14; UCLASO-M14; Melanoma 14; M-14 7710.0 nM GI50 C3802
TKC077819 U-251 U-251 MG; U-251-MG; U-251_MG; U251-MG; U251MG; U-251; U251; U251n; U251N; 251 MG; 251MG; 251 MG(6) 2620.0 nM GI50 C60781 Orphanet_94
TKC077819 SNB-19 SNB.19; SNB19; Surgical Neurology Branch-19 4898.0 nM GI50 C60781 Orphanet_94
TKC077819 SF-295 SF-295; SF.295; SF 295 1445.0 nM GI50 C3058 Orphanet_360
TKC077819 SF-268 SF-268; SF.268; SF 268 5870.0 nM GI50 C60781 Orphanet_94
TKC077819 COLO 205 Colo 205; CoLo 205; COLO-205; Colo-205; COLO.205; Colo205; COLO205; Co 205; Colorado 205 3631.0 nM GI50 C4349
TKC077819 NCI-H522 NCI.H522; H522; H-522; NCI-522; NCI522; NCIH522 4169.0 nM GI50 C3512
TKC077819 NCI-H322M NCI.H322M; H322M; H-322M; H-322m 3620.0 nM GI50 C2923
TKC077819 NCI-H23 NCI.H23; NCI H23; H-23; H23; NCIH23 7240.0 nM GI50 C3512
TKC077819 NCI-H226 NCI.H226; NCI H226; H226; H-226; HUT-226; HUT 226; NCIH226 5090.0 nM GI50 C45662 Orphanet_50251
TKC077819 HOP-92 HOP 92; HOP.92; HOP92; Hop92; Hopkins-92 1510.0 nM GI50 C2926
TKC077819 HOP-62 HOP 62; Hop 62; HOP.62; HOP62; Hop62; Hopkins-62 7413.0 nM GI50 C3512
TKC077819 A549 430.0 nM IC50 C3512
TKC077819 MDA-MB-468 MDA-MB 468; MDA-MB468; MDAMB468; MDA-468; MDA468; MB468; MD Anderson-Metastatic Breast-468 4169.0 nM GI50 C5214

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC077819 Q00653 Nuclear factor NF-kappa-B p100 subunit NFKB2 1020 nM IC50
TKC077819 O14920 Inhibitor of nuclear factor kappa-B kinase subunit beta IKBKB 4240 nM IC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
Q00653 NFKB2_HUMAN Ulcerative colitis [ICD-11: DD71]
O14920 IKKB_HUMAN Mature B-cell lymphoma [ICD-11: 2A85]
O14920 IKKB_HUMAN Alzheimer disease [ICD-11: 8A20]
O14920 IKKB_HUMAN Osteoarthritis [ICD-11: FA00-FA05]
O14920 IKKB_HUMAN Acne vulgaris [ICD-11: ED80]
O14920 IKKB_HUMAN Rheumatoid arthritis [ICD-11: FA20]